What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Biochemistry, Hepatocyte, Cell culture, Endocrinology and Internal medicine.
His work in Cytochrome P450, Drug metabolism, Constitutive androstane receptor, Pregnane X receptor and Microsome are all subfields of Biochemistry research.
André Guillouzo has included themes like Glutathione, Northern blot, Liver cytology, In vivo and Metabolism in his Hepatocyte study.
His In vivo study incorporates themes from Pharmacology and Cell biology.
His work carried out in the field of Cell culture brings together such families of science as CYP2B6, Gene expression, Cellular differentiation, Receptor and Cytochrome.
His Endocrinology study combines topics from a wide range of disciplines, such as Fetus and Bile Salt Export Pump.
His most cited work include:
- Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies (590 citations)
- Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma heparg cells (495 citations)
- Maintenance and reversibility of active albumin secretion by adult rat hepatocytes co-cultured with another liver epithelial cell type. (472 citations)
What are the main themes of his work throughout his whole career to date?
Biochemistry, Hepatocyte, Molecular biology, Pharmacology and Cell culture are his primary areas of study.
Cytochrome P450, Enzyme, Drug metabolism, Glutathione and Microsome are the primary areas of interest in his Biochemistry study.
His Hepatocyte research includes themes of Internal medicine, Endocrinology, Metabolism and Liver cytology.
Protein subunit is closely connected to Northern blot in his research, which is encompassed under the umbrella topic of Molecular biology.
His Pharmacology study integrates concerns from other disciplines, such as CYP3A4, Cholestasis, Toxicity and Cytotoxicity.
Within one scientific family, André Guillouzo focuses on topics pertaining to In vivo under In vitro, and may sometimes address concerns connected to Cell biology.
He most often published in these fields:
- Biochemistry (43.10%)
- Hepatocyte (32.47%)
- Molecular biology (30.17%)
What were the highlights of his more recent work (between 2011-2020)?
- Pharmacology (25.86%)
- Cholestasis (12.36%)
- Bile acid (8.05%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Pharmacology, Cholestasis, Bile acid, Biochemistry and Efflux.
The Pharmacology study combines topics in areas such as CYP3A4, In vitro, Cytotoxicity and Toxicity.
Internal medicine and Endocrinology are closely tied to his Cholestasis research.
His Biochemistry research incorporates themes from Cell culture and Cell biology.
As part of one scientific family, André Guillouzo deals mainly with the area of Efflux, narrowing it down to issues related to the Oxidative stress, and often Reactive oxygen species and Endoplasmic reticulum.
His work in Hepatocyte covers topics such as Multidrug resistance-associated protein 2 which are related to areas like Bile canaliculus.
Between 2011 and 2020, his most popular works were:
- Optimization of the HepaRG cell model for drug metabolism and toxicity studies (111 citations)
- Optimization of the HepaRG cell model for drug metabolism and toxicity studies (111 citations)
- Oxidative stress plays a major role in chlorpromazine‐induced cholestasis in human HepaRG cells (96 citations)
In his most recent research, the most cited papers focused on:
His scientific interests lie mostly in Bile acid, Biochemistry, Cholestasis, Efflux and Cell culture.
His Biochemistry study frequently links to other fields, such as Pharmacology.
The study incorporates disciplines such as Myosin light-chain kinase and Rho-associated protein kinase in addition to Cholestasis.
His studies deal with areas such as Oxidative stress, Endocrinology, Bone canaliculus, Reactive oxygen species and Bile Salt Export Pump as well as Efflux.
His Endocrinology study deals with Troglitazone intersecting with Lipid metabolism and Transcriptome.
His research investigates the connection between Cell culture and topics such as Drug metabolism that intersect with issues in In vitro, Phospholipidosis, Cellular differentiation, CYP3A4 and Toxicity.
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