What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Virology, Interferon, Virus, Hepatitis C virus and RIG-I.
His studies deal with areas such as RNA and Immunology, Innate immune system, Immune system as well as Virology.
His Interferon research is multidisciplinary, relying on both Transcription factor, Interferon regulatory factors, Protein kinase R, Signal transduction and Regulation of gene expression.
His study focuses on the intersection of Virus and fields such as TLR3 with connections in the field of Herpes simplex virus, TRIF and Vesicular stomatitis virus.
His RIG-I research includes elements of Pathogen and MDA5.
His research integrates issues of RNA virus and Cell biology in his study of RIG-I-like receptor.
His most cited work include:
- Shared and Unique Functions of the DExD/H-Box Helicases RIG-I, MDA5, and LGP2 in Antiviral Innate Immunity (1301 citations)
- Immune Signaling by RIG-I-like Receptors (1115 citations)
- Viruses and interferon: a fight for supremacy (1022 citations)
What are the main themes of his work throughout his whole career to date?
Michael Gale spends much of his time researching Virology, Innate immune system, Virus, Immunology and Interferon.
His Virology course of study focuses on RIG-I and MDA5.
His Innate immune system research is multidisciplinary, incorporating perspectives in Acquired immune system, RNA virus and Signal transduction, Cell biology.
His Cell biology study combines topics in areas such as RNA and Inflammasome.
His Virus research integrates issues from Regulation of gene expression and Transcription factor.
In his research, EIF-2 kinase is intimately related to Protein kinase R, which falls under the overarching field of Interferon.
He most often published in these fields:
- Virology (62.06%)
- Innate immune system (35.77%)
- Virus (35.50%)
What were the highlights of his more recent work (between 2018-2021)?
- Virology (62.06%)
- Innate immune system (35.77%)
- Virus (35.50%)
In recent papers he was focusing on the following fields of study:
His main research concerns Virology, Innate immune system, Virus, Cell biology and Immunology.
His work carried out in the field of Virology brings together such families of science as Antibody and Immune system, Immunity.
Michael Gale has researched Innate immune system in several fields, including Interferon and Viral replication.
His study in Virus is interdisciplinary in nature, drawing from both ALVAC Vaccine and Coronavirus disease 2019.
His Cell biology research is multidisciplinary, incorporating elements of Cell, RNA, DNA, Messenger RNA and Programmed cell death.
His biological study spans a wide range of topics, including Microbiome and Disease.
Between 2018 and 2021, his most popular works were:
- Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19. (128 citations)
- The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons. (71 citations)
- Differential Activation of the Transcription Factor IRF1 Underlies the Distinct Immune Responses Elicited by Type I and Type III Interferons (50 citations)
In his most recent research, the most cited papers focused on:
Michael Gale focuses on Innate immune system, Cell biology, Virology, Antibody and Virus.
Michael Gale interconnects Interferon, MDA5, Viral replication and Immunity in the investigation of issues within Innate immune system.
His studies examine the connections between Interferon and genetics, as well as such issues in Inflammation, with regards to Disease.
His Cell biology research includes themes of RNA, Cell, IRF1 and Programmed cell death.
His studies in Virology integrate themes in fields like T cell, Replicon and Immunogenicity.
The concepts of his Virus study are interwoven with issues in DNA, DNA damage, Protein kinase A, Phosphorylation and Adenoviridae.
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