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Medicine

D-Index
92
Citations
32913
World Ranking
11262
National Ranking
5781

Research.com Recognitions

  • 1985 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

William J. Jusko is affiliated with the University at Buffalo, State University of New York in the United States. Their research primarily focuses on the field of Medicine, with significant contributions to Pharmacology, Molecular Biology, Oncology, Endocrinology, Diabetes and Metabolism, and Neurology.

The scientist's work addresses several main topics, including:

  • Pharmacogenetics and Drug Metabolism
  • Drug Transport and Resistance Mechanisms
  • Hormonal Regulation and Hypertension
  • Antibiotics Pharmacokinetics and Efficacy
  • Statistical Methods in Clinical Trials
  • Hormonal and reproductive studies
  • Pharmacological Effects and Toxicity Studies

William J. Jusko has published extensively in several frequent venues, reflecting the diversity and depth of their research. These venues include:

  • Drug Metabolism and Disposition
  • Journal of Pharmacology and Experimental Therapeutics
  • The Journal of Clinical Pharmacology
  • Journal of Pharmacokinetics and Pharmacodynamics
  • The AAPS Journal

The scientist has collaborated regularly with a group of frequent coauthors, indicating ongoing research partnerships. These include:

  • Yoo-Seong Jeong
  • Xiao-Nan Li
  • Debra C. DuBois
  • Richard R. Almon
  • Ruihong Yu

Recent papers authored by William J. Jusko cover diverse aspects of pharmacokinetics and pharmacodynamics. Among these are:

  • "Transitioning from Basic toward Systems Pharmacodynamic Models: Lessons from Corticosteroids," 2020, published in Pharmacological Reviews
  • "Meta-Assessment of Metformin Absorption and Disposition Pharmacokinetics in Nine Species," 2021, published in Pharmaceuticals
  • "Physiologically Based Pharmacokinetics of Dexamethasone in Rats," 2020, published in Drug Metabolism and Disposition
  • "Population pharmacokinetic modeling of intramuscular and oral dexamethasone and betamethasone in Indian women," 2021, published in Journal of Pharmacokinetics and Pharmacodynamics
  • "Assessing Liver-to-Plasma Partition Coefficients and In Silico Calculation Methods: When Does the Hepatic Model Matter in PBPK?," 2022, published in Drug Metabolism and Disposition

In 1985, William J. Jusko was recognized as a Fellow of the American Association for the Advancement of Science (AAAS), reflecting their standing within the scientific community.

Best Publications

  • Comparison of four basic models of indirect pharmacodynamic responses

    Natalie L. Dayneka;Natalie L. Dayneka;Varun Garg;William J. Jusko

  • General pharmacokinetic model for drugs exhibiting target-mediated drug disposition.

    Donald E. Mager;William J. Jusko

  • Plasma and Tissue Protein Binding of Drugs in Pharmacokinetics

    William J. Jusko;Mark Gretch

  • Applied pharmacokinetics : principles of therapeutic drug monitoring

    William E. Evans;Jerome J. Schentag;William J. Jusko

  • Physiologic indirect response models characterize diverse types of pharmacodynamic effects

    William J Jusko;Hui C Ko

  • Diversity of Mechanism-Based Pharmacodynamic Models

    Donald E. Mager;Elzbieta Wyska;William J. Jusko

  • Consensus document: therapeutic monitoring of tacrolimus (FK-506).

    William J. Jusko;Angus W. Thomson;John Fung;Paul McMaster

  • Factors affecting theophylline clearances: Age, tobacco, marijuana, cirrhosis, congestive heart failure, obesity, oral contraceptives, benzodiazepines, barbiturates, and ethanol

    William J. Jusko;Mark J. Gardner;Antoinette Mangione;Jerome J. Schentag

  • Effect of smoking on theophylline disposition.

    Susan N. Hunt;William J. Jusko;Anthony M. Yurchak

  • Introduction of a Composite Parameter to the Pharmacokinetics of Venlafaxine and its Active O‐Desmethyl Metabolite

    Karen J. Klamerus;Kathleen Moloney;Richard L. Rudolph;Samuel F. Sisenwine

  • Pharmacokinetics of tacrolimus in liver transplant patients.

    William J. Jusko;Wojciech Piekoszewski;Goran B. Klintmalm;Mark S. Shaefer

  • Dose dependent pharmacokinetics of prednisone and prednisolone in man

    James Q. Rose;Anthony M. Yurchak;William J. Jusko

  • Characteristics of indirect pharmacodynamic models and applications to clinical drug responses.

    Amarnath Sharma;Amarnath Sharma;William J. Jusko

  • Gender‐based effects on methylprednisolone pharmacokinetics and pharmacodynamics

    Kim H Lew;Kim H Lew;Elizabeth A Ludwig;Elizabeth A Ludwig;Mark A Milad;Mark A Milad;Kathleen Donovan;Kathleen Donovan

  • Transit Compartments versus Gamma Distribution Function To Model Signal Transduction Processes in Pharmacodynamics

    Yu-Nien Sun;William J. Jusko

  • Factors affecting the absorption of riboflavin in man.

    Gerhard Levy;William J. Jusko

  • Corticosteroid analysis in biological fluids by high-performance liquid chromatography

    James Q. Rose;William J. Jusko

  • Enhanced biotransformation of theophylline in marihuana and tobacco smokers

    William J. Jusko;Jerome J. Schentag;John H. Clark;Mark Gardner

  • Fluid Shifts and Other Factors Affecting Plasma Protein Binding of Prednisolone by Equilibrium Dialysis

    F. Douglas Boudinot;William J. Jusko

  • Role of tobacco smoking in pharmacokinetics

    William J. Jusko

Frequent Co-Authors

Stanley J. Szefler
Stanley J. Szefler University of Colorado Denver
Jerome J. Schentag
Jerome J. Schentag University at Buffalo, State University of New York
Gerhard Levy
Gerhard Levy University at Buffalo, State University of New York
Eric P. Hoffman
Eric P. Hoffman Binghamton University
Giovanni A. Fava
Giovanni A. Fava University at Buffalo, State University of New York
David M. Janicke
David M. Janicke University of Florida
Sheldon L. Spector
Sheldon L. Spector University of California, Los Angeles
Brian T. Tsuji
Brian T. Tsuji University at Buffalo, State University of New York
Elizabeth A. Repasky
Elizabeth A. Repasky Roswell Park Cancer Institute
Frank Z. Stanczyk
Frank Z. Stanczyk University of Southern California

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