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Genetics

D-Index
55
Citations
15243
World Ranking
3555
National Ranking
1542

Overview

Kyle J. Gaulton is affiliated with the University of California, San Diego in the United States and has an extensive publication record focused on biochemistry, genetics, molecular biology, and medicine. Their research predominantly covers molecular biology, genetics, and related subfields such as surgery, endocrinology, diabetes and metabolism, and cancer research.

Their work addresses key topics including pancreatic function and diabetes, diabetes and associated disorders, single-cell and spatial transcriptomics, diabetes management and research, genetic associations and epidemiology, epigenetics and DNA methylation, and RNA research and splicing.

Frequent co-authors in their research include:

  • Joshua Chiou
  • Sebastian Preißl
  • Maike Sander
  • Bing Ren
  • Mei-Lin Okino

Gaulton has published in a variety of venues, with the most common being:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Nature
  • Zenodo (CERN European Organization for Nuclear Research)
  • Diabetes

Selected recent papers by Gaulton include:

  • A single-cell atlas of chromatin accessibility in the human genome, 2021, Cell
  • Interpreting type 1 diabetes risk with genetics and single-cell epigenomics, 2021, Nature
  • An atlas of dynamic chromatin landscapes in mouse fetal development, 2020, Nature
  • Characterizing cis-regulatory elements using single-cell epigenomics, 2022, Nature Reviews Genetics
  • Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes, 2020, eLife

Their research contributions frequently involve multiomic profiling and single-cell epigenomics to understand cellular mechanisms in health and disease, particularly related to diabetes and genetic regulation.

Best Publications

  • The genetic architecture of type 2 diabetes

    Christian Fuchsberger;Christian Fuchsberger;Jason A. Flannick;Jason A. Flannick;Tanya M. Teslovich;Anubha Mahajan

  • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

    Anubha Mahajan;Min Jin Go;Weihua Zhang;Jennifer E. Below

  • An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

    Robert A. Scott;Laura J. Scott;Reedik Mägi;Letizia Marullo

  • A map of open chromatin in human pancreatic islets

    Kyle J. Gaulton;Takao Nammo;Lorenzo Pasquali;Jeremy M. Simon

  • Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

    Nicole M Warrington;Robin N Beaumont;Momoko Horikoshi;Felix R Day

  • Genome-wide associations for birth weight and correlations with adult disease

    Momoko Horikoshi;Robin N. Beaumont;Felix R. Day;Nicole M. Warrington;Nicole M. Warrington

  • Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants

    Lorenzo Pasquali;Kyle J Gaulton;Kyle J Gaulton;Kyle J Gaulton;Santiago A Rodríguez-Seguí;Loris Mularoni

  • Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance

    Luca A Lotta;Pawan Gulati;Felix R Day;Felicity Payne

  • Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis.

    Miriam S Udler;Jaegil Kim;Marcin von Grotthuss;Sílvia Bonàs-Guarch

  • Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

    Kyle J Gaulton;Kyle J Gaulton;Teresa Ferreira;Yeji Lee;Anne Raimondo

  • Detection of human adaptation during the past 2000 years

    Yair Field;Yair Field;Evan A Boyle;Natalie Telis;Ziyue Gao;Ziyue Gao

  • A single-cell atlas of chromatin accessibility in the human genome

    Kai Zhang;Kai Zhang;James D. Hocker;James D. Hocker;Michael Miller;Xiaomeng Hou

  • An atlas of dynamic chromatin landscapes in mouse fetal development

    David U. Gorkin;David U. Gorkin;Iros Barozzi;Iros Barozzi;Yuan Zhao;Yuan Zhao;Yanxiao Zhang

  • Interpreting type 1 diabetes risk with genetics and single-cell epigenomics

    Joshua Chiou;Joshua Chiou;Ryan J. Geusz;Mei-Lin Okino;Jee Yun Han

  • Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol

    Leslie A Lange;Youna Hu;He Zhang;Chenyi Xue

  • The miRNA Profile of Human Pancreatic Islets and Beta-Cells and Relationship to Type 2 Diabetes Pathogenesis

    Martijn van de Bunt;Martijn van de Bunt;Kyle J. Gaulton;Leopold Parts;Ignasi Moran

  • Choice of transcripts and software has a large effect on variant annotation

    Davis J. McCarthy;Davis J. McCarthy;Peter Humburg;Alexander Kanapin;Manuel A. Rivas

  • Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

    Mahajan A;Spracklen Cn;Zhang W;Ng Mc

  • The genetic architecture of type 2 diabetes

    Christian Fuchsberger;Jason Flannick;Tanya M. Teslovich;Anubha Mahajan

  • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

    Anubha Mahajan;Min Jin Go;Weihua Zhang;Jennifer E. Below

Frequent Co-Authors

Andrew P. Morris
Andrew P. Morris University of Liverpool
Cecilia M. Lindgren
Cecilia M. Lindgren University of Oxford
Inga Prokopenko
Inga Prokopenko University of Surrey
Anna L. Gloyn
Anna L. Gloyn Stanford University
David Altshuler
David Altshuler Harvard University
Erik Ingelsson
Erik Ingelsson Stanford University
Jose C. Florez
Jose C. Florez Harvard University
Torben Hansen
Torben Hansen University of Copenhagen

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