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Makoto Tachibana

Makoto Tachibana

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
15243
World Ranking
17436
National Ranking
1259

Overview

Makoto Tachibana is affiliated with Osaka University in Japan. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with a notable focus on Medicine as well. They have contributed to various subfields including Molecular Biology, Genetics, Radiology, Nuclear Medicine and Imaging, Public Health, Environmental and Occupational Health, and Reproductive Medicine.

Tachibana's main research topics include:

  • Epigenetics and DNA Methylation
  • Cancer-related gene regulation
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Reproductive Biology and Fertility
  • Genomics and Chromatin Dynamics
  • Sexual Differentiation and Disorders
  • RNA modifications and cancer

The scientist has published in several venues with multiple publications in Science and Bone, as well as contributions to bioRxiv (Cold Spring Harbor Laboratory). Other venues include EMBO Reports and Nature.

Recent papers authored or co-authored by Tachibana include:

  • Generation of ovarian follicles from mouse pluripotent stem cells, 2021, Science
  • HP1 maintains protein stability of H3K9 methyltransferases and demethylases, 2022, EMBO Reports
  • The mouse Sry locus harbors a cryptic exon that is essential for male sex determination, 2020, Science
  • Meiosis-specific ZFP541 repressor complex promotes developmental progression of meiotic prophase towards completion during mouse spermatogenesis, 2021, Nature Communications
  • H3K9 Demethylases JMJD1A and JMJD1B Control Prospermatogonia to Spermatogonia Transition in Mouse Germline, 2020, Stem Cell Reports

Frequent co-authors in their research include:

  • Ryo Maeda
  • Yoichi Shinkai
  • Naoki Okashita
  • Hisashi Ideno
  • Kazuhisa Nakashima

Best Publications

  • G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis

    Makoto Tachibana;Kenji Sugimoto;Masami Nozaki;Jun Ueda

  • Partitioning and Plasticity of Repressive Histone Methylation States in Mammalian Chromatin

    Antoine H.F.M. Peters;Stefan Kubicek;Karl Mechtler;Roderick J. O'Sullivan

  • SET Domain-containing Protein, G9a, Is a Novel Lysine-preferring Mammalian Histone Methyltransferase with Hyperactivity and Specific Selectivity to Lysines 9 and 27 of Histone H3

    Makoto Tachibana;Kenji Sugimoto;Tatsunobu Fukushima;Yoichi Shinkai

  • Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9.

    Makoto Tachibana;Jun Ueda;Mikiko Fukuda;Naoki Takeda

  • Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET

    Toshiyuki Matsui;Danny Leung;Hiroki Miyashita;Irina A. Maksakova

  • H3K9 methyltransferase G9a and the related molecule GLP

    Yoichi Shinkai;Makoto Tachibana

  • Cellular dynamics associated with the genome-wide epigenetic reprogramming in migrating primordial germ cells in mice.

    Yoshiyuki Seki;Masashi Yamaji;Yukihiro Yabuta;Mitsue Sano

  • PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos

    Toshinobu Nakamura;Yu-Jung Liu;Hiroyuki Nakashima;Hiroki Umehara

  • G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription

    Makoto Tachibana;Yasuko Matsumura;Mikiko Fukuda;Hiroshi Kimura

  • Functional dynamics of H3K9 methylation during meiotic prophase progression

    Makoto Tachibana;Masami Nozaki;Naoki Takeda;Yoichi Shinkai

  • Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression

    Naoyuki Fujita;Sugiko Watanabe;Takaya Ichimura;Shu Tsuruzoe

  • Cloning of mice to six generations.

    Teruhiko Wakayama;Yoichi Shinkai;Kellie L. K. Tamashiro;Hiroyuki Niida

  • DNA methylation in ES cells requires the lysine methyltransferase G9a but not its catalytic activity

    Kevin B Dong;Irina A Maksakova;Irina A Maksakova;Fabio Mohn;Danny Leung

  • Epigenetic regulation of mouse sex determination by the histone demethylase Jmjd1a.

    Shunsuke Kuroki;Shogo Matoba;Mika Akiyoshi;Yasuko Matsumura

  • In Vitro and in Vivo Analyses of a Phe/Tyr Switch Controlling Product Specificity of Histone Lysine Methyltransferases

    Robert E. Collins;Makoto Tachibana;Hisashi Tamaru;Kristina M. Smith

  • Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling

    Yoko Hayashi-Takanaka;Kazuo Yamagata;Teruhiko Wakayama;Timothy J. Stasevich

  • Role of histone methyltransferase G9a in CpG methylation of the Prader-Willi syndrome imprinting center.

    Zhenghan Xin;Makoto Tachibana;Michele Guggiari;Edith Heard

  • DNA damage signaling triggers degradation of histone methyltransferases through APC/C(Cdh1) in senescent cells.

    Akiko Takahashi;Yoshinori Imai;Kimi Yamakoshi;Shinji Kuninaka

  • Obesity and metabolic syndrome in histone demethylase JHDM2a‐deficient mice

    Takeshi Inagaki;Makoto Tachibana;Kenta Magoori;Hiromi Kudo

  • A SECOND P53-RELATED PROTEIN, P73L, WITH HIGH HOMOLOGY TO P73

    Makoto Senoo;Naohiko Seki;Miki Ohira;Sumio Sugano

Frequent Co-Authors

Hiroshi Kimura
Hiroshi Kimura Tokyo Institute of Technology
Atsuo Ogura
Atsuo Ogura University of Tsukuba
Yasuhisa Matsui
Yasuhisa Matsui Tohoku University
Hiroyuki Sasaki
Hiroyuki Sasaki Kyushu University
Hiroshi Kimura
Hiroshi Kimura Tokyo Institute of Technology
Takeshi Urano
Takeshi Urano Shimane University
Tomohiro Kono
Tomohiro Kono Tokyo University of Agriculture
Dixie L. Mager
Dixie L. Mager University of British Columbia
Shin Yonehara
Shin Yonehara Kyoto University

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