Denise M. Monack mainly focuses on Microbiology, Inflammasome, Caspase 1, Innate immune system and Cell biology. Her study in Microbiology is interdisciplinary in nature, drawing from both Francisella tularensis, Virulence and Salmonella. Her NLRC4 and AIM2 study are her primary interests in Inflammasome.
Denise M. Monack combines subjects such as NALP3 and Inflammasome complex with her study of AIM2. Her Innate immune system research integrates issues from Proinflammatory cytokine and Intracellular parasite. Her studies in Cell biology integrate themes in fields like Immune system, Immunology, Mutant and Programmed cell death.
Denise M. Monack mainly investigates Microbiology, Innate immune system, Salmonella, Inflammasome and Cell biology. Her Microbiology research is multidisciplinary, incorporating perspectives in Francisella tularensis, Virulence, Bacteria and Salmonella enterica. Her research in Innate immune system intersects with topics in Proinflammatory cytokine and Intracellular parasite.
Her research integrates issues of Salmonella typhi, Type three secretion system and Mesenteric lymph nodes in her study of Salmonella. In her study, which falls under the umbrella issue of Inflammasome, Molecular biology is strongly linked to Secretion. Her work deals with themes such as Cytokine and Caspase-11, which intersect with Cell biology.
The scientist’s investigation covers issues in Cell biology, Microbiology, Innate immune system, Immune system and Salmonella. Her studies in Cell biology integrate themes in fields like Pyroptosis, Caspase and Programmed cell death. Denise M. Monack combines Microbiology and Lipoprotein in her studies.
Her studies deal with areas such as Structural motif, Signal transduction and Gene expression as well as Innate immune system. Her work on Microfold cell, Peyer's patch and Major histocompatibility complex as part of her general Immune system study is frequently connected to Central element and Transcytosis, thereby bridging the divide between different branches of science. Her Salmonella study integrates concerns from other disciplines, such as Pathogen, Gene, Virulence and Typhoid fever.
Denise M. Monack focuses on Cell biology, Effector, Salmonella, Salmonella enterica and Pathogen. The concepts of her Cell biology study are interwoven with issues in Pyroptosis and Cytoskeleton. Her work carried out in the field of Effector brings together such families of science as Serine, Tyrosine kinase, M2 Macrophage, Macrophage polarization and Kinase.
Her Salmonella research integrates issues from Plasmid maintenance, Synteny and Gene, Virulence. Denise M. Monack interconnects Antibiotics, Microbiology, Bacteroides, Propionate and Salmonella infection in the investigation of issues within Salmonella enterica. Her biological study spans a wide range of topics, including Epithelium, Epithelial polarity, Spheroid, Polarity and Colonisation resistance.
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Cryopyrin activates the inflammasome in response to toxins and ATP
Sanjeev Mariathasan;David S. Weiss;Kim Newton;Jacqueline McBride.
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf.
Sanjeev Mariathasan;Kim Newton;Denise M. Monack;Domagoj Vucic.
Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation.
Sanjeev Mariathasan;Denise M. Monack.
Nature Reviews Immunology (2007)
The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1
David Hersh;Denise M. Monack;Mark R. Smith;Nafisa Ghori.
Proceedings of the National Academy of Sciences of the United States of America (1999)
Salmonella typhimurium invasion induces apoptosis in infected macrophages
Denise M. Monack;Barbel Raupach;Alexander E. Hromockyj;Stanley Falkow.
Proceedings of the National Academy of Sciences of the United States of America (1996)
Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens
Katharine M. Ng;Jessica A. Ferreyra;Steven K. Higginbottom;Jonathan B. Lynch.
Macrophage‐dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival
Daniela Maria Cirillo;Raphael H. Valdivia;Denise M. Monack;Stanley Falkow.
Molecular Microbiology (1998)
Persistent bacterial infections: the interface of the pathogen and the host immune system
Denise M. Monack;Anne Mueller;Stanley Falkow.
Nature Reviews Microbiology (2004)
The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus.
J. Antonio Gomez;Orly L. Wapinski;Yul W. Yang;Jean-François Bureau.
Yersinia signals macrophages to undergo apoptosis and YopJ is necessary for this cell death
Denise M. Monack;Joan Mecsas;Nafisa Ghori;Stanley Falkow.
Proceedings of the National Academy of Sciences of the United States of America (1997)
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