What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Biochemistry, Cytochrome P450, Pregnane X receptor, Pharmacology and Constitutive androstane receptor.
His biological study spans a wide range of topics, including Cyclosporin a, Microsome, Cytochrome, Isozyme and In vivo.
His Pregnane X receptor research is multidisciplinary, relying on both Calcitriol receptor, Receptor, Retinoid X receptor alpha and Nucleic acid sequence.
Patrick Maurel regularly ties together related areas like Enzyme inducer in his Pharmacology studies.
His study in Constitutive androstane receptor is interdisciplinary in nature, drawing from both Estrogen-related receptor gamma, Glucocorticoid receptor and Cell biology.
His Enzyme research incorporates themes from Cell, Drug development and Transporter.
His most cited work include:
- Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. (1770 citations)
- Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies (590 citations)
- Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies (590 citations)
What are the main themes of his work throughout his whole career to date?
Patrick Maurel spends much of his time researching Biochemistry, Molecular biology, Cytochrome P450, Pharmacology and Pregnane X receptor.
His Biochemistry research focuses on subjects like In vivo, which are linked to In vitro.
His research on Molecular biology also deals with topics like
- Hepatocyte which intersects with area such as Cellular differentiation,
- Messenger RNA that connect with fields like Inducer.
Patrick Maurel combines subjects such as Glutathione, Enzyme inducer and Drug metabolism with his study of Cytochrome P450.
In his research, CYP1A2 is intimately related to CYP3A4, which falls under the overarching field of Pharmacology.
His study on Pregnane X receptor also encompasses disciplines like
- Constitutive androstane receptor which intersects with area such as Glucocorticoid receptor,
- Receptor, which have a strong connection to Xenobiotic.
He most often published in these fields:
- Biochemistry (32.63%)
- Molecular biology (30.08%)
- Cytochrome P450 (21.19%)
What were the highlights of his more recent work (between 2010-2020)?
- Molecular biology (30.08%)
- Hepatocyte (19.92%)
- Biochemistry (32.63%)
In recent papers he was focusing on the following fields of study:
Patrick Maurel mainly focuses on Molecular biology, Hepatocyte, Biochemistry, Pregnane X receptor and Virology.
His Molecular biology research includes themes of Progenitor cell, Xenobiotic, Glutathione and Cytochrome P450.
His Hepatocyte study incorporates themes from Hepatitis B and Liver transplantation.
His work on Glycogen phosphorylase, Enzyme and Xenobiotic metabolizing enzymes as part of general Biochemistry study is frequently linked to Context and Seeding, bridging the gap between disciplines.
Patrick Maurel has researched Pregnane X receptor in several fields, including Aryl hydrocarbon receptor, Gene expression and Constitutive androstane receptor.
The Virology study combines topics in areas such as Cell culture, Internal medicine, Hepatology and Genotype.
Between 2010 and 2020, his most popular works were:
- Modular bioreactor for primary human hepatocyte culture: Medium flow stimulates expression and activity of detoxification genes (77 citations)
- Modular bioreactor for primary human hepatocyte culture: Medium flow stimulates expression and activity of detoxification genes (77 citations)
- Replication of Hepatitis C Virus Genotype 3a in Cultured Cells (48 citations)
In his most recent research, the most cited papers focused on:
His primary scientific interests are in Molecular biology, Hepatocyte, Constitutive androstane receptor, Biochemistry and Aryl hydrocarbon receptor.
His research integrates issues of Xenobiotic, Glutathione, Cytochrome P450 and Drug metabolism in his study of Molecular biology.
His Hepatocyte study combines topics in areas such as Embryonic stem cell, Cellular differentiation, Progenitor cell, Stem cell and Hepatocyte nuclear factor 4.
By researching both Constitutive androstane receptor and Liver cytology, he produces research that crosses academic boundaries.
Biochemistry and Context are two areas of study in which Patrick Maurel engages in interdisciplinary research.
His work deals with themes such as CYP3A4, Nuclear receptor, Pregnane X receptor, Regulation of gene expression and LRP6, which intersect with Aryl hydrocarbon receptor.
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