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Biology and Biochemistry

D-Index
60
Citations
18571
World Ranking
11744
National Ranking
5053

Overview

Marguerite R. Irvin is affiliated with the University of Alabama at Birmingham in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a strong focus on Genetics, Molecular Biology, Cardiology and Cardiovascular Medicine, Endocrinology, Diabetes and Metabolism, and Physiology.

Irvin's work addresses a variety of main topics including Genetic Associations and Epidemiology, Epigenetics and DNA Methylation, Metabolomics and Mass Spectrometry Studies, Genomics and Rare Diseases, Birth, Development, and Health, Renal Diseases and Glomerulopathies, and Nutritional Studies and Diet.

They have published extensively in a number of scientific venues. Frequent publication outlets include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Nature Communications
  • Nature
  • Journal of the American College of Cardiology

Among the recent papers by Marguerite R. Irvin are:

  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program, 2021, Nature
  • Inherited causes of clonal haematopoiesis in 97,691 whole genomes, 2020, Nature
  • Genetic diversity fuels gene discovery for tobacco and alcohol use, 2022, Nature
  • Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale, 2020, Nature Genetics
  • Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations, 2022, Genome Medicine

Irvin has collaborated frequently with a number of researchers, reflecting interdisciplinary and multi-institutional research efforts. Notable co-authors include:

  • Donna K. Arnett
  • Hemant K. Tiwari
  • Xiuqing Guo
  • Myriam Fornage
  • Stephen S. Rich

Best Publications

  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.

    Daniel Taliun;Daniel N. Harris;Michael D. Kessler;Jedidiah Carlson;Jedidiah Carlson

  • Epigenetic Signatures of Cigarette Smoking

    Roby Joehanes;Allan C. Just;Riccardo E. Marioni;Luke C. Pilling

  • Inherited causes of clonal haematopoiesis in 97,691 whole genomes.

    Alexander G Bick;Joshua S Weinstock;Satish K Nandakumar;Satish K Nandakumar;Charles P Fulco;Charles P Fulco

  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

    Daniel Taliun;Daniel N. Harris;Michael D. Kessler;Jedidiah Carlson;Jedidiah Carlson

  • A DNA methylation biomarker of alcohol consumption.

    C Liu;R E Marioni;R E Marioni;Åsa K Hedman;L Pfeiffer

  • Epigenome-wide Association Study (EWAS) of BMI, BMI Change, and Waist Circumference in African American Adults Identifies Multiple Replicated Loci

    Ellen W. Demerath;Weihua Guan;Megan L. Grove;Stella Aslibekyan

  • Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

    Madeline H Kowalski;Huijun Qian;Ziyi Hou;Jonathan D Rosen

  • A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.

    Keri L. Monda;Keri L. Monda;Gary K. Chen;Kira C. Taylor;Kira C. Taylor;Cameron Palmer;Cameron Palmer

  • Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

    Rainer Malik;Ganesh Chauhan;Matthew Traylor;Muralidharan Sargurupremraj

  • Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach

    Michael M Mendelson;Michael M Mendelson;Michael M Mendelson;Riccardo E. Marioni;Riccardo E. Marioni;Roby Joehanes;Roby Joehanes;Chunyu Liu;Chunyu Liu

  • Systematic Error Removal Using Random Forest for Normalizing Large-Scale Untargeted Lipidomics Data.

    Sili Fan;Tobias Kind;Tomas Cajka;Stanley L. Hazen

  • Loci associated with ischaemic stroke and its subtypes (SiGN) : A genome-wide association study

    Sara L Pulit;Patrick F McArdle;Quenna Wong;Rainer Malik

  • Epigenome-Wide Association Study of Fasting Blood Lipids in the Genetics of Lipid Lowering Drugs and Diet Network Study

    Marguerite R. Irvin;Degui Zhi;Roby Joehanes;Michael Mendelson

  • Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale

    Xihao Li;Zilin Li;Hufeng Zhou;Sheila M Gaynor

  • Prevalence of apparent treatment-resistant hypertension among individuals with CKD.

    Rikki M. Tanner;David A. Calhoun;Emmy K. Bell;C. Barrett Bowling;C. Barrett Bowling

  • DNA methylation analysis identifies loci for blood pressure regulation

    Melissa A. Richard;Tianxiao Huan;Symen Ligthart;Rahul Gondalia

  • Epigenome‐wide study identifies novel methylation loci associated with body mass index and waist circumference

    Stella Aslibekyan;Ellen W. Demerath;Michael Mendelson;Degui Zhi

  • Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging.

    Daniel L McCartney;Josine L Min;Rebecca C Richmond;Ake T Lu

  • Epigenome-wide association study of fasting measures of glucose, insulin, and HOMA-IR in the Genetics of Lipid Lowering Drugs and Diet Network study.

    Bertha Hidalgo;M. Ryan Irvin;Jin Sha;Degui Zhi

  • SNPs located at CpG sites modulate genome-epigenome interaction

    Degui Zhi;Stella Aslibekyan;Marguerite R Irvin;Steven A Claas

Frequent Co-Authors

Donna K. Arnett
Donna K. Arnett University of South Carolina
Eric Boerwinkle
Eric Boerwinkle The University of Texas Health Science Center at Houston
Bruce M. Psaty
Bruce M. Psaty University of Washington
Alexander P. Reiner
Alexander P. Reiner University of Washington
Jerome I. Rotter
Jerome I. Rotter UCLA Medical Center
Myriam Fornage
Myriam Fornage The University of Texas Health Science Center at Houston
Jose M. Ordovas
Jose M. Ordovas Tufts University
Leslie A. Lange
Leslie A. Lange University of Colorado Anschutz Medical Campus
Sharon L.R. Kardia
Sharon L.R. Kardia University of Michigan–Ann Arbor
Xiuqing Guo
Xiuqing Guo Lundquist Institute

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