World's Best Scientists 2026 revealed!
Pascale Cossart

Pascale Cossart

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Best Female Scientists
2025
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Microbiology
France
2026

D-Index & Metrics

Best Female Scientists

D-Index
147
Citations
74713
World Ranking
171
National Ranking
7

Microbiology

D-Index
150
Citations
76928
World Ranking
33
National Ranking
3

Research.com Recognitions

  • 2026 - Research.com Microbiology in France Leader Award
  • 2025 - Research.com Best Female Scientists Award
  • 2025 - Research.com Microbiology in France Leader Award
  • 2023 - Research.com Microbiology in France Leader Award
  • 2022 - Research.com Microbiology in France Leader Award
  • 2014 - Member of the National Academy of Medicine (NAM)
  • 2013 - International Balzan Prize
  • 2010 - Fellow of the Royal Society, United Kingdom
  • 2009 - Member of the National Academy of Sciences
  • 2007 - Robert Koch Prize
  • 2001 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Microbiology and Immunology
  • 1998 - Member of Academia Europaea
  • 1998 - Richard Lounsbery Award, National Academy of Sciences and the French Academy of Sciences for her fundamental discoveries in microbiology dealing with mechanisms of bacterial entry and intracellular host motility.
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Pascale Cossart is affiliated with the Institut Pasteur in France and has contributed extensively to the field of biochemistry, genetics, and molecular biology, with 44 publications in this main area. Their research spans multiple subfields including molecular biology, biotechnology, genetics, food science, and endocrinology, reflecting a multidisciplinary approach to microbiology and cellular processes.

The scientist's work frequently addresses key topics such as Listeria monocytogenes in Food Safety, mitochondrial function and pathology, essential oils and antimicrobial activity, as well as bacterial research focused on Vibrio and Escherichia coli. Other areas explored include evolution and genetic dynamics, and antibiotic resistance in bacteria.

Key publications by Pascale Cossart include:

  • "Impact of the gut microbiota on the m6A epitranscriptome of mouse cecum and liver," 2020, Nature Communications
  • "Insect decline: immediate action is needed," 2021, Comptes Rendus Biologies
  • "Listeria monocytogenes Exploits Mitochondrial Contact Site and Cristae Organizing System Complex Subunit Mic10 To Promote Mitochondrial Fragmentation and Cellular Infection," 2020, mBio
  • "Listeriolysin S: A bacteriocin from Listeria monocytogenes that induces membrane permeabilization in a contact-dependent manner," 2021, Proceedings of the National Academy of Sciences
  • "Mitochondrial respiration restricts Listeria monocytogenes infection by slowing down host cell receptor recycling," 2021, Cell Reports

Their research has been published in various prominent scientific venues, with frequent appearances in:

  • Trends in Cell Biology
  • Comptes Rendus Biologies
  • bioRxiv (Cold Spring Harbor Laboratory)
  • microLife
  • Nature Communications

Collaboration is a notable aspect of their career, with frequent co-authors including:

  • Ilaria Carnevale
  • J. Bakker
  • Patrick Scheffmann
  • Nihal Alton-Bonnet
  • Wolfgang Baumeister

The scientist has received multiple awards and recognized memberships in scientific organizations. These include membership in the National Academy of Medicine (2014), the International Balzan Prize (2013), fellowship of the Royal Society in the United Kingdom (2010), membership in the National Academy of Sciences (2009), and the Robert Koch Prize (2007).

Additional honors include membership in the German National Academy of Sciences Leopoldina since 2001 for contributions in microbiology and immunology, membership in Academia Europaea since 1998, the Richard Lounsbery Award from the National Academy of Sciences and the French Academy of Sciences in 1998 for fundamental discoveries in microbiology related to bacterial entry mechanisms and intracellular motility, and membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Comparative Genomics of Listeria Species

    P Glaser;L Frangeul;C Buchrieser;C Rusniok

  • Bacterial invasion: the paradigms of enteroinvasive pathogens.

    Pascale Cossart;Philippe J. Sansonetti

  • Bacterial Adhesion and Entry into Host Cells

    Javier Pizarro-Cerdá;Javier Pizarro-Cerdá;Javier Pizarro-Cerdá;Pascale Cossart;Pascale Cossart;Pascale Cossart

  • L. monocytogenes-induced actin assembly requires the actA gene product, a surface protein.

    C. Kocks;E. Gouin;M. Tabouret;P. Berche

  • E-Cadherin Is the Receptor for Internalin, a Surface Protein Required for Entry of L. monocytogenes into Epithelial Cells

    Jérôme Mengaud;Hélène Ohayon;Pierre Gounon;René-Marc Mège

  • Entry of L. monocytogenes into cells is mediated by internalin, a repeat protein reminiscent of surface antigens from gram-positive cocci

    J.-L. Gaillard;P. Berche;C. Frehel;E. Gouln

  • The Listeria transcriptional landscape from saprophytism to virulence

    Alejandro Toledo-Arana;Olivier Dussurget;Olivier Dussurget;Olivier Dussurget;Georgios Nikitas;Georgios Nikitas;Nina Sesto;Nina Sesto;Nina Sesto

  • Exploitation of Mammalian Host Cell Functions by Bacterial Pathogens

    B. Brett Finlay;Pascale Cossart;Pascale Cossart

  • Septins: the fourth component of the cytoskeleton

    Serge Mostowy;Pascale Cossart;Pascale Cossart;Pascale Cossart

  • How bacterial pathogens colonize their hosts and invade deeper tissues.

    David Ribet;Pascale Cossart

  • Listeria monocytogenes: towards a complete picture of its physiology and pathogenesis.

    Lilliana Radoshevich;Pascale Cossart;Pascale Cossart;Pascale Cossart

  • An RNA thermosensor controls expression of virulence genes in Listeria monocytogenes.

    Jörgen Johansson;Pierre Mandin;Adriana Renzoni;Claude Chiaruttini

  • Listeria monocytogenes: a multifaceted model

    Mélanie Hamon;Hélène Bierne;Hélène Bierne;Hélène Bierne;Pascale Cossart;Pascale Cossart;Pascale Cossart

  • A transgenic model for listeriosis: role of internalin in crossing the intestinal barrier.

    Marc Lecuit;Sandrine Vandormael-Pournin;Jean Lefort;Michel Huerre

  • Molecular determinants of Listeria monocytogenes pathogenesis

    D A Portnoy;T Chakraborty;W Goebel;P Cossart

  • A single amino acid in E-cadherin responsible for host specificity towards the human pathogen Listeria monocytogenes.

    Marc Lecuit;Shaynoor Dramsi;Cara Gottardi;Mary Fedor-Chaiken

  • Entry of Listeria monocytogenes into hepatocytes requires expression of InIB, a surface protein of the internalin multigene family

    Shaynoor Dramsi;Indranil Biswas;Emmanuelle Maguin;Laurence Braun

  • Prokaryotic transcriptomics: a new view on regulation, physiology and pathogenicity

    Rotem Sorek;Pascale Cossart

  • Actin-based motility of vaccinia virus.

    Sally Cudmore;Pascale Cossart;Gareth Griffiths;Michael Way

Frequent Co-Authors

Javier Pizarro-Cerdá
Javier Pizarro-Cerdá Institut Pasteur
Marie-Anne Nahori
Marie-Anne Nahori Institut Pasteur
Marc Lecuit
Marc Lecuit Institut Pasteur
Hélène Bierne
Hélène Bierne INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
Olivier Dussurget
Olivier Dussurget Université Paris Cité
Serge Mostowy
Serge Mostowy London School of Hygiene & Tropical Medicine
Shaynoor Dramsi
Shaynoor Dramsi Institut Pasteur
Carmen Buchrieser
Carmen Buchrieser Institut Pasteur
Philippe Glaser
Philippe Glaser Institut Pasteur
Francisco García-del Portillo
Francisco García-del Portillo Spanish National Research Council

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