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Lukas C. Kapitein

Lukas C. Kapitein

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
13370
World Ranking
11920
National Ranking
310

Overview

Lukas C. Kapitein is affiliated with Utrecht University in the Netherlands and has a research focus within the fields of Biochemistry, Genetics and Molecular Biology. Their work spans several subfields such as Cell Biology, Molecular Biology, Biophysics, Cellular and Molecular Neuroscience, and Structural Biology.

Their research addresses key topics including:

  • Microtubule and mitosis dynamics
  • Advanced Fluorescence Microscopy Techniques
  • Cellular transport and secretion
  • Cellular Mechanics and Interactions
  • Advanced Electron Microscopy Techniques and Applications
  • Photosynthetic Processes and Mechanisms
  • Photoreceptor and optogenetics research

Kapitein's recent publications illustrate contributions across high-impact life sciences journals. Notable papers include:

  • "Mechanisms of microtubule organization in differentiated animal cells" (2022) published in Nature Reviews Molecular Cell Biology
  • "Direct observation of motor protein stepping in living cells using MINFLUX" (2023) published in Science
  • "The structure and global distribution of the endoplasmic reticulum network are actively regulated by lysosomes" (2020) published in Science Advances
  • "Concerted action of kinesins KIF5B and KIF13B promotes efficient secretory vesicle transport to microtubule plus ends" (2020) published in eLife
  • "Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the microtubule cytoskeleton" (2020) published in Nature Communications

They have frequently collaborated with several co-authors, including:

  • Anna Akhmanova
  • Wilco Nijenhuis
  • Eugene A. Katrukha
  • Malina K. Iwanski
  • Daphne Jurriens

Their work is regularly published in venues such as bioRxiv (Cold Spring Harbor Laboratory), eLife, Angewandte Chemie International Edition, The Journal of Cell Biology, and Angewandte Chemie. The most frequent publication outlet has been bioRxiv, with 31 publications.

Best Publications

  • The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks

    Lukas C. Kapitein;Erwin J. G. Peterman;Benjamin H. Kwok;Jeffrey H. Kim

  • Dynamic Microtubules Regulate Dendritic Spine Morphology and Synaptic Plasticity

    Jacek Jaworski;Lukas C. Kapitein;Susana Montenegro Gouveia;Bjorn R. Dortland

  • Microtubule Stabilization Reduces Scarring and Causes Axon Regeneration After Spinal Cord Injury

    Farida Hellal;Andres Hurtado;Jörg Ruschel;Kevin C. Flynn

  • Building the Neuronal Microtubule Cytoskeleton

    Lukas C. Kapitein;Casper C. Hoogenraad

  • TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites.

    Myrrhe van Spronsen;Myrrhe van Spronsen;Marina Mikhaylova;Marina Mikhaylova;Joanna Lipka;Joanna Lipka;Max A. Schlager

  • Mixed Microtubules Steer Dynein-Driven Cargo Transport into Dendrites

    Lukas C. Kapitein;Max A. Schlager;Marijn Kuijpers;Phebe S. Wulf

  • Optogenetic control of organelle transport and positioning

    Petra van Bergeijk;Max Adrian;Casper C. Hoogenraad;Lukas C. Kapitein

  • Axon extension occurs independently of centrosomal microtubule nucleation.

    Michael Stiess;Nicola Maghelli;Lukas C. Kapitein;Susana Gomis-Rüth

  • Which way to go? Cytoskeletal organization and polarized transport in neurons.

    Lukas C. Kapitein;Casper C. Hoogenraad

  • Differentiation between Oppositely Oriented Microtubules Controls Polarized Neuronal Transport

    Roderick P. Tas;Anaël Chazeau;Bas M.C. Cloin;Maaike L.A. Lambers

  • Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development.

    Kah Wai Yau;Kah Wai Yau;Sam F.B. van Beuningen;Inês Cunha-Ferreira;Bas M.C. Cloin

  • Microtubule‐binding protein doublecortin‐like kinase 1 (DCLK1) guides kinesin‐3‐mediated cargo transport to dendrites

    Joanna Lipka;Joanna Lipka;Lukas C Kapitein;Jacek Jaworski;Casper C Hoogenraad

  • TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays.

    Sam F.B. van Beuningen;Lena Will;Martin Harterink;Anaël Chazeau

  • Dendrites In Vitro and In Vivo Contain Microtubules of Opposite Polarity and Axon Formation Correlates with Uniform Plus-End-Out Microtubule Orientation.

    Kah Wai Yau;Philipp Schätzle;Elena Tortosa;Stéphane Pagès

  • Resolving bundled microtubules using anti-tubulin nanobodies

    Marina Mikhaylova;Bas M C Cloin;Kieran Finan;Robert van den Berg

  • MAP2 Defines a Pre-axonal Filtering Zone to Regulate KIF1- versus KIF5-Dependent Cargo Transport in Sensory Neurons

    Laura F. Gumy;Eugene A. Katrukha;Ilya Grigoriev;Dick Jaarsma

  • Probing Intracellular Motor Protein Activity Using an Inducible Cargo Trafficking Assay

    Lukas C. Kapitein;Max A. Schlager;Wouter A. van der Zwan;Phebe S. Wulf

  • Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis.

    Max A Schlager;Lukas C Kapitein;Ilya Grigoriev;Grzegorz M Burzynski

  • EGFR Dynamics Change during Activation in Native Membranes as Revealed by NMR

    Mohammed Kaplan;Siddarth Narasimhan;Cecilia de Heus;Deni Mance

  • Microtubule cross-linking triggers the directional motility of kinesin-5

    Lukas C. Kapitein;Benjamin H. Kwok;Joshua S. Weinger;Christoph F. Schmidt;Christoph F. Schmidt

Frequent Co-Authors

Casper C. Hoogenraad
Casper C. Hoogenraad Utrecht University
Anna Akhmanova
Anna Akhmanova Utrecht University
Michel O. Steinmetz
Michel O. Steinmetz Paul Scherrer Institute
Erik Meijering
Erik Meijering University of New South Wales
R. Jeroen Pasterkamp
R. Jeroen Pasterkamp Utrecht University
Tarun M. Kapoor
Tarun M. Kapoor Rockefeller University
Dick Jaarsma
Dick Jaarsma Erasmus University Rotterdam
Maarten H.P. Kole
Maarten H.P. Kole Utrecht University
Judith Klumperman
Judith Klumperman Utrecht University

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