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David Durantel

David Durantel

D-Index & Metrics

Immunology

D-Index
54
Citations
11114
World Ranking
3883
National Ranking
181

Overview

David Durantel is affiliated with Inserm in France and has focused their research primarily in the field of Medicine, contributing to 121 publications. Their work spans several subfields including Epidemiology, Hepatology, Immunology, Infectious Diseases, and Molecular Biology. The main research topics covered by Durantel include Hepatitis B Virus Studies, Hepatitis C Virus Research, Liver Disease Diagnosis and Treatment, interferon and immune responses, Hepatitis Viruses Studies and Epidemiology, RNA modifications and cancer, and Viral Infections and Outbreaks Research.

Durantel has frequently published in these scientific venues:

  • Journal of Hepatology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Antiviral Research
  • JHEP Reports
  • Scientific Reports

Frequent coauthors associated with Durantel's research include Julie Lucifora, Anna Salvetti, Michel Rivoire, Caroline Pons, and Maud Michelet. These collaborations highlight an active engagement in multidisciplinary groups focused on viral hepatology and immunological responses.

Among Durantel's recent publications are:

  • "COVID-19: Discovery, diagnostics and drug development" (2020) in Journal of Hepatology
  • "Peripheral natural killer cells in chronic hepatitis B patients display multiple molecular features of T cell exhaustion" (2021) in eLife
  • "Restoration of RNA helicase DDX5 suppresses hepatitis B virus (HBV) biosynthesis and Wnt signaling in HBV-related hepatocellular carcinoma" (2020) in Theranostics
  • "RNA helicase DDX5 enables STAT1 mRNA translation and interferon signalling in hepatitis B virus replicating hepatocytes" (2021) in Gut
  • "Hepatitis B virus Core protein nuclear interactome identifies SRSF10 as a host RNA-binding protein restricting HBV RNA production" (2020) in PLoS Pathogens

The scientist's research contributions have covered viral pathogenesis, immune system interactions, and molecular mechanisms underlying hepatitis B virus replication and liver cancer development. Their work also touches on immune exhaustion and antiviral responses relevant to chronic hepatitis B infection.

Best Publications

  • Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases

    Lars Petter Jordheim;David Durantel;Fabien Zoulim;Charles Dumontet

  • Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA.

    Julie Lucifora;Yuchen Xia;Florian Reisinger;Ke Zhang

  • Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection

    Julie Lucifora;Silke Arzberger;David Durantel;David Durantel;David Durantel;Laura Belloni;Laura Belloni

  • COVID-19: Discovery, diagnostics and drug development.

    Tarik Asselah;David Durantel;Eric Pasmant;George Lau

  • Selection of a hepatitis B virus strain resistant to adefovir in a liver transplantation patient

    Jean-Pierre Villeneuve;David Durantel;Sandra Durantel;Christopher Westland

  • Susceptibility to antivirals of a human HBV strain with mutations conferring resistance to both lamivudine and adefovir.

    Marie-Noëlle Brunelle;Anne-Carole Jacquard;Christian Pichoud;David Durantel

  • Towards an HBV cure: state-of-the-art and unresolved questions—report of the ANRS workshop on HBV cure

    Mirjam B. Zeisel;Julie Lucifora;William S. Mason;Camille Sureau

  • New antiviral targets for innovative treatment concepts for hepatitis B virus and hepatitis delta virus

    David Durantel;Fabien Zoulim

  • Antiviral Therapies and Prospects for a Cure of Chronic Hepatitis B

    Fabien Zoulim;David Durantel

  • Persistence of the hepatitis B virus covalently closed circular DNA in HepaRG human hepatocyte-like cells.

    Olivier Hantz;Olivier Hantz;Romain Parent;Romain Parent;David Durantel;David Durantel;Philippe Gripon

  • A targeted functional RNA interference screen uncovers glypican 5 as an entry factor for hepatitis B and D viruses.

    Eloi R. Verrier;Che C. Colpitts;Charlotte Bach;Laura Heydmann

  • Study of the Mechanism of Antiviral Action of Iminosugar Derivatives against Bovine Viral Diarrhea Virus

    David Durantel;Norica Branza-Nichita;Sandra Carrouée-Durantel;Terry D. Butters

  • Control of hepatitis B virus replication by innate response of HepaRG cells

    Julie Lucifora;Julie Lucifora;David Durantel;David Durantel;David Durantel;Barbara Testoni;Barbara Testoni;Olivier Hantz;Olivier Hantz

  • Early inhibition of hepatocyte innate responses by hepatitis B virus

    Souphalone Luangsay;Marion Gruffaz;Marion Gruffaz;Nathalie Isorce;Nathalie Isorce;Barbara Testoni;Barbara Testoni

  • Receptor complementation and mutagenesis reveal SR-BI as an essential HCV entry factor and functionally imply its intra- and extra-cellular domains.

    Marlène Dreux;Viet Loan Dao Thi;Judith Fresquet;Maryse Guérin

  • Intrahepatic innate immune response pathways are downregulated in untreated chronic hepatitis B.

    Fanny Lebossé;Fanny Lebossé;Barbara Testoni;Barbara Testoni;Judith Fresquet;Judith Fresquet;Floriana Facchetti

  • The HepaRG cell line: biological properties and relevance as a tool for cell biology, drug metabolism, and virology studies.

    Marie-Jeanne Marion;Olivier Hantz;David Durantel;David Durantel

  • Hepatitis B Virus Requires Intact Caveolin-1 Function for Productive Infection in HepaRG Cells

    Alina Macovei;Cristina Radulescu;Catalin Lazar;Stefana Petrescu

  • Antiviral effect of N-butyldeoxynojirimycin against bovine viral diarrhea virus correlates with misfolding of E2 envelope proteins and impairment of their association into E1-E2 heterodimers.

    Norica Branza-Nichita;David Durantel;Sandra Carrouée-Durantel;Raymond A. Dwek

  • RNA helicase DEAD box protein 5 regulates Polycomb repressive complex 2/Hox transcript antisense intergenic RNA function in hepatitis B virus infection and hepatocarcinogenesis.

    Hao Zhang;Zheng Xing;Saravana Kumar Kailasam Mani;Brigitte Bancel

  • Case report Selection of a hepatitis B virus strain resistant to adefovir in a liver transplantation patient

    Jean-Pierre Villeneuve;David Durantel;Sandra Durantel;Christopher Westland

Frequent Co-Authors

Christian Trepo
Christian Trepo Hospices Civils de Lyon
Nicole Zitzmann
Nicole Zitzmann University of Oxford
Raymond A. Dwek
Raymond A. Dwek University of Oxford
Ulrike Protzer
Ulrike Protzer Technical University of Munich
François-Loïc Cosset
François-Loïc Cosset Claude Bernard University Lyon 1
Jean Dubuisson
Jean Dubuisson Institut Pasteur
Mathias Heikenwalder
Mathias Heikenwalder German Cancer Research Center

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