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Henk M.W. Verheul

Henk M.W. Verheul

D-Index & Metrics

Biology and Biochemistry

D-Index
76
Citations
19860
World Ranking
5069
National Ranking
124

Overview

Henk M.W. Verheul is affiliated with Radboud University in the Netherlands. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on Oncology and Cancer Research. Subfields in which they have contributed substantially include Pulmonary and Respiratory Medicine, Surgery, and Molecular Biology.

Their work covers several main topics related to cancer study and treatment, including Cancer Genomics and Diagnostics, Colorectal Cancer Treatments and Studies, and Cancer Immunotherapy and Biomarkers. Other topics include Lung Cancer Treatments and Mutations, Colorectal Cancer Surgical Treatments, Gastric Cancer Management and Outcomes, and Pancreatic and Hepatic Oncology Research.

Frequent publication venues for their research consist of notable journals such as:

  • Journal of Clinical Oncology
  • Annals of Oncology
  • Clinical Cancer Research
  • Cancers
  • European Journal of Cancer

Among their recent papers are:

  • Ten-Year Outcome of Neoadjuvant Chemoradiotherapy Plus Surgery for Esophageal Cancer: The Randomized Controlled CROSS Trial, 2021, Journal of Clinical Oncology
  • γδ T cells are effectors of immunotherapy in cancers with HLA class I defects, 2023, Nature
  • White blood cell and cell-free DNA analyses for detection of residual disease in gastric cancer, 2020, Nature Communications
  • A first-in-man phase 1 study of the DNA-dependent protein kinase inhibitor peposertib (formerly M3814) in patients with advanced solid tumours, 2020, British Journal of Cancer
  • Detection and localization of early- and late-stage cancers using platelet RNA, 2022, Cancer Cell

Henk M.W. Verheul has collaborated frequently with several researchers including:

  • Hans Gelderblom
  • Emile E. Voest
  • Laurien J. Zeverijn
  • Mariëtte Labots
  • Paul Roepman

Best Publications

  • RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics

    Myron G. Best;Nik Sol;Irsan Kooi;Jihane Tannous

  • Anti-angiogenic tyrosine kinase inhibitors: what is their mechanism of action?

    Kristy J. Gotink;Henk M. W. Verheul

  • MicroRNA-21 in Pancreatic Cancer: Correlation with Clinical Outcome and Pharmacologic Aspects Underlying Its Role in the Modulation of Gemcitabine Activity

    Elisa Giovannetti;Niccola Funel;Godefridus J. Peters;Marco Del Chiaro

  • Involvement of platelets in tumour angiogenesis

    H. M. Pinedo;H. M. W. Verheul;R. J. D'amato;R. J. D'amato;J. Folkman;J. Folkman

  • Chemotherapy versus chemoradiotherapy after surgery and preoperative chemotherapy for resectable gastric cancer (CRITICS): an international, open-label, randomised phase 3 trial

    Annemieke Cats;Edwin P M Jansen;Nicole C T van Grieken;Karolina Sikorska

  • Ten-Year Outcome of Neoadjuvant Chemoradiotherapy Plus Surgery for Esophageal Cancer: The Randomized Controlled CROSS Trial

    Ben M Eyck;J Jan B van Lanschot;J Jan B van Lanschot;Maarten C C M Hulshof;Berend J van der Wilk

  • Blood platelets contain tumor-derived RNA biomarkers

    R. Jonas A. Nilsson;R. Jonas A. Nilsson;Leonora Balaj;Leonora Balaj;Esther Hulleman;Sjoerd van Rijn

  • Class II Histone Deacetylases Are Associated with VHL-Independent Regulation of Hypoxia-Inducible Factor 1α

    David Z. Qian;Sushant K. Kachhap;Spencer J. Collis;Henk M.W. Verheul

  • Rapid Decrease in Delivery of Chemotherapy to Tumors after Anti-VEGF Therapy: Implications for Scheduling of Anti-Angiogenic Drugs

    Astrid A.M. Van der Veldt;Mark Lubberink;Mark Lubberink;Idris Bahce;Maudy Walraven

  • Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance

    Kristy J. Gotink;Henk J. Broxterman;Mariette Labots;Richard R. de Haas

  • Loss of Muscle Mass During Chemotherapy Is Predictive for Poor Survival of Patients With Metastatic Colorectal Cancer

    Susanne Blauwhoff-Buskermolen;Kathelijn S. Versteeg;Marian A.E. de van der Schueren;Nicole R. den Braver

  • Targeting tumor angiogenesis with histone deacetylase inhibitors : the hydroxamic acid derivative LBH589

    David Z. Qian;Yukihiko Kato;Shabana Shabbeer;Yongfeng Wei

  • Understanding the causes of multidrug resistance in cancer: a comparison of doxorubicin and sunitinib.

    Henk J. Broxterman;Kristy J. Gotink;Henk M.W. Verheul

  • The first-in-human study of the hydrogen sulfate (Hyd-sulfate) capsule of the MEK1/2 inhibitor AZD6244 (ARRY-142886): a phase I open-label multicenter trial in patients with advanced cancer.

    Udai Banerji;D. Ross Camidge;Henk M. W. Verheul;Roshan Agarwal

  • Signalling pathways in vasculogenic mimicry.

    Yvette W.J. Paulis;Patricia M.M.B. Soetekouw;Henk M.W. Verheul;Vivianne C.G. Tjan-Heijnen

  • The Rise of Allogeneic Natural Killer Cells As a Platform for Cancer Immunotherapy: Recent Innovations and Future Developments.

    John P. Veluchamy;Nina Kok;Hans J. van der Vliet;Henk M. W. Verheul

  • The Drug Rediscovery protocol facilitates the expanded use of existing anticancer drugs

    D. L. van der Velden;L. R. Hoes;H. van der Wijngaart;J. M. van Berge Henegouwen

  • Reversible Epithelial to Mesenchymal Transition and Acquired Resistance to Sunitinib in Patients with Renal Cell Carcinoma: Evidence from a Xenograft Study

    Hans J. Hammers;Henk M. Verheul;Henk M. Verheul;Brenda Salumbides;Rajni Sharma

  • White blood cell and cell-free DNA analyses for detection of residual disease in gastric cancer

    Alessandro Leal;Nicole C. T. Van Grieken;Doreen N. Palsgrove;Jillian Phallen

  • Treatment outcome of patients with recurrent glioblastoma multiforme: a retrospective multicenter analysis

    Myra E. van Linde;Cyrillo G. Brahm;Philip C. de Witt Hamer;Jaap C. Reijneveld

Frequent Co-Authors

Connie R. Jimenez
Connie R. Jimenez Vrije Universiteit Amsterdam
Tanja D. de Gruijl
Tanja D. de Gruijl Vrije Universiteit Amsterdam
Sander R. Piersma
Sander R. Piersma VU University Medical Center
Henk L. Dekker
Henk L. Dekker University of Amsterdam
Arjan W. Griffioen
Arjan W. Griffioen University of Amsterdam
Godefridus J. Peters
Godefridus J. Peters Gdańsk Medical University
Otto S. Hoekstra
Otto S. Hoekstra Amsterdam UMC
Emile E. Voest
Emile E. Voest Antoni van Leeuwenhoek Hospital
Joost Dekker
Joost Dekker University of Amsterdam
Bauke Ylstra
Bauke Ylstra Vrije Universiteit Amsterdam

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