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Tatsuya Saitoh

Tatsuya Saitoh

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
39843
World Ranking
14126
National Ranking
1000

Overview

Tatsuya Saitoh is affiliated with Osaka University in Japan and has contributed to multiple research areas encompassing biochemistry, genetics, molecular biology, immunology, microbiology, and medicine. Their work prominently addresses subfields such as molecular biology, immunology, physiology, pulmonary and respiratory medicine, and infectious diseases.

The scientist's main topics of investigation include inflammasome and immune disorders, phagocytosis and immune regulation, galectins and cancer biology, heme oxygenase-1 and carbon monoxide, macrophage migration inhibitory factor, interstitial lung diseases and idiopathic pulmonary fibrosis, as well as RNA interference and gene delivery.

Recent publications by Tatsuya Saitoh include the following:

  • Tim4 recognizes carbon nanotubes and mediates phagocytosis leading to granuloma formation (2021) published in Cell Reports
  • Macrophage Response Driven by Extracellular ATP (2021) published in Biological and Pharmaceutical Bulletin
  • Zinc and iron dynamics in human islet amyloid polypeptide-induced diabetes mouse model (2023) published in Scientific Reports
  • Lipid Nanoparticle with 1,2-Di-O-octadecenyl-3-trimethylammonium-propane as a Component Lipid Confers Potent Responses of Th1 Cells and Antibody against Vaccine Antigen (2024) published in ACS Nano
  • Nanaomycin E inhibits NLRP3 inflammasome activation by preventing mitochondrial dysfunction (2022) published in International Immunology

Frequent publication venues for their research include:

  • International Immunology
  • Proceedings for Annual Meeting of The Japanese Pharmacological Society
  • Cell Reports
  • ACS Nano
  • Scientific Reports

Their frequent coauthors include Naoki Takemura, Yixi Pan, Kenta Ikoma, Manabu Taura, and Akiyoshi Nakayama, indicating collaborations spanning various projects in related research fields.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production.

    Tatsuya Saitoh;Naonobu Fujita;Myoung Ho Jang;Satoshi Uematsu

  • Autophagy in infection, inflammation and immunity

    Vojo Deretic;Tatsuya Saitoh;Shizuo Akira

  • Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

    Kohichi Matsunaga;Tatsuya Saitoh;Keisuke Tabata;Hiroko Omori

  • The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

    Takashi Satoh;Osamu Takeuchi;Alexis Vandenbon;Koubun Yasuda

  • Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome

    Takuma Misawa;Michihiro Takahama;Tatsuya Kozaki;Hanna Lee

  • Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response

    Tatsuya Saitoh;Naonobu Fujita;Takuya Hayashi;Keigo Takahara

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Neutrophil extracellular traps mediate a host defense response to human immunodeficiency virus-1.

    Tatsuya Saitoh;Jun Komano;Yasunori Saitoh;Takuma Misawa

  • Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IκBζ

    Masahiro Yamamoto;Soh Yamazaki;Satoshi Uematsu;Shintaro Sato

  • Autophagy and autophagy-related proteins in the immune system

    Shusaku T Shibutani;Tatsuya Saitoh;Heike Nowag;Christian Münz

  • Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2.

    Tatsukata Kawagoe;Shintaro Sato;Kazufumi Matsushita;Hiroki Kato

  • Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

    Ikuko Maejima;Atsushi Takahashi;Hiroko Omori;Tomonori Kimura

  • The Ubiquitin Ligase TRIM56 Regulates Innate Immune Responses to Intracellular Double-Stranded DNA

    Tetsuo Tsuchida;Jian Zou;Tatsuya Saitoh;Himanshu Kumar;Himanshu Kumar

  • Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L

    Kohichi Matsunaga;Eiji Morita;Tatsuya Saitoh;Shizuo Akira

  • Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1

    Tatsuya Saitoh;Adrian Tun-Kyi;Akihide Ryo;Masahiro Yamamoto

  • DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking

    Takeshi Kondo;Junya Kobayashi;Tatsuya Saitoh;Kenta Maruyama

  • TWEAK Induces NF-κB2 p100 Processing and Long Lasting NF-κB Activation

    Tatsuya Saitoh;Masafumi Nakayama;Hiroyasu Nakano;Hideo Yagita

  • Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling.

    Masahiro Yamamoto;Toru Okamoto;Kiyoshi Takeda;Shintaro Sato

Frequent Co-Authors

Shizuo Akira
Shizuo Akira Osaka University
Tamotsu Yoshimori
Tamotsu Yoshimori Osaka University
Naoki Yamamoto
Naoki Yamamoto Kyoto University
Osamu Takeuchi
Osamu Takeuchi Kyoto University
Taro Kawai
Taro Kawai Nara Institute of Science and Technology
Shoji Yamaoka
Shoji Yamaoka Tokyo Medical and Dental University
Takeshi Noda
Takeshi Noda Osaka University
Masahiro Yamamoto
Masahiro Yamamoto Osaka University
Yoshiharu Matsuura
Yoshiharu Matsuura Osaka University
Noboru Mizushima
Noboru Mizushima University of Tokyo

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