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Microbiology

D-Index
86
Citations
34121
World Ranking
822
National Ranking
381

Overview

Denise M. Monack is affiliated with Stanford University in the United States and has extensive research contributions primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans several subfields including Endocrinology, Food Science, Immunology, Infectious Diseases, and Molecular Biology.

Their research interests focus on microbial pathogenesis and host-pathogen interactions, particularly involving bacteria such as Salmonella, Campylobacter, Vibrio, and Escherichia coli. Central topics addressed in their publications include:

  • Salmonella and Campylobacter epidemiology
  • Vibrio bacteria research studies
  • Viral gastroenteritis research and epidemiology
  • Gut microbiota and health
  • Bacteriophages and microbial interactions
  • Escherichia coli research studies
  • Bacterial Genetics and Biotechnology

Denise M. Monack has published in a range of scientific venues, with multiple papers appearing in bioRxiv (Cold Spring Harbor Laboratory). Additional frequent publication venues include:

  • Current Opinion in Microbiology
  • mBio
  • PLoS Pathogens
  • Nature Protocols

Representative recent papers highlight their contributions to understanding host-pathogen dynamics and gastrointestinal biology:

  • "Controlling the polarity of human gastrointestinal organoids to investigate epithelial biology and infectious diseases" (2021, Nature Protocols)
  • "Retinoic Acid and Lymphotoxin Signaling Promote Differentiation of Human Intestinal M Cells" (2020, Gastroenterology)
  • "Upregulation of CD47 Is a Host Checkpoint Response to Pathogen Recognition" (2020, mBio)
  • "Spraying Small Water Droplets Acts as a Bacteriocide" (2020, QRB Discovery)
  • "One species, different diseases: the unique molecular mechanisms that underlie the pathogenesis of typhoidal Salmonella infections" (2023, Current Opinion in Microbiology)

Throughout their career, Denise M. Monack has collaborated with several researchers frequently, including Liliana M. Massis, Ramya Narasimhan, Trung H.M. Pham, Daniel Butler, and Sarah Ruddle. These collaborations have supported diverse investigations into microbial infections and immune responses.

Best Publications

  • Cryopyrin activates the inflammasome in response to toxins and ATP

    Sanjeev Mariathasan;David S. Weiss;Kim Newton;Jacqueline McBride

  • Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf.

    Sanjeev Mariathasan;Kim Newton;Denise M. Monack;Domagoj Vucic

  • Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens

    Katharine M. Ng;Jessica A. Ferreyra;Steven K. Higginbottom;Jonathan B. Lynch

  • Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation.

    Sanjeev Mariathasan;Denise M. Monack

  • The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1

    David Hersh;Denise M. Monack;Mark R. Smith;Nafisa Ghori

  • Salmonella typhimurium invasion induces apoptosis in infected macrophages

    Denise M. Monack;Barbel Raupach;Alexander E. Hromockyj;Stanley Falkow

  • Macrophage‐dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival

    Daniela Maria Cirillo;Raphael H. Valdivia;Denise M. Monack;Stanley Falkow

  • Persistent bacterial infections: the interface of the pathogen and the host immune system

    Denise M. Monack;Anne Mueller;Stanley Falkow

  • Two physically, functionally, and developmentally distinct peritoneal macrophage subsets

    Eliver Eid Bou Ghosn;Alexandra A. Cassado;Gregory R. Govoni;Takeshi Fukuhara

  • The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus.

    J. Antonio Gomez;Orly L. Wapinski;Yul W. Yang;Jean-François Bureau

  • Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing.

    Petr Broz;Jakob von Moltke;Jonathan W. Jones;Russell E. Vance

  • Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella

    Petr Broz;Kim Newton;Mohamed Lamkanfi;Sanjeev Mariathasan

  • Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1

    Petr Broz;Thomas Ruby;Kamila Belhocine;Donna M. Bouley

  • Yersinia signals macrophages to undergo apoptosis and YopJ is necessary for this cell death

    Denise M. Monack;Joan Mecsas;Nafisa Ghori;Stanley Falkow

  • Newly described pattern recognition receptors team up against intracellular pathogens

    Petr Broz;Denise M. Monack

  • Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis

    Jonathan W. Jones;Nobuhiko Kayagaki;Petr Broz;Thomas Henry

  • Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin

    Karla L. Lightfield;Jenny Persson;Sky W. Brubaker;Chelsea E. Witte

  • Salmonella typhimurium Persists within Macrophages in the Mesenteric Lymph Nodes of Chronically Infected Nramp1+/+ Mice and Can Be Reactivated by IFNγ Neutralization

    Denise M. Monack;Donna M. Bouley;Stanley Falkow

  • Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis

    Sanjeev Mariathasan;David S. Weiss;Vishva M. Dixit;Denise M. Monack

  • A Gut Commensal-Produced Metabolite Mediates Colonization Resistance to Salmonella Infection.

    Amanda Jacobson;Lilian Lam;Manohary Rajendram;Fiona Tamburini

  • Genome-wide screen for Salmonella genes required for long-term systemic infection of the mouse.

    Trevor D Lawley;Kaman Chan;Lucinda J Thompson;Charles C Kim

Frequent Co-Authors

Stanley Falkow
Stanley Falkow Stanford University
Petr Broz
Petr Broz University of Lausanne
Thomas Henry
Thomas Henry Claude Bernard University Lyon 1
Andreas J. Bäumler
Andreas J. Bäumler University of California, Davis
Julie A. Theriot
Julie A. Theriot University of Washington
Kim Newton
Kim Newton Genentech
Renée M. Tsolis
Renée M. Tsolis University of California, Davis
David A. Relman
David A. Relman Stanford University

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