Jürgen B. Bulitta

Best Publications

• Resurgence of colistin: a review of resistance, toxicity, pharmacodynamics, and dosing.

  Lauren M Lim;Neang S Ly;Dana Anderson;Jenny C Yang

  548
  Citations

• Pharmacokinetic/Pharmacodynamic Investigation of Colistin against Pseudomonas aeruginosa Using an In Vitro Model

  Phillip John Bergen;Jurgen B Bulitta;Alan Forrest;Brian Tsuji

  218
  Citations

• Combination therapy for carbapenem-resistant Gram-negative bacteria

  Unknown

  192
  Citations

• Population pharmacokinetics and pharmacodynamics of continuous versus short-term infusion of imipenem-cilastatin in critically ill patients in a randomized, controlled trial

  Unknown

  189
  Citations

• Generating Robust and Informative Nonclinical In Vitro and In Vivo Bacterial Infection Model Efficacy Data To Support Translation to Humans.

  Jürgen B. Bulitta;William W. Hope;Ann E. Eakin;Tina Guina

  165
  Citations

• Synergistic Killing of Multidrug-Resistant Pseudomonas aeruginosa at Multiple Inocula by Colistin Combined with Doripenem in an In Vitro Pharmacokinetic/Pharmacodynamic Model

  Phillip J. Bergen;Brian T. Tsuji;Jurgen B. Bulitta;Alan Forrest

  149
  Citations

• Attenuation of Colistin Bactericidal Activity by High Inoculum of Pseudomonas aeruginosa Characterized by a New Mechanism-Based Population Pharmacodynamic Model

  Jurgen Bernd Bulitta;Jenny C Yang;Liliana Yohonn;Liliana Yohonn;Neang S Ly

  146
  Citations

• Ertapenem Pharmacokinetics and Impact on Intestinal Microflora, in Comparison to Those of Ceftriaxone, after Multiple Dosing in Male and Female Volunteers

  Mathias W. R. Pletz;Mareike Rau;Juergen Bulitta;Andres De Roux

  146
  Citations

• Systematic comparison of the population pharmacokinetics and pharmacodynamics of piperacillin in cystic fibrosis patients and healthy volunteers

  J. B. Bulitta;S. B. Duffull;M. Kinzig-Schippers;U. Holzgrabe

  135
  Citations

• The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections

  T. Tängdén;V. Ramos Martín;T. W. Felton;E. I. Nielsen

  133
  Citations

• Clinical population pharmacokinetics and toxicodynamics of linezolid

  Lauren Marie Boak;Craig Robert Rayner;M Lindsay Grayson;M Lindsay Grayson;David L Paterson

  132
  Citations

• Evaluation by Monte Carlo Simulation of the Pharmacokinetics of Two Doses of Meropenem Administered Intermittently or as a Continuous Infusion in Healthy Volunteers

  Wolfgang A. Krueger;Jurgen Bulitta;Martina Kinzig-Schippers;Cornelia Landersdorfer

  124
  Citations

• Pharmacokinetic-pharmacodynamic rationale for cefepime dosing regimens in intensive care units

  Juliana F. Roos;Jurgen Bulitta;Jeffrey Lipman;Carl M. J. Kirkpatrick

  122
  Citations

• Clinically Relevant Plasma Concentrations of Colistin in Combination with Imipenem Enhance Pharmacodynamic Activity against Multidrug-Resistant Pseudomonas aeruginosa at Multiple Inocula

  Phillip J. Bergen;Alan Forrest;Jürgen B. Bulitta;Brian T. Tsuji

  116
  Citations

• Synergistic Activity of Colistin and Rifampin Combination against Multidrug-Resistant Acinetobacter baumannii in an In Vitro Pharmacokinetic/Pharmacodynamic Model

  Hee Ji Lee;Phillip John Bergen;Jurgen Bernd Bulitta;Jurgen Bernd Bulitta;Brian Tsuji

  114
  Citations

• Development and qualification of a pharmacodynamic model for the pronounced inoculum effect of ceftazidime against Pseudomonas aeruginosa.

  Jiirgen B. Bulitta;Neang S. Ly;Jenny C. Yang;Alan Forrest

  114
  Citations

• Phase 2, Randomized, Double-Blind, Dose-Ranging Study Evaluating the Safety, Tolerability, Population Pharmacokinetics, and Efficacy of Oral Torezolid Phosphate in Patients with Complicated Skin and Skin Structure Infections

  Unknown

  111
  Citations

• Two Mechanisms of Killing of Pseudomonas aeruginosa by Tobramycin Assessed at Multiple Inocula via Mechanism-Based Modeling

  Jurgen Bernd Bulitta;Jurgen Bernd Bulitta;Neang S Ly;Cornelia Barbara Landersdorfer;Nicholin Agata Wanigaratne

  100
  Citations

• Colistin and Polymyxin B Dosage Regimens against Acinetobacter baumannii: Differences in Activity and the Emergence of Resistance

  Soon Ee Cheah;Jian Li;Brian T. Tsuji;Alan Forrest

  94
  Citations

• The Combination of Colistin and Doripenem Is Synergistic against Klebsiella pneumoniae at Multiple Inocula and Suppresses Colistin Resistance in an In Vitro Pharmacokinetic/Pharmacodynamic Model

  Zakuan Z. Deris;Heidi H. Yu;Kathryn Davis;Rachel L. Soon;Rachel L. Soon

  90
  Citations