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Microbiology

D-Index
65
Citations
15346
World Ranking
2503
National Ranking
187

Overview

Stephan Urban is affiliated with the University Hospital Heidelberg in Germany and primarily conducts research in the field of medicine, focusing on hepatology. Their work spans a range of subfields including hepatology, epidemiology, immunology, molecular biology, and infectious diseases.

The scientist's main research topics include:

  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • Hepatitis Viruses Studies and Epidemiology
  • Liver Disease Diagnosis and Treatment
  • Immune Cell Function and Interaction
  • interferon and immune responses
  • RNA Interference and Gene Delivery

Publication outlets frequently featuring their research are:

  • Journal of Hepatology
  • JHEP Reports
  • Viruses
  • Zeitschrift für Gastroenterologie
  • Gut

Stephan Urban has collaborated frequently with several coauthors, including:

  • Yi Ni
  • Maura Dandri
  • Bingqian Qu
  • Heiner Wedemeyer
  • Florian A. Lempp

Recent papers authored or coauthored by Stephan Urban include:

  • "Hepatitis D virus in 2021: virology, immunology and new treatment approaches for a difficult-to-treat disease" (2021, Gut)
  • "Safety and efficacy of bulevirtide in combination with tenofovir disoproxil fumarate in patients with hepatitis B virus and hepatitis D virus coinfection (MYR202): a multicentre, randomised, parallel-group, open-label, phase 2 trial" (2022, The Lancet Infectious Diseases)
  • "Stem cell-derived polarized hepatocytes" (2020, Nature Communications)
  • "48 weeks of high dose (10 mg) bulevirtide as monotherapy or with peginterferon alfa-2a in patients with chronic HBV/HDV co-infection" (2020, Journal of Hepatology)
  • "Therapeutic shutdown of HBV transcripts promotes reappearance of the SMC5/6 complex and silencing of the viral genome in vivo" (2021, Gut)

Best Publications

  • Infection of a human hepatoma cell line by hepatitis B virus

    Philippe Gripon;Sylvie Rumin;Stephan Urban;Jacques Le Seyec

  • Hepatitis B and D Viruses Exploit Sodium Taurocholate Co-transporting Polypeptide for Species-Specific Entry into Hepatocytes

    Yi Ni;Florian A. Lempp;Stefan Mehrle;Shirin Nkongolo

  • Hepatitis B virus infection initiates with a large surface protein-dependent binding to heparan sulfate proteoglycans.

    Andreas Schulze;Philippe Gripon;Stephan Urban

  • HBV DNA Integration: Molecular Mechanisms and Clinical Implications

    Thomas Tu;Magdalena A Budzinska;Nicholas A Shackel;Nicholas A Shackel;Stephan Urban

  • Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein.

    Joerg Petersen;Maura Dandri;Walter Mier;Marc Lütgehetmann

  • Efficient inhibition of hepatitis B virus infection by acylated peptides derived from the large viral surface protein.

    Philippe Gripon;Isabelle Cannie;Stephan Urban

  • Viral and cellular determinants involved in hepadnaviral entry

    Dieter Glebe;Stephan Urban

  • Treatment of chronic hepatitis D with the entry inhibitor myrcludex B: First results of a phase Ib/IIa study

    Pavel Bogomolov;Alexander Alexandrov;Natalia Voronkova;Maria Macievich

  • Strategies to inhibit entry of HBV and HDV into hepatocytes.

    Stephan Urban;Stephan Urban;Ralf Bartenschlager;Ralf Bartenschlager;Ralf Kubitz;Fabien Zoulim

  • The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus

    Tassilo Volz;Lena Allweiss;Mounira Ben MBarek;Michael Warlich

  • Present and future therapies of hepatitis B: From discovery to cure

    T. Jake Liang;Timothy M. Block;Brian J. McMahon;Marc G. Ghany

  • Mapping of the Hepatitis B Virus Attachment Site by Use of Infection-Inhibiting preS1 Lipopeptides and Tupaia Hepatocytes

    Dieter Glebe;Stephan Urban;Eva V Knoop;Nilgün Cag

  • Fine Mapping of Pre-S Sequence Requirements for Hepatitis B Virus Large Envelope Protein-Mediated Receptor Interaction

    Andreas Schulze;Alexa Schieck;Yi Ni;Walter Mier

  • Cyclosporin A inhibits hepatitis B and hepatitis D virus entry by cyclophilin-independent interference with the NTCP receptor

    Shirin Nkongolo;Yi Ni;Florian A. Lempp;Christina Kaufman

  • Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles.

    Thomas Tu;Magdalena A. Budzinska;Florian W. R. Vondran;Nicholas A. Shackel;Nicholas A. Shackel;Nicholas A. Shackel

  • Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation.

    Marc Lütgehetmann;Lida V. Mancke;Tassilo Volz;Martina Helbig

  • First-in-human application of the novel hepatitis B and hepatitis D virus entry inhibitor myrcludex B

    Antje Blank;Christoph Markert;Nicolas Hohmann;Alexandra Carls

  • Hepatitis D virus in 2021: virology, immunology and new treatment approaches for a difficult-to-treat disease.

    Stephan Urban;Christoph Neumann-Haefelin;Pietro Lampertico

  • Characterization of a hepatitis B and hepatitis delta virus receptor binding site

    Matthias Engelke;Kerry Mills;Stefan Seitz;Petra Simon

  • Proliferation of primary human hepatocytes and prevention of hepatitis B virus reinfection efficiently deplete nuclear cccDNA in vivo.

    Lena Allweiss;Tassilo Volz;Katja Giersch;Janine Kah

  • The replication cycle of hepatitis B virus

    Stephan Urban;Andreas Schulze;Maura Dandri;Joerg Petersen

  • Hepatitis B Virus infection initiates with a large surface protein-dependent binding to heparan sulfate proteoglycans

    A. Schulze;S. Seitz;P. Gripon;S. Urban

Frequent Co-Authors

Maura Dandri
Maura Dandri Universität Hamburg
Walter Mier
Walter Mier University Hospital Heidelberg
Marc Lütgehetmann
Marc Lütgehetmann University Medical Center Hamburg-Eppendorf
Ralf Bartenschlager
Ralf Bartenschlager Heidelberg University
Ulrike Protzer
Ulrike Protzer Technical University of Munich
Heiner Wedemeyer
Heiner Wedemeyer Hannover Medical School
Matthias Schwab
Matthias Schwab University of Tübingen
Peter Hans Hofschneider
Peter Hans Hofschneider Max Planck Society
Uwe Haberkorn
Uwe Haberkorn Heidelberg University
Ansgar W. Lohse
Ansgar W. Lohse Universität Hamburg

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