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Biology and Biochemistry
France
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
82
Citations
23319
World Ranking
3715
National Ranking
93

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in France Leader Award

Overview

Patrick Maurel is affiliated with the University of Montpellier in France. Their research activities primarily focus on the field of Chemistry, with a particular emphasis on Organic Chemistry. The scientist's work explores specific areas including Carbohydrate Chemistry and Synthesis, Synthesis and Biological Evaluation, and Synthesis and Biological Activity.

The scientist has contributed to recent scholarly publications, including the paper titled Glucose-based spiro-oxathiazoles as in vivo anti-hyperglycemic agents through glycogen phosphorylase inhibition, published in 2020 by Organic & Biomolecular Chemistry.

Frequent co-authors collaborating with Patrick Maurel include:

  • David Goyard
  • Bálint Kónya
  • Katalin Czifrák
  • Paolo Larini
  • Fanny Demontrond

Scientific contributions have been disseminated mainly through journals such as:

  • Organic & Biomolecular Chemistry

Research topics addressed by Patrick Maurel encompass:

  • Carbohydrate Chemistry and Synthesis
  • Synthesis and Biological Evaluation
  • Synthesis and Biological Activity

Best Publications

  • Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression.

    Peter Kuehl;Jiong Zhang;Yvonne Lin;Jatinder Lamba

  • Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies

    Nicola J. Hewitt;Maria Jose Gomez Lechon;J. Brian Houston;David Hallifax

  • Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes.

    L Pichard;I Fabre;G Fabre;J Domergue

  • Identification of an inducible form of cytochrome P-450 in human liver

    P B Watkins;S A Wrighton;P Maurel;E G Schuetz

  • Metabolism of cyclosporin A. IV: Purification and identification of the rifampicin-inducible human liver cytochrome P-450 (cyclosporin A oxidase) as a product of P450IIIA gene subfamily

    J Combalbert;I Fabre;G Fabre;I Dalet

  • Expression of CYP3A4, CYP2B6, andCYP2C9 Is Regulated by the Vitamin D Receptor Pathway in Primary Human Hepatocytes

    Lionel Drocourt;Jean-Claude Ourlin;Jean-Marc Pascussi;Patrick Maurel

  • Induction of CYP2C genes in human hepatocytes in primary culture.

    Sabine Gerbal-Chaloin;Jean-Marc Pascussi;Lydiane Pichard-Garcia;Martine Daujat

  • Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes

    Jean‐Marc Pascussi;Lionel Drocourt;Sabine Gerbal‐Chaloin;Jean‐Michel Fabre

  • Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators.

    Jean-Marc Pascussi;Lionel Drocourt;Jean-Michel Fabre;Patrick Maurel

  • The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors

    J.M. Pascussi;S. Gerbal-Chaloin;L. Drocourt;P. Maurel

  • The increase in urinary excretion of 6 beta-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction.

    C Ged;JM Rouillon;L Pichard;J Combalbert

  • The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants.

    Jiong Zhang;Peter Kuehl;Eric D. Green;Jeffery W. Touchman

  • Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p

    Steven A. Wrighton;Patrick Maurel;Erin G. Schuetz;Paul B. Watkins

  • The low-density lipoprotein receptor plays a role in the infection of primary human hepatocytes by hepatitis C virus.

    Sonia Molina;Valérie Castet;Valérie Castet;Chantal Fournier-Wirth;Chantal Fournier-Wirth;Lydiane Pichard-Garcia;Lydiane Pichard-Garcia

  • Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450

    Dominique Diaz;Isabelle Fabrev;Martine Daujat;Bernard Saint Aubert

  • Possible involvement of pregnane X receptor-enhanced CYP24 expression in drug-induced osteomalacia.

    Jean Marc Pascussi;Agnes Robert;Minh Nguyen;Odile Walrant-Debray

  • Differential effects of cytokines on the inducible expression of CYP1A1, CYP1A2, and CYP3A4 in human hepatocytes in primary culture.

    Jordi Muntané‐Relat;Jean‐Claude Ourlin;Jacques Domergue;Patrick Maurel

  • Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor.

    Sabine Gerbal-Chaloin;Martine Daujat;Jean-Marc Pascussi;Lydiane Pichard-Garcia

  • The Tangle of Nuclear Receptors that Controls Xenobiotic Metabolism and Transport: Crosstalk and Consequences

    Jean-Marc Pascussi;Sabine Gerbal-Chaloin;Cédric Duret;Martine Daujat-Chavanieu

  • Interleukin-6 negatively regulates the expression of pregnane X receptor and constitutively activated receptor in primary human hepatocytes.

    Jean-Marc Pascussi;Sabine Gerbal-Chaloin;Lydiane Pichard-Garcia;Martine Daujat

Frequent Co-Authors

Jean-Marc Pascussi
Jean-Marc Pascussi University of Montpellier
Jitka Ulrichová
Jitka Ulrichová Palacký University, Olomouc
Dominique Larrey
Dominique Larrey University of Montpellier
Claude Balny
Claude Balny University of Montpellier
Steven A. Wrighton
Steven A. Wrighton Eli Lilly (United States)
Erin G. Schuetz
Erin G. Schuetz St. Jude Children's Research Hospital
Philip S. Guzelian
Philip S. Guzelian University of Colorado Anschutz Medical Campus
Philippe Beaune
Philippe Beaune Université Paris Cité
Jane A. McKeating
Jane A. McKeating University of Oxford
Arti Ahluwalia
Arti Ahluwalia University of Pisa

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