World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
15737
World Ranking
16949
National Ranking
476

Overview

Si Ming Man is affiliated with the Australian National University in Australia and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their scholarly work spans multiple subfields including molecular biology, immunology, epidemiology, public health, environmental and occupational health, and infectious diseases.

Their research topics are primarily focused on inflammasome and immune disorders, interferon and immune responses, heme oxygenase-1 and carbon monoxide, immune response and inflammation, streptococcal infections and treatments, Kawasaki disease and coronary complications, as well as autoimmune and inflammatory disorders research.

Si Ming Man has published notable papers, such as:

  • "Bacillus cereus: Epidemiology, Virulence Factors, and Host-Pathogen Interactions" (2020) in Trends in Microbiology
  • "Cell biology of inflammasome activation" (2021) in Trends in Cell Biology
  • "Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway" (2022) in Immunity
  • "Context-dependent functions of pattern recognition receptors in cancer" (2022) in Nature Reviews Cancer
  • "Molecular mechanisms activating the NAIP-NLRC4 inflammasome: Implications in infectious disease, autoinflammation, and cancer" (2020) in Immunological Reviews

Frequent coauthors in Si Ming Man's research include Abhimanu Pandey, Chinh Ngo, Daniel Enosi Tuipulotu, Shouya Feng, and Nadeem O. Kaakoush.

Their work is often published in venues such as Zenodo (CERN European Organization for Nuclear Research), Nature Communications, Nature Immunology, bioRxiv (Cold Spring Harbor Laboratory), and The Journal of Immunology, reflecting a diverse engagement with both preprint and peer-reviewed platforms.

Best Publications

  • Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases.

    Si Ming Man;Rajendra Karki;Thirumala-Devi Kanneganti

  • Global Epidemiology of Campylobacter Infection

    Nadeem O. Kaakoush;Natalia Castaño-Rodríguez;Hazel M. Mitchell;Si Ming Man;Si Ming Man

  • Regulation of inflammasome activation

    Si Ming Man;Thirumala-Devi Kanneganti

  • ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways

    Teneema Kuriakose;Si Ming Man;R. K. Subbarao Malireddi;Rajendra Karki

  • Converging roles of caspases in inflammasome activation, cell death and innate immunity.

    Si Ming Man;Thirumala-Devi Kanneganti

  • The clinical importance of emerging Campylobacter species

    Si Ming Man

  • Emerging Activators and Regulators of Inflammasomes and Pyroptosis.

    Yansong Xue;Daniel Enosi Tuipulotu;Wei Hong Tan;Callum Kay

  • The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection

    Si Ming Man;Si Ming Man;Rajendra Karki;R K Subbarao Malireddi;Geoffrey Neale

  • Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex

    Si Ming Man;Lee J. Hopkins;Eileen Nugent;Susan Cox

  • Inflammasomes and Cancer

    Rajendra Karki;Si Ming Man;Thirumala-Devi Kanneganti

  • AIM2 inflammasome in infection, cancer, and autoimmunity: Role in DNA sensing, inflammation, and innate immunity.

    Si Ming Man;Rajendra Karki;Thirumala-Devi Kanneganti

  • Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer.

    Si Ming Man;Qifan Zhu;Qifan Zhu;Liqin Zhu;Zhiping Liu

  • Mechanisms of Gasdermin Family Members in Inflammasome Signaling and Cell Death.

    Shouya Feng;Daniel Fox;Si Ming Man

  • IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes

    Si Ming Man;Rajendra Karki;Miwa Sasai;David E. Place

  • Inflammasomes in the gastrointestinal tract: infection, cancer and gut microbiota homeostasis.

    Si Ming Man

  • Concerted Activation of the AIM2 and NLRP3 Inflammasomes Orchestrates Host Protection against Aspergillus Infection

    Rajendra Karki;Si Ming Man;R.K. Subbarao Malireddi;Prajwal Gurung

  • Salmonella Infection Induces Recruitment of Caspase-8 to the Inflammasome To Modulate IL-1β Production

    Si Ming Man;Panagiotis Tourlomousis;Lee Hopkins;Tom P. Monie

  • The role of bacteria and pattern-recognition receptors in Crohn's disease.

    Si Ming Man;Nadeem O. Kaakoush;Hazel M. Mitchell

  • IL-1 Family Members Mediate Cell Death, Inflammation and Angiogenesis in Retinal Degenerative Diseases

    Yvette Wooff;Si Ming Man;Riemke Aggio-Bruce;Riccardo Natoli

  • NLRC3 is an inhibitory sensor of PI3K–mTOR pathways in cancer

    Rajendra Karki;Si Ming Man;R. K. Subbarao Malireddi;Sannula Kesavardhana

Frequent Co-Authors

Thirumala-Devi Kanneganti
Thirumala-Devi Kanneganti St. Jude Children's Research Hospital
Hazel M. Mitchell
Hazel M. Mitchell University of New South Wales
Peter Vogel
Peter Vogel St. Jude Children's Research Hospital
Mohamed Lamkanfi
Mohamed Lamkanfi Ghent University
Geoffrey Neale
Geoffrey Neale St. Jude Children's Research Hospital
Clare E. Bryant
Clare E. Bryant University of Cambridge
Benjamin T. Kile
Benjamin T. Kile University of Adelaide
Marc R. Wilkins
Marc R. Wilkins University of New South Wales
David C. S. Huang
David C. S. Huang Walter and Eliza Hall Institute of Medical Research
Stephen H. Leppla
Stephen H. Leppla National Institutes of Health

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students interested in Biology and Biochemistry, a variety of online degree options can expand career opportunities in the healthcare and science fields. These programs often include flexible learning formats, making it easier for working professionals or those balancing other commitments to continue their education.

Many graduates consider advancing into specialized fields such as pharmacy or nursing. For example, pursuing an online pharmacy program can lead to leadership roles in pharmaceutical research or clinical practice. Likewise, a doctor of nursing practice degree is ideal for those looking to drive innovation in patient care and healthcare systems without extensive on-site clinical requirements.

Those with an interest in healthcare management may find a pathway through the best online dha programs, designed to develop executive skills for administrative and policy roles. Alternatively, students passionate about the science of human movement and wellness can pursue an online bachelor's degree in exercise science, opening doors to research, sports medicine, or health promotion.

Exploring these online degrees can help you tailor your educational journey and career to fit your unique interests and goals in the vast world of biology, biochemistry, and health sciences.

Best Scientists Citing Si Ming Man

Trending Scientists

Recently Published Articles