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Microbiology

D-Index
64
Citations
12614
World Ranking
2641
National Ranking
1066

Overview

Ju-Tao Guo is affiliated with Drexel University in the United States and has contributed extensively to the field of medical research, focusing primarily on infectious diseases and hepatology. Their research output reflects a concentration on viral pathogens such as hepatitis B virus (HBV), hepatitis C virus (HCV), and coronaviruses including SARS-CoV-2.

Guo's main fields of study encompass Medicine, with notable work in several subfields: Epidemiology, Hepatology, Infectious Diseases, Immunology, and Ecology. Within these areas, their research spans a variety of specialized topics including:

  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Interferon and immune responses
  • Bacteriophages and microbial interactions
  • Liver Disease Diagnosis and Treatment

Guo has authored papers in multiple prominent scientific journals. The frequent publication venues include:

  • Journal of Virology
  • Antiviral Research
  • PLoS Pathogens
  • Emerging Microbes & Infections
  • bioRxiv (Cold Spring Harbor Laboratory)

Some of Guo's recent publications reflect research on viral receptor usage, coronavirus entry mechanisms, and therapeutic targets for hepatitis B:

  • "Broad and Differential Animal Angiotensin-Converting Enzyme 2 Receptor Usage by SARS-CoV-2," 2020, Journal of Virology
  • "LY6E Restricts Entry of Human Coronaviruses, Including Currently Pandemic SARS-CoV-2," 2020, Journal of Virology
  • "Targeting the multifunctional HBV core protein as a potential cure for chronic hepatitis B," 2020, Antiviral Research
  • "Bat SARS-Like WIV1 coronavirus uses the ACE2 of multiple animal species as receptor and evades IFITM3 restriction via TMPRSS2 activation of membrane fusion," 2020, Emerging Microbes & Infections
  • "Prospects for the Global Elimination of Hepatitis B," 2021, Annual Review of Virology

Guo frequently collaborates with other researchers, with a number of co-authors contributing to many publications. These include:

  • Jinhong Chang
  • Yanming Du
  • Qiong Zhao
  • Xuesen Zhao
  • Xinglin Li

Best Publications

  • Inducible expression of human hepatitis B virus (HBV) in stably transfected hepatoblastoma cells: a novel system for screening potential inhibitors of HBV replication.

    Stephanie K. Ladner;Michael J. Otto;Christopher S. Barker;Katie Zaifert

  • Effect of Alpha Interferon on the Hepatitis C Virus Replicon

    Ju-Tao Guo;Vadim V. Bichko;Christoph Seeger

  • Identification of Five Interferon-Induced Cellular Proteins That Inhibit West Nile Virus and Dengue Virus Infections

    Dong Jiang;Jessica M. Weidner;Min Qing;Min Qing;Xiao Ben Pan

  • Characterization of the Intracellular Deproteinized Relaxed Circular DNA of Hepatitis B Virus: an Intermediate of Covalently Closed Circular DNA Formation

    Haitao Guo;Dong Jiang;Tianlun Zhou;Andrea Cuconati

  • Present and future therapies of hepatitis B: From discovery to cure

    T. Jake Liang;Timothy M. Block;Brian J. McMahon;Marc G. Ghany

  • Interferon-Induced Cell Membrane Proteins, IFITM3 and Tetherin, Inhibit Vesicular Stomatitis Virus Infection via Distinct Mechanisms

    Jessica M. Weidner;Dong Jiang;Xiao-Ben Pan;Jinhong Chang

  • Identification of Three Interferon-Inducible Cellular Enzymes That Inhibit the Replication of Hepatitis C Virus

    Dong Jiang;Haitao Guo;Chunxiao Xu;Jinhong Chang;Jinhong Chang

  • Liver-Specific MicroRNA miR-122 Enhances the Replication of Hepatitis C Virus in Nonhepatic Cells

    Jinhong Chang;Ju-Tao Guo;Dong Jiang;Haitao Guo

  • West Nile virus inhibits the signal transduction pathway of alpha interferon

    Ju-Tao Guo;Junpei Hayashi;Christoph Seeger

  • Replication of Hepatitis C Virus Subgenomes in Nonhepatic Epithelial and Mouse Hepatoma Cells

    Qing Zhu;Ju-Tao Guo;Christoph Seeger

  • Molecular virology of hepatitis B virus for clinicians.

    Timothy M. Block;Haitao Guo;Ju-Tao Guo

  • Identification of Disubstituted Sulfonamide Compounds as Specific Inhibitors of Hepatitis B Virus Covalently Closed Circular DNA Formation

    Dawei Cai;Courtney Mills;Wenquan Yu;Ran Yan

  • Inhibition of Hepatitis B Virus Replication by the Host Zinc Finger Antiviral Protein

    Richeng Mao;Hui Nie;Dawei Cai;Jiming Zhang

  • Apoptosis and regeneration of hepatocytes during recovery from transient hepadnavirus infections.

    Ju-Tao Guo;Huan Zhou;Chen Liu;Carol Aldrich

  • IFITM Genes, Variants, and Their Roles in the Control and Pathogenesis of Viral Infections

    Unknown

  • DNA Polymerase κ Is a Key Cellular Factor for the Formation of Covalently Closed Circular DNA of Hepatitis B Virus.

    Yonghe Qi;Zhenchao Gao;Guangwei Xu;Bo Peng

  • Interferon induction of IFITM proteins promotes infection by human coronavirus OC43.

    Xuesen Zhao;Fang Guo;Fei Liu;Andrea Cuconati

  • Sulfamoylbenzamide Derivatives Inhibit the Assembly of Hepatitis B Virus Nucleocapsids

    Matthew R. Campagna;Fei Liu;Richeng Mao;Courtney Mills

  • Alpha-interferon suppresses hepadnavirus transcription by altering epigenetic modification of cccDNA minichromosomes.

    Fei Liu;Matthew R Campagna;Yonghe Qi;Xuesen Zhao

  • Broad and Differential Animal Angiotensin-Converting Enzyme 2 Receptor Usage by SARS-CoV-2.

    Xuesen Zhao;Danying Chen;Robert Szabla;Mei Zheng

  • Metabolism and function of hepatitis B virus cccDNA: Implications for the development of cccDNA-targeting antiviral therapeutics

    Ju-Tao Guo;Haitao Guo

Frequent Co-Authors

Timothy M. Block
Timothy M. Block Drexel University
Anand Mehta
Anand Mehta Medical University of South Carolina
William S. Mason
William S. Mason Fox Chase Cancer Center
Wenhui Li
Wenhui Li Tsinghua University
Pei-Yong Shi
Pei-Yong Shi GlaxoSmithKline (United Kingdom)
Robert M. Moriarty
Robert M. Moriarty University of Illinois at Chicago
Fengmin Lu
Fengmin Lu Peking University
Sina Bavari
Sina Bavari United States Army Medical Research Institute of Infectious Diseases
Kyong-Mi Chang
Kyong-Mi Chang University of Pennsylvania
Terry D. Butters
Terry D. Butters University of Oxford

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