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Medicine

D-Index
115
Citations
58941
World Ranking
4481
National Ranking
168

Overview

Egbert F. Smit is affiliated with VU University Medical Center in the Netherlands and has a research focus primarily within the field of Medicine, with notable expertise in pulmonary and respiratory medicine, oncology, and cancer research.

Their work covers key areas such as lung cancer treatments and mutations, lung cancer diagnosis and treatment, colorectal cancer studies, cancer immunotherapy and biomarkers, as well as molecular biology and cancer genomics.

Frequent publication venues for Smit include the following:

  • Annals of Oncology
  • Journal of Clinical Oncology
  • Journal of Thoracic Oncology
  • Lung Cancer
  • Cancer Research

Collaborations are an important aspect of their research, with frequent coauthors being:

  • Enriqueta Felip
  • Anne-Marie C. Dingemans
  • Kim Monkhorst
  • Adrianus J. de Langen
  • Vincent van der Noort

Recent publications illustrate a focus on oncogene-addicted and non-oncogene-addicted metastatic non-small-cell lung cancer, as well as targeted treatments and mutations. Notable papers include:

  • "Capmatinib in MET Exon 14-Mutated or MET -Amplified Non-Small-Cell Lung Cancer," 2020, New England Journal of Medicine
  • "Trastuzumab Deruxtecan in HER2 -Mutant Non-Small-Cell Lung Cancer," 2021, New England Journal of Medicine
  • "Tepotinib in Non-Small-Cell Lung Cancer with MET Exon 14 Skipping Mutations," 2020, New England Journal of Medicine
  • "Oncogene-addicted metastatic non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up," 2023, Annals of Oncology
  • "Non-oncogene-addicted metastatic non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up," 2023, Annals of Oncology

Their publications have garnered significant citations, with some papers cited over 900 times, reflecting the relevance of their research within the field.

Best Publications

  • Multi-Institutional Randomized Phase II Trial of Gefitinib for Previously Treated Patients With Advanced Non–Small-Cell Lung Cancer

    Masahiro Fukuoka;Seiji Yano;Giuseppe Giaccone;Tomohide Tamura

  • Durvalumab plus platinum–etoposide versus platinum–etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trial

    Luis Paz-Ares;Mikhail Dvorkin;Yuanbin Chen;Niels Reinmuth

  • Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

    Martin Peifer;Lynnette Fernández-Cuesta;Martin L. Sos;Julie George

  • Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two randomised trials

    Joe Y Chang;Suresh Senan;Marinus A. Paul;Reza John Mehran

  • Dabrafenib plus trametinib in patients with previously untreated BRAFV600E-mutant metastatic non-small-cell lung cancer: an open-label, phase 2 trial

    David Planchard;Egbert F Smit;Harry J M Groen;Julien Mazieres

  • Effectiveness of positron emission tomography in the preoperative assessment of patients with suspected non-small-cell lung cancer: the PLUS multicentre randomised trial.

    Harm Van Tinteren;Otto S. Hoekstra;Egbert F. Smit;Jan H.A.M. Van Den Bergh

  • Long-term expanding human airway organoids for disease modeling

    Norman Sachs;Angelos Papaspyropoulos;Domenique D. Zomer-van Ommen;Inha Heo

  • Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer

    Jonathan Weiss;Martin L. Sos;Danila Seidel;Martin Peifer

  • Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids

    Krijn K Dijkstra;Chiara M Cattaneo;Fleur Weeber;Myriam Chalabi

  • Pan-cancer whole-genome analyses of metastatic solid tumours

    Peter Priestley;Jonathan Baber;Martijn P. Lolkema;Neeltje Steeghs

  • RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics

    Myron G. Best;Nik Sol;Irsan Kooi;Jihane Tannous

  • Randomized Controlled Trial of Resection Versus Radiotherapy After Induction Chemotherapy in Stage IIIA-N2 Non–Small-Cell Lung Cancer

    Jan P. van Meerbeeck;Gijs W. P. M. Kramer;Paul E. Y. Van Schil;Catherine Legrand

  • A genomics-based classification of human lung tumors

    Danila Seidel;Thomas Zander;Lukas C. Heukamp;Martin Peifer

  • Tepotinib in Non–Small-Cell Lung Cancer with MET Exon 14 Skipping Mutations

    Paul K. Paik;Enriqueta Felip;Remi Veillon;Hiroshi Sakai

  • Trastuzumab Deruxtecan in HER2-Mutant Non-Small-Cell Lung Cancer.

    Bob T Li;Egbert F Smit;Yasushi Goto;Kazuhiko Nakagawa

  • Outcomes of Risk-Adapted Fractionated Stereotactic Radiotherapy for Stage I Non-Small-Cell Lung Cancer

    Frank J. Lagerwaard;Cornelis J.A. Haasbeek;Egbert F. Smit;Ben J. Slotman

  • Brigatinib in Patients With Crizotinib-Refractory Anaplastic Lymphoma Kinase–Positive Non–Small-Cell Lung Cancer: A Randomized, Multicenter Phase II Trial

    Dong-Wan Kim;Dong-Wan Kim;Marcello Tiseo;Myung-Ju Ahn;Karen L Reckamp

  • 2nd ESMO Consensus Conference on Lung Cancer: early-stage non-small-cell lung cancer consensus on diagnosis, treatment and follow-up

    J. Vansteenkiste;L. Crinò;C. Dooms;J. Y. Douillard

  • Durvalumab, with or without tremelimumab, plus platinum-etoposide versus platinum-etoposide alone in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): updated results from a randomised, controlled, open-label, phase 3 trial.

    Jonathan W Goldman;Mikhail Dvorkin;Yuanbin Chen;Niels Reinmuth

  • Three-Arm Randomized Study of Two Cisplatin-Based Regimens and Paclitaxel Plus Gemcitabine in Advanced Non–Small-Cell Lung Cancer: A Phase III Trial of the European Organization for Research and Treatment of Cancer Lung Cancer Group—EORTC 08975

    Egbert F. Smit;Jan P.A.M. van Meerbeeck;Pilar Lianes;Channa Debruyne

Frequent Co-Authors

Pieter E. Postmus
Pieter E. Postmus Leiden University Medical Center
Harry J.M. Groen
Harry J.M. Groen University Medical Center Groningen
Suresh Senan
Suresh Senan University of Amsterdam
Otto S. Hoekstra
Otto S. Hoekstra Amsterdam UMC
Anne-Marie C. Dingemans
Anne-Marie C. Dingemans Erasmus University Rotterdam
Ronald Boellaard
Ronald Boellaard Amsterdam UMC
Adriaan A. Lammertsma
Adriaan A. Lammertsma VU University Medical Center
Peter J.F. Snijders
Peter J.F. Snijders Vrije Universiteit Amsterdam
Giuseppe Giaccone
Giuseppe Giaccone Cornell University
Luis Paz-Ares
Luis Paz-Ares Complutense University of Madrid

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