World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
102
Citations
38972
World Ranking
372
National Ranking
170

Research.com Recognitions

  • 2017 - Fellow, National Academy of Inventors
  • 2013 - Member of the National Academy of Sciences

Overview

Daniel A. Portnoy is affiliated with the University of California, Berkeley in the United States. Their research primarily focuses on the intersection of biochemistry, genetics, molecular biology, immunology, and microbiology, with a notable emphasis on Listeria monocytogenes and its role in food safety and immune responses.

The scientist has published extensively in prominent scientific venues. Frequent publication platforms include bioRxiv (Cold Spring Harbor Laboratory) with 12 publications, mBio with 4 publications, Infection and Immunity with 4 publications, PLoS Pathogens with 3 publications, and Proceedings of the National Academy of Sciences with 3 publications.

Among their recent published papers are the following:

  • Role of the transcriptional regulator SP140 in resistance to bacterial infections via repression of type I interferons, 2021, eLife
  • Detoxification of methylglyoxal by the glyoxalase system is required for glutathione availability and virulence activation in Listeria monocytogenes, 2021, PLoS Pathogens
  • (p)ppGpp and c-di-AMP Homeostasis Is Controlled by CbpB in Listeria monocytogenes, 2020, mBio
  • Why is Listeria monocytogenes such a potent inducer of CD8+ T-cells?, 2020, Cellular Microbiology
  • TLR2 and endosomal TLR-mediated secretion of IL-10 and immune suppression in response to phagosome-confined Listeria monocytogenes, 2020, PLoS Pathogens

The scientist's work covers specific topics related to:

  • Listeria monocytogenes in Food Safety
  • Interferon and immune responses
  • Immune Response and Inflammation
  • Salmonella and Campylobacter epidemiology
  • Microbial Inactivation Methods
  • Immunotherapy and Immune Responses
  • Cytokine Signaling Pathways and Interactions

Their main fields of study encompass:

  • Biochemistry, Genetics and Molecular Biology
  • Immunology and Microbiology

Subfields addressed in their research include:

  • Biotechnology
  • Immunology
  • Food Science
  • Molecular Biology
  • Oncology

Daniel A. Portnoy frequently collaborates with a range of co-authors, including Rafael Rivera-Lugo, Michel DuPage, Andrea Anaya-Sanchez, Jesse Garcia Castillo, and Ying Feng. These collaborators have contributed to multiple joint publications enhancing the breadth of the research output.

Recognition for their contributions includes membership in the National Academy of Sciences awarded in 2013 and being named a Fellow of the National Academy of Inventors in 2017.

Best Publications

  • Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite, Listeria monocytogenes.

    L G Tilney;D A Portnoy

  • Role of hemolysin for the intracellular growth of Listeria monocytogenes.

    D A Portnoy;P S Jacks;D J Hinrichs

  • c-di-AMP Secreted by Intracellular Listeria monocytogenes Activates a Host Type I Interferon Response

    Joshua J. Woodward;Anthony T. Iavarone;Daniel A. Portnoy

  • Characterization of plasmids and plasmid-associated determinants of Yersinia enterocolitica pathogenesis.

    D A Portnoy;S L Moseley;S Falkow

  • The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9.

    Koichi Tabeta;Kasper Hoebe;Edith M. Janssen;Xin Du

  • The N-Ethyl-N-Nitrosourea-Induced Goldenticket Mouse Mutant Reveals an Essential Function of Sting in the In Vivo Interferon Response to Listeria monocytogenes and Cyclic Dinucleotides

    John Demian Sauer;Katia Sotelo-Troha;Jakob Von Moltke;Kathryn M. Monroe

  • STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade

    Juan Fu;David B. Kanne;Meredith Leong;Laura Hix Glickman

  • Molecular determinants of Listeria monocytogenes pathogenesis

    D A Portnoy;T Chakraborty;W Goebel;P Cossart

  • The rate of actin-based motility of intracellular Listeria monocytogenes equals the rate of actin polymerization.

    Julie A. Theriot;Timothy J. Mitchison;Lewis G. Tilney;Daniel A. Portnoy

  • Dual roles of plcA in Listeria monocytogenes pathogenesis

    Andrew Camilli;Lewis G. Tilney;Daniel A. Portnoy

  • Interaction of human Arp2/3 complex and the Listeria monocytogenes ActA protein in actin filament nucleation.

    Matthew D. Welch;Jody Rosenblatt;Justin Skoble;Daniel A. Portnoy

  • The cell biology of Listeria monocytogenes infection the intersection of bacterial pathogenesis and cell-mediated immunity

    Daniel A. Portnoy;Victoria Auerbuch;Ian J. Glomski

  • Patterns of pathogenesis: discrimination of pathogenic and nonpathogenic microbes by the innate immune system.

    Russell E. Vance;Ralph R. Isberg;Daniel A. Portnoy

  • A flavin-based extracellular electron transfer mechanism in diverse Gram-positive bacteria.

    Samuel H. Light;Lin Su;Rafael Rivera-Lugo;Jose A. Cornejo

  • The two distinct phospholipases C of Listeria monocytogenes have overlapping roles in escape from a vacuole and cell-to-cell spread.

    G A Smith;H Marquis;S Jones;N C Johnston

  • Construction, Characterization, and Use of Two Listeria monocytogenes Site-Specific Phage Integration Vectors

    Peter Lauer;Man Yin Nora Chow;Martin J. Loessner;Daniel A. Portnoy

  • Mice Lacking the Type I Interferon Receptor Are Resistant to Listeria monocytogenes

    Victoria Auerbuch;Dirk G Brockstedt;Nicole P Meyer-Morse;Mary Xd O'Riordan

  • Mycobacterium Tuberculosis Activates the DNA-Dependent Cytosolic Surveillance Pathway within Macrophages

    Paolo S. Manzanillo;Michael U. Shiloh;Daniel A. Portnoy;Jeffery S. Cox

  • Bacillus subtilis expressing a haemolysin gene from Listeria monocytogenes can grow in mammalian cells

    Jacek Bielecki;Philip Youngman;Patricia Connelly;Daniel A. Portnoy

  • Structural heterogeneity and functional domains of murine immunoglobulin G Fc receptors

    Jeffrey V. Ravetch;Andrew D. Luster;Richard Weinshank;Jarema Kochan

Frequent Co-Authors

Thomas W. Dubensky
Thomas W. Dubensky Tempest Therapeutics
Julie A. Theriot
Julie A. Theriot University of Washington
Richard Calendar
Richard Calendar University of California, Berkeley
Stanley Falkow
Stanley Falkow Stanford University
Lewis G. Tilney
Lewis G. Tilney University of Pennsylvania
Russell E. Vance
Russell E. Vance University of California, Berkeley
Jeffery S. Cox
Jeffery S. Cox University of California, Berkeley
Pascale Cossart
Pascale Cossart Institut Pasteur
Matthew D. Welch
Matthew D. Welch University of California, Berkeley
Yvonne Paterson
Yvonne Paterson University of Pennsylvania

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