What is she best known for?
The fields of study she is best known for:
- Gene
- Bacteria
- Immune system
Denise M. Monack mainly focuses on Microbiology, Inflammasome, Caspase 1, Innate immune system and Cell biology.
Her study in Microbiology is interdisciplinary in nature, drawing from both Francisella tularensis, Virulence and Salmonella.
Her NLRC4 and AIM2 study are her primary interests in Inflammasome.
Denise M. Monack combines subjects such as NALP3 and Inflammasome complex with her study of AIM2.
Her Innate immune system research integrates issues from Proinflammatory cytokine and Intracellular parasite.
Her studies in Cell biology integrate themes in fields like Immune system, Immunology, Mutant and Programmed cell death.
Her most cited work include:
- Cryopyrin activates the inflammasome in response to toxins and ATP (2276 citations)
- Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. (1408 citations)
- Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation. (732 citations)
What are the main themes of her work throughout her whole career to date?
Denise M. Monack mainly investigates Microbiology, Innate immune system, Salmonella, Inflammasome and Cell biology.
Her Microbiology research is multidisciplinary, incorporating perspectives in Francisella tularensis, Virulence, Bacteria and Salmonella enterica.
Her research in Innate immune system intersects with topics in Proinflammatory cytokine and Intracellular parasite.
Her research integrates issues of Salmonella typhi, Type three secretion system and Mesenteric lymph nodes in her study of Salmonella.
In her study, which falls under the umbrella issue of Inflammasome, Molecular biology is strongly linked to Secretion.
Her work deals with themes such as Cytokine and Caspase-11, which intersect with Cell biology.
She most often published in these fields:
- Microbiology (56.00%)
- Innate immune system (27.33%)
- Salmonella (22.67%)
What were the highlights of her more recent work (between 2017-2021)?
- Cell biology (21.33%)
- Microbiology (56.00%)
- Innate immune system (27.33%)
In recent papers she was focusing on the following fields of study:
The scientist’s investigation covers issues in Cell biology, Microbiology, Innate immune system, Immune system and Salmonella.
Her studies in Cell biology integrate themes in fields like Pyroptosis, Caspase and Programmed cell death.
Denise M. Monack combines Microbiology and Lipoprotein in her studies.
Her studies deal with areas such as Structural motif, Signal transduction and Gene expression as well as Innate immune system.
Her work on Microfold cell, Peyer's patch and Major histocompatibility complex as part of her general Immune system study is frequently connected to Central element and Transcytosis, thereby bridging the divide between different branches of science.
Her Salmonella study integrates concerns from other disciplines, such as Pathogen, Gene, Virulence and Typhoid fever.
Between 2017 and 2021, her most popular works were:
- A Gut Commensal-Produced Metabolite Mediates Colonization Resistance to Salmonella Infection. (114 citations)
- Controlling Epithelial Polarity: A Human Enteroid Model for Host-Pathogen Interactions. (86 citations)
- The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages. (60 citations)
In her most recent research, the most cited papers focused on:
- Gene
- Bacteria
- Immune system
Denise M. Monack focuses on Cell biology, Effector, Salmonella, Salmonella enterica and Pathogen.
The concepts of her Cell biology study are interwoven with issues in Pyroptosis and Cytoskeleton.
Her work carried out in the field of Effector brings together such families of science as Serine, Tyrosine kinase, M2 Macrophage, Macrophage polarization and Kinase.
Her Salmonella research integrates issues from Plasmid maintenance, Synteny and Gene, Virulence.
Denise M. Monack interconnects Antibiotics, Microbiology, Bacteroides, Propionate and Salmonella infection in the investigation of issues within Salmonella enterica.
Her biological study spans a wide range of topics, including Epithelium, Epithelial polarity, Spheroid, Polarity and Colonisation resistance.
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