World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
104
Citations
48814
World Ranking
6960
National Ranking
3664

Leslie Z. Benet publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Leslie Z. Benet sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 634 publications — 75th percentile

75% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Leslie Z. Benet D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Leslie Z. Benet sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 104 D-Index — 66th percentile

66% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Research.com Recognitions

  • 1987 - Member of the National Academy of Medicine (NAM)
  • 1978 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Leslie Z. Benet is affiliated with the University of California, San Francisco in the United States. Their research primarily spans the fields of Medicine and Pharmacology, Toxicology and Pharmaceutics, with extensive work in subfields such as Pharmacology, Oncology, Pediatrics, Perinatology and Child Health, Statistics and Probability, and Immunology.

The scientist's work has contributed notably to several research topics, including:

  • Pharmacogenetics and Drug Metabolism
  • Drug Transport and Resistance Mechanisms
  • Pharmacological Effects and Toxicity Studies
  • Statistical Methods in Clinical Trials
  • Biosimilars and Bioanalytical Methods
  • Analytical Chemistry and Chromatography
  • Drug-Induced Hepatotoxicity and Protection

Leslie Z. Benet has published extensively in various scientific journals. Frequent publication venues include:

  • The AAPS Journal
  • Pharmaceutical Research
  • Drug Metabolism and Disposition
  • Clinical Pharmacology & Therapeutics
  • Drug Metabolism and Pharmacokinetics

Selected recent papers illustrate the thematic focus and evolution of their research:

  • "The Critical Role of Passive Permeability in Designing Successful Drugs," 2020, ChemMedChem
  • "Successful and Unsuccessful Prediction of Human Hepatic Clearance for Lead Optimization," 2021, Journal of Medicinal Chemistry
  • "Late-Stage Failures of Monoclonal Antibody Drugs: A Retrospective Case Study Analysis," 2020, Pharmacology
  • "State of the Art and Uses for the Biopharmaceutics Drug Disposition Classification System (BDDCS): New Additions, Revisions, and Citation References," 2022, The AAPS Journal
  • "Are There Any Experimental Perfusion Data that Preferentially Support the Dispersion and Parallel-Tube Models over the Well-Stirred Model of Organ Elimination?," 2020, Drug Metabolism and Disposition

The scientist has collaborated regularly with several coauthors, including Jasleen K. Sodhi, Yue Xiang, Shuaibing Liu, Wei Liu, and Suodi Zhai. Notably, collaboration with Jasleen K. Sodhi stands out with a higher number of joint works.

Leslie Z. Benet has received professional recognition by being named a Member of the National Academy of Medicine in 1987 and as a Fellow of the American Association for the Advancement of Science in 1978.

Best Publications

  • Membrane transporters in drug development.

    Kathleen M. Giacomini;Shiew Mei Huang;Donald J. Tweedie;Leslie Z. Benet

  • Predicting Drug Disposition via Application of BCS: Transport/Absorption/ Elimination Interplay and Development of a Biopharmaceutics Drug Disposition Classification System

    Chi-Yuan Wu;Leslie Z. Benet

  • Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

    Vincent J. Wacher;Chi‐Yuan Wu;Leslie Z. Benet

  • Clearance concepts in pharmacokinetics

    Malcolm Rowland;Leslie Z. Benet;Garry G. Graham

  • Changes in plasma protein binding have little clinical relevance.

    Leslie Z. Benet;Betty‐Ann Hoener

  • Role of intestinal P‐glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine

    Kenneth S. Lown;Kenneth S. Lown;Robert R. Mayo;Robert R. Mayo;Alan B. Leichtman;Alan B. Leichtman;Hsiu Ling Hsiao;Hsiu Ling Hsiao

  • BDDCS, the Rule of 5 and drugability.

    Leslie Z. Benet;Chelsea M. Hosey;Oleg Ursu;Tudor I. Oprea

  • The gut as a barrier to drug absorption: combined role of cytochrome P450 3A and P-glycoprotein.

    Yuanchao Zhang;Leslie Z. Benet

  • BDDCS Applied to Over 900 Drugs

    Leslie Z. Benet;Fabio Broccatelli;Fabio Broccatelli;Tudor I. Oprea;Tudor I. Oprea

  • Gender Effects in Pharmacokinetics and Pharmacodynamics

    Robert Z. Harris;Leslie Z. Benet;Janice B. Schwartz

  • Role of P‐glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics

    Vincent J. Wacher;Jeffrey A. Silverman;Yuanchao Zhang;Leslie Z. Benet

  • Acyl glucuronides revisited: is the glucuronidation process a toxification as well as a detoxification mechanism?

    Spahn-Langguth H;Benet Lz

  • PREDICTING DRUG DISPOSITION, ABSORPTION / ELIMINATION / TRANSPORTER INTERPLAY AND THE ROLE OF FOOD ON DRUG ABSORPTION

    Joseph M. Custodio;Chi-Yuan Wu;Leslie Z. Benet

  • The Role of Transporters in the Pharmacokinetics of Orally Administered Drugs

    Sarah Shugarts;Leslie Z. Benet

  • Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction.

    Mary F Hebert;John P Roberts;Thomayant Prueksaritanont;Leslie Z Benet

  • Active secretion and enterocytic drug metabolism barriers to drug absorption

    Vincent J. Wacher;Laurent Salphati;Leslie Z. Benet

  • effect of OATP1B transporter inhibition on the pharmacokinetics of atorvastatin in healthy volunteers.

    Y Y Lau;Y Huang;L Frassetto;L Z Benet

  • Opportunities for Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development

    Carl C. Peck;William H. Barr;Leslie Z. Benet;Jerry Collins

  • Mechanisms of clinically relevant drug interactions associated with tacrolimus.

    Uwe Christians;Uwe Christians;Wolfgang Jacobsen;Leslie Z. Benet;Alfonso Lampen

  • Unmasking the Dynamic Interplay between Intestinal P-Glycoprotein and CYP3A4

    Carolyn L. Cummins;Wolfgang Jacobsen;Leslie Z. Benet

Frequent Co-Authors

Uwe Christians
Uwe Christians University of Colorado Anschutz Medical Campus
Gerhard Levy
Gerhard Levy University at Buffalo, State University of New York
Abraham M. Rudolph
Abraham M. Rudolph University of California, San Francisco
Dieter Leibfritz
Dieter Leibfritz University of Bremen
Gordon L. Amidon
Gordon L. Amidon University of Michigan–Ann Arbor
Gerald J. Berry
Gerald J. Berry Stanford University
Alma L. Burlingame
Alma L. Burlingame University of California, San Francisco
John P. Roberts
John P. Roberts University of California, San Francisco
Jerry M. Collins
Jerry M. Collins National Institutes of Health
Malcolm Rowland
Malcolm Rowland University of Manchester

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