His primary scientific interests are in Innate immune system, Cell biology, Microbiology, NLRC4 and Lymphokine-activated killer cell. His Innate immune system research is multidisciplinary, incorporating elements of Computational biology and Caspase-11. His Cell biology study combines topics in areas such as Quorum sensing, Virulence, Genetics and Cholera toxin.
His work in Microbiology addresses subjects such as Legionella pneumophila, which are connected to disciplines such as Intracellular and Autophagy. The concepts of his Lymphokine-activated killer cell study are interwoven with issues in Natural killer T cell and Receptor. His work is dedicated to discovering how Interleukin 21, Natural killer cell are connected with MHC class I and other disciplines.
Russell E. Vance focuses on Cell biology, Innate immune system, Inflammasome, Microbiology and Immune system. His studies in Cell biology integrate themes in fields like Natural killer T cell, Interleukin 21, Lymphokine-activated killer cell, Cytosol and Receptor. His work carried out in the field of Receptor brings together such families of science as Molecular biology and Natural killer cell.
He works mostly in the field of Innate immune system, limiting it down to topics relating to Interferon and, in certain cases, Stimulator of interferon genes and Host cell cytosol, as a part of the same area of interest. The various areas that Russell E. Vance examines in his Inflammasome study include Cytokine and Programmed cell death. His Microbiology research integrates issues from Legionella pneumophila, Macrophage and Gene, Virulence.
His primary areas of investigation include Inflammasome, Innate immune system, Microbiology, Immune system and Cell biology. Specifically, his work in Inflammasome is concerned with the study of NLRC4. His Innate immune system study incorporates themes from Pyroptosis, Interferon and Computational biology.
His Microbiology study combines topics in areas such as Legionella pneumophila, Gene and Immunity. His Stimulator of interferon genes and Type I interferon production study in the realm of Immune system connects with subjects such as Ring. His research in Cell biology intersects with topics in Membrane cholesterol, Cholesterol and Quarantine.
The scientist’s investigation covers issues in Inflammasome, Receptor, Microbiology, Innate immune system and Interferon. His studies deal with areas such as Effector, Cell biology and Computational biology as well as Inflammasome. His Microbiology research is multidisciplinary, incorporating elements of Legionella pneumophila and Gene, Intracellular parasite.
His work on Innate immunology as part of his general Innate immune system study is frequently connected to Mechanism, thereby bridging the divide between different branches of science. He has researched Interferon in several fields, including IRF5, Interferon regulatory factors and Immunity. His NLRC4 study which covers NAIP that intersects with Phosphorylation, Serine and Signal transduction.
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STING is a direct innate immune sensor of cyclic di-GMP
Dara L. Burdette;Kathryn M. Monroe;Katia Sotelo-Troha;Jeff S. Iwig.
Quorum-sensing regulators control virulence gene expression in Vibrio cholerae
Jun Zhu;Melissa B. Miller;Russell E. Vance;Michelle Dziejman.
Proceedings of the National Academy of Sciences of the United States of America (2002)
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
Eric M. Kofoed;Russell E. Vance.
Self-tolerance of natural killer cells
David H. Raulet;Russell E. Vance.
Nature Reviews Immunology (2006)
Mouse CD94/NKG2A Is a Natural Killer Cell Receptor for the Nonclassical Major Histocompatibility Complex (MHC) Class I Molecule Qa-1b
Russell E. Vance;Jennifer R. Kraft;John D. Altman;Peter E. Jensen.
Journal of Experimental Medicine (1998)
A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules
Nadine C. Fernandez;Emmanuel Treiner;Emmanuel Treiner;Russell E. Vance;Russell E. Vance;Amanda M. Jamieson;Amanda M. Jamieson.
Intracellular innate immune surveillance devices in plants and animals
Jonathan D. G. Jones;Russell E. Vance;Jeffery L. Dangl.
The N-Ethyl-N-Nitrosourea-Induced Goldenticket Mouse Mutant Reveals an Essential Function of Sting in the In Vivo Interferon Response to Listeria monocytogenes and Cyclic Dinucleotides
John Demian Sauer;Katia Sotelo-Troha;Jakob Von Moltke;Kathryn M. Monroe.
Infection and Immunity (2011)
Regulation of the natural killer cell receptor repertoire.
David H. Raulet;Russell E. Vance;Christopher W. McMahon.
Annual Review of Immunology (2001)
The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING
Elie J. Diner;Dara L. Burdette;Stephen C. Wilson;Kathryn M. Monroe.
Cell Reports (2013)
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