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Kathryn L. Penney

Kathryn L. Penney

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
10692
World Ranking
17079
National Ranking
7040

Overview

Kathryn L. Penney is affiliated with Harvard University in the United States and focuses primarily on research in medicine, biochemistry, genetics, and molecular biology. Their work frequently intersects with the fields of pulmonary and respiratory medicine, cancer research, genetics, oncology, and molecular biology.

The main topics of Kathryn L. Penney's research include prostate cancer treatment and research, prostate cancer diagnosis and treatment, cancer, lipids, and metabolism, genetic associations and epidemiology, molecular biology techniques and applications, statistical methods in clinical trials, and global cancer incidence and screening.

They have contributed to a variety of journals, with a notable number of publications appearing in:

  • Cancer Research
  • The Journal of Urology
  • Cancer Epidemiology Biomarkers & Prevention
  • Clinical Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)

Kathryn L. Penney has been involved in several recent papers, including:

  • Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction, 2021, Nature Genetics
  • An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk, 2020, Nature Communications
  • Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan, 2020, Nature Communications
  • Polygenic hazard score is associated with prostate cancer in multi-ethnic populations, 2021, Nature Communications
  • Evaluation of a Multiethnic Polygenic Risk Score Model for Prostate Cancer, 2021, JNCI Journal of the National Cancer Institute

Frequent co-authors collaborating with Kathryn L. Penney include:

  • Lorelei A. Mucci
  • Konrad H. Stopsack
  • Adam S. Kibel
  • Anna Plym
  • Jane B. Vaselkiv

The body of work demonstrates a strong focus on prostate cancer research, integrating genetic and molecular perspectives to better understand risk factors, mechanisms, and potential biomarkers. The combination of epidemiological studies and molecular biology techniques suggests an interdisciplinary approach within oncology and genetics.

Best Publications

  • Assessing the impact of population stratification on genetic association studies.

    Matthew L Freedman;Matthew L Freedman;David Reich;David Reich;Kathryn L Penney;Kathryn L Penney;Gavin J McDonald;Gavin J McDonald

  • Familial Risk and Heritability of Cancer Among Twins in Nordic Countries.

    Lorelei A Mucci;Lorelei A Mucci;Jacob B Hjelmborg;Jennifer R Harris;Kamila Czene

  • Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

    Fredrick R. Schumacher;Ali Amin Al Olama;Sonja I. Berndt;Sara Benlloch

  • Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men

    Matthew L. Freedman;Christopher A. Haiman;Nick Patterson;Gavin J. McDonald;Gavin J. McDonald

  • A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

    Ali Amin Al Olama;Zsofia Kote-Jarai;Sonja I. Berndt;David V. Conti

  • Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

    David V. Conti;Burcu F. Darst;Lilit C. Moss;Edward J. Saunders

  • The TMPRSS2:ERG Rearrangement, ERG Expression, and Prostate Cancer Outcomes: a Cohort Study and Meta-analysis

    Andreas Pettersson;Rebecca E. Graff;Scott R. Bauer;Michael J. Pitt

  • Transferability of tag SNPs in genetic association studies in multiple populations

    Paul I W de Bakker;Noël P Burtt;Robert R Graham;Candace Guiducci

  • An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk.

    Lang Wu;Yaohua Yang;Xingyi Guo;Xiao Ou Shu

  • The Heritability of Prostate Cancer in the Nordic Twin Study of Cancer

    Jacob von Bornemann Hjelmborg;Thomas Scheike;Klaus Holst;Axel Skytthe

  • Vitamin D–Related Genetic Variation, Plasma Vitamin D, and Risk of Lethal Prostate Cancer: A Prospective Nested Case–Control Study

    Irene M. Shui;Lorelei A. Mucci;Lorelei A. Mucci;Peter Kraft;Rulla M. Tamimi

  • mRNA Expression Signature of Gleason Grade Predicts Lethal Prostate Cancer

    Kathryn L. Penney;Jennifer A. Sinnott;Katja Fall;Yudi Pawitan

  • Vitamin D Receptor Protein Expression in Tumor Tissue and Prostate Cancer Progression

    Whitney K. Hendrickson;Richard Flavin;Julie L. Kasperzyk;Michelangelo Fiorentino

  • Fatty Acid Synthase Polymorphisms, Tumor Expression, Body Mass Index, Prostate Cancer Risk, and Survival

    Paul L. Nguyen;Jing Ma;Jorge E. Chavarro;Matthew L. Freedman

  • Common Genetic Variation in IGF1 and Prostate Cancer Risk in the Multiethnic Cohort

    Iona Cheng;Daniel O. Stram;Kathryn L. Penney;Malcolm Pike

  • Large-scale transcriptome-wide association study identifies new prostate cancer risk regions.

    Nicholas Mancuso;Simon Gayther;Alexander Gusev;Wei Zheng

  • A Large Multiethnic Genome-Wide Association Study of Prostate Cancer Identifies Novel Risk Variants and Substantial Ethnic Differences

    Thomas J. Hoffmann;Stephen K. Van Den Eeden;Stephen K. Van Den Eeden;Lori C. Sakoda;Eric Jorgenson

  • Association of Prostate Cancer Risk Variants with Gene Expression in Normal and Tumor Tissue

    Kathryn L. Penney;Kathryn L. Penney;Jennifer A. Sinnott;Jennifer A. Sinnott;Svitlana Tyekucheva;Travis Gerke

  • Evaluation of the 8q24 Prostate Cancer Risk Locus and MYC Expression

    Mark M. Pomerantz;Christine A. Beckwith;Meredith M. Regan;Stacia K. Wyman

  • Stromal and epithelial transcriptional map of initiation progression and metastatic potential of human prostate cancer

    Svitlana Tyekucheva;Michaela Bowden;Clyde Bango;Francesca Giunchi

Frequent Co-Authors

Lorelei A. Mucci
Lorelei A. Mucci Harvard University
Meir J. Stampfer
Meir J. Stampfer Harvard University
Massimo Loda
Massimo Loda Cornell University
David E. Neal
David E. Neal University of Cambridge
Janet L. Stanford
Janet L. Stanford Fred Hutchinson Cancer Research Center
Graham G. Giles
Graham G. Giles University of Melbourne
Johanna Schleutker
Johanna Schleutker Turku University Hospital
Kenneth W. Muir
Kenneth W. Muir University of Manchester
Rosalind A. Eeles
Rosalind A. Eeles Institute of Cancer Research
Matthew L. Freedman
Matthew L. Freedman Harvard University

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