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Yoichi Shinkai

Yoichi Shinkai

D-Index & Metrics

Molecular Biology

D-Index
77
Citations
33088
World Ranking
1096
National Ranking
88

Overview

Yoichi Shinkai is affiliated with RIKEN in Japan and conducts research primarily in the field of Biochemistry, Genetics, and Molecular Biology. Their work spans various subfields including Molecular Biology, Genetics, Public Health, Environmental and Occupational Health, Reproductive Medicine, and Oncology.

The scientist's research topics focus on:

  • Epigenetics and DNA Methylation
  • Cancer-related gene regulation
  • RNA modifications and cancer
  • Genomics and Chromatin Dynamics
  • CRISPR and Genetic Engineering
  • Sperm and Testicular Function
  • Reproductive Biology and Fertility

Frequent venues for Yoichi Shinkai's publications include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Research Square (Research Square)
  • Nucleic Acids Research
  • eLife

Some of their recent papers are:

  • "SETDB1-Mediated Silencing of Retroelements," 2020, Viruses
  • "The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes," 2021, Nature Communications
  • "DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency," 2021, Nature Communications
  • "Epigenetic plasticity safeguards heterochromatin configuration in mammals," 2023, Nucleic Acids Research
  • "Regulation of mammalian 3D genome organization and histone H3K9 dimethylation by H3K9 methyltransferases," 2021, Communications Biology

Yoichi Shinkai collaborates frequently with the following coauthors:

  • Kei Fukuda
  • Naoshi Dohmae
  • Takehiro Suzuki
  • Chikako Shimura
  • Tadahiro Shimazu

Best Publications

  • Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme

    Masamichi Muramatsu;Kazuo Kinoshita;Sidonia Fagarasan;Shuichi Yamada

  • RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

    Yoichi Shinkai;Gary Rathbun;Kong-Peng Lam;Eugene M. Oltz

  • G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis

    Makoto Tachibana;Kenji Sugimoto;Masami Nozaki;Jun Ueda

  • Partitioning and Plasticity of Repressive Histone Methylation States in Mammalian Chromatin

    Antoine H.F.M. Peters;Stefan Kubicek;Karl Mechtler;Roderick J. O'Sullivan

  • SET Domain-containing Protein, G9a, Is a Novel Lysine-preferring Mammalian Histone Methyltransferase with Hyperactivity and Specific Selectivity to Lysines 9 and 27 of Histone H3

    Makoto Tachibana;Kenji Sugimoto;Tatsunobu Fukushima;Yoichi Shinkai

  • Histone Methyltransferases Direct Different Degrees of Methylation to Define Distinct Chromatin Domains.

    Judd C. Rice;Scott D. Briggs;Beatrix Ueberheide;Cynthia M. Barber

  • Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9.

    Makoto Tachibana;Jun Ueda;Mikiko Fukuda;Naoki Takeda

  • Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET

    Toshiyuki Matsui;Danny Leung;Hiroki Miyashita;Irina A. Maksakova

  • G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis.

    Nirit Feldman;Ariela Gerson;Jia Fang;En Li

  • H3K9 methyltransferase G9a and the related molecule GLP

    Yoichi Shinkai;Makoto Tachibana

  • Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells

    Bo Wen;Hao Wu;Hao Wu;Yoichi Shinkai;Rafael A Irizarry;Rafael A Irizarry

  • De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes

    Silvina Epsztejn-Litman;Nirit Feldman;Monther Abu-Remaileh;Yoel Shufaro

  • DNA Methylation and SETDB1/H3K9me3 Regulate Predominantly Distinct Sets of Genes, Retroelements, and Chimeric Transcripts in mESCs

    Mohammad M. Karimi;Preeti Goyal;Irina A. Maksakova;Misha Bilenky

  • Cellular dynamics associated with the genome-wide epigenetic reprogramming in migrating primordial germ cells in mice.

    Yoshiyuki Seki;Masashi Yamaji;Yukihiro Yabuta;Mitsue Sano

  • PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos

    Toshinobu Nakamura;Yu-Jung Liu;Hiroyuki Nakashima;Hiroki Umehara

  • G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription

    Makoto Tachibana;Yasuko Matsumura;Mikiko Fukuda;Hiroshi Kimura

  • Functional dynamics of H3K9 methylation during meiotic prophase progression

    Makoto Tachibana;Masami Nozaki;Naoki Takeda;Yoichi Shinkai

  • Protein lysine methyltransferase G9a acts on non-histone targets

    Philipp Rathert;Arunkumar Dhayalan;Marie Murakami;Xing Zhang

  • Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression

    Naoyuki Fujita;Sugiko Watanabe;Takaya Ichimura;Shu Tsuruzoe

  • Genetic and epigenetic properties of mouse male germline stem cells during long-term culture

    Mito Kanatsu-Shinohara;Narumi Ogonuki;Tomohiko Iwano;Jiyoung Lee;Jiyoung Lee

Frequent Co-Authors

Makoto Tachibana
Makoto Tachibana Osaka University
Hiroshi Kimura
Hiroshi Kimura Tokyo Institute of Technology
Ko Okumura
Ko Okumura Juntendo University
Atsuo Ogura
Atsuo Ogura University of Tsukuba
Xing Zhang
Xing Zhang The University of Texas MD Anderson Cancer Center
Dixie L. Mager
Dixie L. Mager University of British Columbia
Hideo Yagita
Hideo Yagita Juntendo University
Albert Jeltsch
Albert Jeltsch University of Stuttgart
Hiroyuki Sasaki
Hiroyuki Sasaki Kyushu University

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