2026 Petr Broz: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	56	14150	13013	260	230	127	21713

Overview

Petr Broz is affiliated with the University of Lausanne in Switzerland. Their research spans a range of fields primarily within Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology. The principal subfields of study include Molecular Biology, Immunology, Epidemiology, Physiology, and Public Health, Environmental and Occupational Health.

The scientist's work covers several main topics:

Inflammasome and immune disorders
Interferon and immune responses
Heme Oxygenase-1 and Carbon Monoxide
Immune Response and Inflammation
Cell death mechanisms and regulation
Erythrocyte Function and Pathophysiology
IL-33, ST2, and ILC Pathways

Petr Broz has published numerous papers, with recent notable publications including:

Apoptotic cell death in disease-Current understanding of the NCCD 2023 (2023), published in Cell Death and Differentiation
Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria (2020), published in Nature Communications
Caspase-8-dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality (2020), published in Science Advances
Structural basis of NINJ1-mediated plasma membrane rupture in cell death (2023), published in Nature
RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling (2021), published in Proceedings of the National Academy of Sciences

Frequent co-authors of Petr Broz include:

Benjamin Demarco
Kateryna Shkarina
José Carlos Santos
Kaiwen Chen
Saray Ramos

Their research outputs are often published in venues such as:

bioRxiv (Cold Spring Harbor Laboratory)
Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
Nature
The EMBO Journal
Methods in molecular biology

Best Publications

Inflammasomes: mechanism of assembly, regulation and signalling

Petr Broz;Vishva M. Dixit

2936
Citations
The gasdermins, a protein family executing cell death and inflammation

Petr Broz;Pablo Pelegrín;Feng Shao

1148
Citations
GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

Lorenzo Sborgi;Sebastian Rühl;Estefania Mulvihill;Joka Pipercevic

1026
Citations
Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing.

Petr Broz;Jakob von Moltke;Jonathan W. Jones;Russell E. Vance

711
Citations
Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella

Petr Broz;Kim Newton;Mohamed Lamkanfi;Sanjeev Mariathasan

669
Citations
Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1

Petr Broz;Thomas Ruby;Kamila Belhocine;Donna M. Bouley

606
Citations
Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps

Kaiwen W. Chen;Kaiwen W. Chen;Mercedes Monteleone;Dave Boucher;Gabriel Sollberger

598
Citations
Newly described pattern recognition receptors team up against intracellular pathogens

Petr Broz;Denise M. Monack

593
Citations
Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis

Jonathan W. Jones;Nobuhiko Kayagaki;Petr Broz;Thomas Henry

581
Citations
ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation

Sebastian Rühl;Sebastian Rühl;Kateryna Shkarina;Benjamin Demarco;Rosalie Heilig

558
Citations
Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases

Etienne Meunier;Mathias S. Dick;Roland F. Dreier;Nura Schürmann

522
Citations
Caspase-11 activates a canonical NLRP3 inflammasome by promoting K(+) efflux.

Sebastian Rühl;Petr Broz

481
Citations
K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria

Christina J. Groß;Ritu Mishra;Katharina S. Schneider;Guillaume Médard

446
Citations
The V-antigen of Yersinia forms a distinct structure at the tip of injectisome needles.

Catherine A. Mueller;Petr Broz;Shirley A. Müller;Philippe Ringler

439
Citations
The Needle Length of Bacterial Injectisomes Is Determined by a Molecular Ruler

Laure Journet;Céline Agrain;Petr Broz;Guy R. Cornelis

386
Citations
ASC filament formation serves as a signal amplification mechanism for inflammasomes

Mathias S. Dick;Lorenzo Sborgi;Sebastian Rühl;Sebastian Hiller

370
Citations
The Gasdermin-D pore acts as a conduit for IL-1β secretion in mice

Rosalie Heilig;Rosalie Heilig;Mathias S. Dick;Lorenzo Sborgi;Etienne Meunier

344
Citations
Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida.

Etienne Meunier;Pierre Wallet;Roland F Dreier;Stéphanie Costanzo

338
Citations
Extrinsic and intrinsic apoptosis activate pannexin-1 to drive NLRP3 inflammasome assembly.

Kaiwen W Chen;Benjamin Demarco;Rosalie Heilig;Kateryna Shkarina

319
Citations
Molecular mechanisms of inflammasome activation during microbial infections.

Petr Broz;Denise M. Monack

302
Citations