Masahiro Yamamoto

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in Japan Leader Award
• 2025 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Best Publications

• Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

  Hiroki Kato;Osamu Takeuchi;Shintaro Sato;Mitsutoshi Yoneyama

  4575
  Citations

• Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway.

  Masahiro Yamamoto;Shintaro Sato;Hiroaki Hemmi;Katsuaki Hoshino

  4156
  Citations

• Cell type-specific involvement of RIG-I in antiviral response

  Hiroki Kato;Shintaro Sato;Mitsutoshi Yoneyama;Masahiro Yamamoto

  2007
  Citations

• Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling.

  Masahiro Yamamoto;Shintaro Sato;Kiyotoshi Mori;Katsuaki Hoshino

  1675
  Citations

• TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

  Masahiro Yamamoto;Shintaro Sato;Hiroaki Hemmi;Satoshi Uematsu

  1454
  Citations

• Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4

  Masahiro Yamamoto;Shintaro Sato;Hiroaki Hemmi;Hideki Sanjo

  1386
  Citations

• Interferon-|[alpha]| induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

  Taro Kawai;Shintaro Sato;Ken J. Ishii;Cevayir Coban

  1306
  Citations

• Essential function for the kinase TAK1 in innate and adaptive immune responses.

  Shintaro Sato;Hideki Sanjo;Kiyoshi Takeda;Jun Ninomiya-Tsuji

  1140
  Citations

• Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation.

  Fuminori Tokunaga;Shin-ichi Sakata;Shin-ichi Sakata;Yasushi Saeki;Yoshinori Satomi

  1087
  Citations

• ATP drives lamina propria T H 17 cell differentiation

  Koji Atarashi;Junichi Nishimura;Tatsuichiro Shima;Yoshinori Umesaki

  1048
  Citations

• Toll/IL-1 Receptor Domain-Containing Adaptor Inducing IFN-β (TRIF) Associates with TNF Receptor-Associated Factor 6 and TANK-Binding Kinase 1, and Activates Two Distinct Transcription Factors, NF-κB and IFN-Regulatory Factor-3, in the Toll-Like Receptor Signaling

  Shintaro Sato;Masanaka Sugiyama;Masahiro Yamamoto;Yasuyuki Watanabe

  1006
  Citations

• A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA

  Ken J Ishii;Cevayir Coban;Hiroki Kato;Ken Takahashi

  964
  Citations

• The RNA Helicase Lgp2 Inhibits TLR-Independent Sensing of Viral Replication by Retinoic Acid-Inducible Gene-I

  Simon Rothenfusser;Nadege Goutagny;Gary DiPerna;Mei Gong

  880
  Citations

• The roles of two IκB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection

  Hiroaki Hemmi;Osamu Takeuchi;Shintaro Sato;Masahiro Yamamoto

  866
  Citations

• Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin

  Cevayir Coban;Ken J. Ishii;Taro Kawai;Hiroaki Hemmi

  857
  Citations

• Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IκBζ

  Masahiro Yamamoto;Soh Yamazaki;Satoshi Uematsu;Shintaro Sato

  641
  Citations

• Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-α induction

  Satoshi Uematsu;Shintaro Sato;Masahiro Yamamoto;Tomonori Hirotani

  633
  Citations

• Essential role of IPS-1 in innate immune responses against RNA viruses

  Himanshu Kumar;Taro Kawai;Hiroki Kato;Shintaro Sato

  622
  Citations

• Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells.

  Satoshi Uematsu;Myoung Ho Jang;Nicolas Chevrier;Zijin Guo

  542
  Citations

• TIR domain-containing adaptors define the specificity of TLR signaling.

  Masahiro Yamamoto;Kiyoshi Takeda;Shizuo Akira

  498
  Citations