World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
91
Citations
29456
World Ranking
2326
National Ranking
1244

Steven A. Wrighton publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Steven A. Wrighton sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 184 publications — 43rd percentile

43% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Steven A. Wrighton D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Steven A. Wrighton sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 91 D-Index — 88th percentile

88% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Steven A. Wrighton is affiliated with Eli Lilly in the United States and has contributed extensively to the field of chemical and pharmaceutical sciences. Their research spans several interconnected areas including computational drug discovery methods, pharmacogenetics and drug metabolism, and various aspects of molecular biology and physiology.

The scientist's publication record includes notable papers such as:

  • Glossary and tutorial of xenobiotic metabolism terms used during small molecule drug discovery and development (IUPAC Technical Report), 2021, Pure and Applied Chemistry
  • 191 Reactive Intermediates, 2022, IUPAC Standards Online
  • 20 Aromatic Hydrocarbon Receptor (Ahr), 2022, IUPAC Standards Online
  • 36 Catechol-O-Methyl Transferase (Comt), 2022, IUPAC Standards Online
  • 158 Organic Cation Transporters (Octs), 2022, IUPAC Standards Online

These publications reflect a focus on biochemistry and drug metabolism, with several appearing in IUPAC Standards Online, a frequent publication venue for Wrighton. The scientist has contributed 241 publications to this platform, alongside work published in Pure and Applied Chemistry.

The scientist's collaborative network includes frequent coauthors such as Paul Erhardt, Kenneth Bachmann, Donald Birkett, Michael Boberg, and Nicholas Bodor. These collaborations have supported research outputs primarily in pharmacological and biochemical contexts.

Wrighton's subfields of study cover:

  • Computational Theory and Mathematics
  • Molecular Biology
  • Pharmacology
  • Physiology
  • Pharmaceutical Science

The major topics addressed in their research are:

  • Computational Drug Discovery Methods
  • Pharmacogenetics and Drug Metabolism
  • Chemical Reactions and Isotopes
  • Diet and Metabolism Studies
  • Metabolism and Genetic Disorders
  • Cancer, Hypoxia, and Metabolism
  • Amino Acid Enzymes and Metabolism

This profile highlights Steven A. Wrighton's engagement with scientific topics that bridge computational approaches and experimental biology, emphasizing molecular mechanisms influencing drug metabolism and related biochemical processes.

Best Publications

  • Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression.

    Peter Kuehl;Jiong Zhang;Yvonne Lin;Jatinder Lamba

  • The human hepatic cytochromes P450 involved in drug metabolism.

    Steven A. Wrighton;Jeffrey C. Stevens

  • The conduct of in vitro and in vivo drug-drug interaction studies: A Pharmaceutical Research and Manufacturers of America (PhRMA) perspective

    Thorir D. Bjornsson;John T. Callaghan;Heidi J. Einolf;Volker Fischer

  • Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man.

    P B Watkins;S A Wrighton;E G Schuetz;D T Molowa

  • Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs.

    D Wang;Y Guo;S A Wrighton;G E Cooke

  • Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7.

    J. Andrew Williams;Barbara J. Ring;Barbara J. Ring;Varon E. Cantrell;Varon E. Cantrell;David R. Jones

  • Studies on the expression and metabolic capabilities of human liver cytochrome P450IIIA5 (HLp3)

    S A Wrighton;W R Brian;M A Sari;M Iwasaki

  • CYP3A gene expression in human gut epithelium.

    Joseph C. Kolars;Kenneth S. Lown;Phyllissa Schmiedlin-Ren;Mita Ghosh

  • Metabolism and disposition of the thienopyridine antiplatelet drugs ticlopidine, clopidogrel, and prasugrel in humans.

    Nagy A. Farid;Atsushi Kurihara;Steven A. Wrighton

  • Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily.

    J C Gorski;S D Hall;D R Jones;M VandenBranden

  • Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450. Studies in rats and patients.

    P B Watkins;S A Murray;L G Winkelman;D M Heuman

  • Identification of an inducible form of cytochrome P-450 in human liver

    P B Watkins;S A Wrighton;P Maurel;E G Schuetz

  • Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression.

    Vishal Lamba;Jatinder Lamba;Kazuto Yasuda;Stephen Strom

  • Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test.

    K S Lown;J C Kolars;K E Thummel;J L Barnett

  • In vitro glucuronidation using human liver microsomes and the pore-forming peptide alamethicin.

    Michael B. Fisher;Kristina Campanale;Bradley L. Ackermann;Mark VandenBranden

  • THE ROLE OF HEPATIC AND EXTRAHEPATIC UDP-GLUCURONOSYLTRANSFERASES IN HUMAN DRUG METABOLISM *,†

    Michael B. Fisher;Mary F. Paine;Timothy J. Strelevitz;Steven A. Wrighton

  • The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants.

    Jiong Zhang;Peter Kuehl;Eric D. Green;Jeffery W. Touchman

  • Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p

    Steven A. Wrighton;Patrick Maurel;Erin G. Schuetz;Paul B. Watkins

  • Isolation and characterization of human liver cytochrome P450 2C19 : correlation between 2C19 and S-mephenytoin 4'-hydroxylation

    S.A. Wrighton;J.C. Stevens;G.W. Becker;M. Vandenbranden

  • INTERACTIONS OF TWO MAJOR METABOLITES OF PRASUGREL, A THIENOPYRIDINE ANTIPLATELET AGENT, WITH THE CYTOCHROMES P450

    Jessica L. Fayer Rehmel;James A. Eckstein;Nagy A. Farid;John B. Heim

Frequent Co-Authors

Jacqueline F. Sinclair
Jacqueline F. Sinclair Dartmouth College
Peter R. Sinclair
Peter R. Sinclair Dartmouth College
Paul B. Watkins
Paul B. Watkins University of North Carolina at Chapel Hill
Sean Ekins
Sean Ekins University of Arizona
Erin G. Schuetz
Erin G. Schuetz St. Jude Children's Research Hospital
Philip S. Guzelian
Philip S. Guzelian University of Colorado Anschutz Medical Campus
Stephen C. Strom
Stephen C. Strom Karolinska Institute
Kenneth E. Thummel
Kenneth E. Thummel University of Washington
Elizabeth H. Jeffery
Elizabeth H. Jeffery University of Illinois at Urbana-Champaign
Frank J. Gonzalez
Frank J. Gonzalez National Institutes of Health

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