D-Index & Metrics Best Publications
Paul M. P. van Bergen en Henegouwen

Paul M. P. van Bergen en Henegouwen

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 45 Citations 7,236 95 World Ranking 12850 National Ranking 287

Overview

What is he best known for?

The fields of study he is best known for:

  • Cancer
  • Cell membrane
  • Antibody

His primary areas of study are Cell biology, Antibody, Molecular biology, Epidermal growth factor receptor and Monoclonal antibody. The study incorporates disciplines such as Epidermal growth factor and Clathrin in addition to Cell biology. His research in Molecular biology intersects with topics in Transcytosis, Caveolae, Receptor-mediated endocytosis and Actin cytoskeleton.

Epidermal growth factor receptor is a subfield of Receptor that Paul M.P. van Bergen en Henegouwen studies. His Monoclonal antibody research includes themes of Molecular imaging, Cancer research and Immunogenicity. His work in Signal transduction tackles topics such as Kinase which are related to areas like Tyrosine kinase.

His most cited work include:

  • A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K–Akt signalling (300 citations)
  • Efficient inhibition of EGFR signaling and of tumour growth by antagonistic anti-EFGR Nanobodies. (285 citations)
  • The epidermal growth factor. (266 citations)

What are the main themes of his work throughout his whole career to date?

Paul M.P. van Bergen en Henegouwen mostly deals with Cell biology, Molecular biology, Cancer research, Epidermal growth factor receptor and Biophysics. His Cell biology research incorporates themes from Epidermal growth factor, Endocytosis and Cytoskeleton. His Molecular biology study also includes fields such as

  • Antibody together with Immunotherapy,
  • T cell, which have a strong connection to Cancer cell.

The concepts of his Cancer research study are interwoven with issues in Cancer, Photosensitizer, Photodynamic therapy, Monoclonal antibody and In vivo. His Epidermal growth factor receptor study deals with the bigger picture of Receptor. His Biophysics research integrates issues from Quantum dot, Microscopy and Fluorescence, Förster resonance energy transfer.

He most often published in these fields:

  • Cell biology (36.00%)
  • Molecular biology (24.00%)
  • Cancer research (20.00%)

What were the highlights of his more recent work (between 2016-2021)?

  • Cancer research (20.00%)
  • Biophysics (16.00%)
  • T cell (4.80%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Cancer research, Biophysics, T cell, In vitro and Signal transduction. His study on Cancer research also encompasses disciplines like

  • Endothelial stem cell, Cytotoxicity, Combination therapy and Epidermal growth factor receptor most often made with reference to Photosensitizer,
  • Cancer cell which connect with Antibody,
  • Biodistribution which intersects with area such as Intravital microscopy, Necrosis, Colocalization and Tumor necrosis factor alpha. The various areas that Paul M.P. van Bergen en Henegouwen examines in his Biophysics study include Membrane, Transmembrane domain, Molecule and Crystal structure.

Paul M.P. van Bergen en Henegouwen combines subjects such as Molecular biology and Antigen with his study of T cell. His study with Signal transduction involves better knowledge in Cell biology. His studies deal with areas such as Allosteric regulation and Cell growth as well as Cell biology.

Between 2016 and 2021, his most popular works were:

  • Antibody or Antibody Fragments : Implications for Molecular Imaging and Targeted Therapy of Solid Tumors (68 citations)
  • Probing cytoskeletal modulation of passive and active intracellular dynamics using nanobody-functionalized quantum dots (47 citations)
  • ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy. (34 citations)

In his most recent research, the most cited papers focused on:

  • Cancer
  • Cell membrane
  • Biochemistry

Paul M.P. van Bergen en Henegouwen spends much of his time researching Cancer research, T cell, Cancer immunotherapy, Biophysics and Photosensitizer. His Cancer research research is multidisciplinary, incorporating perspectives in Necrosis, Intravital microscopy and Colocalization. Paul M.P. van Bergen en Henegouwen interconnects Tyrosine kinase, Dimer and Phosphorylation in the investigation of issues within Biophysics.

His research investigates the connection between Photosensitizer and topics such as Photodynamic therapy that intersect with problems in Breast cancer, In vivo, Tumor necrosis factor alpha and Biodistribution. In Cancer cell, Paul M.P. van Bergen en Henegouwen works on issues like T-cell receptor, which are connected to Antibody. His research integrates issues of Molecular biology, CD3 and Antigen in his study of Antibody.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Efficient inhibition of EGFR signaling and of tumour growth by antagonistic anti-EFGR Nanobodies.

Rob C. Roovers;Toon Laeremans;Lieven Huang;Severine De Taeye.
Cancer Immunology, Immunotherapy (2007)

433 Citations

The epidermal growth factor.

Johannes Boonstra;Philip Rijken;Bruno Humbel;Fons Cremers.
Cell Biology International (1995)

406 Citations

A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K–Akt signalling

Lara Fallon;Catherine M.L. Bélanger;Amadou T. Corera;Maria Kontogiannea.
Nature Cell Biology (2006)

400 Citations

Amphiregulin Enhances Regulatory T Cell-Suppressive Function via the Epidermal Growth Factor Receptor

Dietmar M.W. Zaiss;Jorg van Loosdregt;Andrea Gorlani;Cornelis P.J. Bekker.
Immunity (2013)

267 Citations

ErbB1 dimerization is promoted by domain co-confinement and stabilized by ligand binding

Shalini T Low-Nam;Keith A Lidke;Patrick J Cutler;Rob C Roovers.
Nature Structural & Molecular Biology (2011)

235 Citations

A biparatopic anti-EGFR nanobody efficiently inhibits solid tumour growth

Rob C. Roovers;Maria J.W.D. Vosjan;Toon Laeremans;Rachid el Khoulati.
International Journal of Cancer (2011)

212 Citations

The blood-brain barrier transmigrating single domain antibody: mechanisms of transport and antigenic epitopes in human brain endothelial cells.

Abedelnasser Abulrob;Hein Sprong;Paul Van Bergen en Henegouwen;Danica Stanimirovic.
Journal of Neurochemistry (2005)

212 Citations

Integrated fluorescence and transmission electron microscopy.

Alexandra V. Agronskaia;Jack A. Valentijn;Linda F. van Driel;Chris T.W.M. Schneijdenberg.
Journal of Structural Biology (2008)

200 Citations

Nanobody-based cancer therapy of solid tumors

Marta Kijanka;Bram Dorresteijn;Sabrina Oliveira;Paul M P van Bergen en Henegouwen.
Nanomedicine: Nanotechnology, Biology and Medicine (2015)

192 Citations

Association and Colocalization of Eps15 with Adaptor Protein-2 and Clathrin

Sanne van Delft;Christopher Schumacher;Willem Hage;Arie J. Verkleij.
Journal of Cell Biology (1997)

185 Citations

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