World's Best Scientists 2026 revealed!
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Best Female Scientists
2025
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Medicine
Canada
2023

D-Index & Metrics

Best Female Scientists

D-Index
143
Citations
93021
World Ranking
204
National Ranking
5

Medicine

D-Index
146
Citations
97465
World Ranking
1320
National Ranking
42

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2023 - Research.com Medicine in Canada Leader Award
  • 2018 - Canada Gairdner Wightman Award

Overview

Frances A. Shepherd is affiliated with the Princess Margaret Cancer Centre in Canada. Their research primarily focuses on the field of Medicine, with substantial contributions spanning Pulmonary and Respiratory Medicine, Oncology, Cancer Research, Molecular Biology, and Radiology, Nuclear Medicine and Imaging.

The main topics addressed in their research include:

  • Lung Cancer Treatments and Mutations
  • Lung Cancer Research Studies
  • Cancer Genomics and Diagnostics
  • Lung Cancer Diagnosis and Treatment
  • Cancer Immunotherapy and Biomarkers
  • Colorectal Cancer Treatments and Studies
  • Gastric Cancer Management and Outcomes

The scientist has published extensively in several key journals, which include:

  • Journal of Thoracic Oncology
  • Journal of Clinical Oncology
  • Annals of Oncology
  • Lung Cancer
  • Clinical Lung Cancer

Frequent coauthors collaborating with Frances A. Shepherd are:

  • Natasha B. Leighl
  • Geoffrey Liu
  • Adrian G. Sacher
  • Penelope A. Bradbury
  • Ming-Sound Tsao

Among their recent publications are:

  • Osimertinib in Resected EGFR -Mutated Non-Small-Cell Lung Cancer, 2020, New England Journal of Medicine
  • Durvalumab With or Without Tremelimumab vs Standard Chemotherapy in First-line Treatment of Metastatic Non-Small Cell Lung Cancer, 2020, JAMA Oncology
  • Overall Survival with Osimertinib in Resected EGFR -Mutated NSCLC, 2023, New England Journal of Medicine
  • Adjuvant Osimertinib for Resected EGFR-Mutated Stage IB-IIIA Non-Small-Cell Lung Cancer: Updated Results From the Phase III Randomized ADAURA Trial, 2023, Journal of Clinical Oncology
  • Osimertinib versus platinum-pemetrexed for patients with EGFR T790M advanced NSCLC and progression on a prior EGFR-tyrosine kinase inhibitor: AURA3 overall survival analysis, 2020, Annals of Oncology

Frances A. Shepherd has been recognized with the Canada Gairdner Wightman Award in 2018.

Best Publications

  • Erlotinib in previously treated non-small-cell lung cancer.

    Frances A. Shepherd;José Rodrigues Pereira;Tudor Ciuleanu;Eng Huat Tan

  • Randomized Phase III Trial of Pemetrexed Versus Docetaxel in Patients With Non–Small-Cell Lung Cancer Previously Treated With Chemotherapy

    Nasser Hanna;Frances A. Shepherd;Frank V. Fossella;Jose R. Pereira

  • Prospective Randomized Trial of Docetaxel Versus Best Supportive Care in Patients With Non–Small-Cell Lung Cancer Previously Treated With Platinum-Based Chemotherapy

    Frances A. Shepherd;Janet Dancey;Rodryg Ramlau;Karin Mattson

  • Lung Adjuvant Cisplatin Evaluation: A Pooled Analysis by the LACE Collaborative Group

    Jean Pierre Pignon;Hélène Tribodet;Giorgio V. Scagliotti;Jean Yves Douillard

  • Erlotinib in lung cancer - molecular and clinical predictors of outcome.

    Ming Sound Tsao;Akira Sakurada;Jean Claude Cutz;Jean Claude Cutz;Chang Qi Zhu;Chang Qi Zhu

  • Vinorelbine plus Cisplatin vs. Observation in Resected Non–Small-Cell Lung Cancer

    Timothy Winton;Robert Livingston;David H Johnson;James Rigas

  • Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial

    Edward S. Kim;Vera Hirsh;Tony Mok;Mark A. Socinski

  • Radiotherapy plus chemotherapy with or without surgical resection for stage III non-small-cell lung cancer: a phase III randomised controlled trial

    Kathy S Albain;R Suzanne Swann;Valerie W Rusch;Andrew T Turrisi

  • Osimertinib in Resected EGFR-Mutated Non-Small-Cell Lung Cancer.

    Yi-Long Wu;Masahiro Tsuboi;Jie He;Thomas John

  • Characterizing the cancer genome in lung adenocarcinoma

    Barbara A. Weir;Barbara A. Weir;Michele S. Woo;Gad Getz;Sven Perner;Sven Perner

  • Topotecan Versus Cyclophosphamide, Doxorubicin, and Vincristine for the Treatment of Recurrent Small-Cell Lung Cancer

    Joachim von Pawel;Joan H. Schiller;Frances A. Shepherd;Scott Z. Fields

  • Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study.

    Kerby Shedden;Jeremy M.G. Taylor;Steven A. Enkemann;Ming Sound Tsao

  • Nivolumab plus ipilimumab as first-line treatment for advanced non-small-cell lung cancer (CheckMate 012): results of an open-label, phase 1, multicohort study.

    Matthew D. Hellmann;Naiyer A. Rizvi;Jonathan W. Goldman;Scott N. Gettinger

  • The Differential Efficacy of Pemetrexed According to NSCLC Histology: A Review of Two Phase III Studies

    Giorgio Scagliotti;Nasser Hanna;Frank V Fossella;Katherine Sugarman

  • Non-small-cell lung cancer

    Peter Goldstraw;David Ball;James R Jett;Thierry Le Chevalier

  • Role of KRAS and EGFR As Biomarkers of Response to Erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21

    Chang Qi Zhu;Gilda Da Cunha Santos;Keyue Ding;Akira Sakurada

  • EGFR Mutations and Lung Cancer

    Gilda da Cunha Santos;Frances A. Shepherd;Ming Sound Tsao

  • The international association for the study of lung cancer lung cancer staging project: Proposals regarding the clinical staging of small cell lung cancer in the forthcoming (seventh) edition of the tumor, node, metastasis classification for lung cancer

    Frances A. Shepherd;John J. Crowley;Paul Van Houtte;Pieter E. Postmus

  • Lung cancer susceptibility locus at 5p15.33

    James D McKay;Rayjean J Hung;Rayjean J Hung;Valerie Gaborieau;Paolo Boffetta

  • Osimertinib for pretreated EGFR Thr790Met-positive advanced non-small-cell lung cancer (AURA2): a multicentre, open-label, single-arm, phase 2 study

    Glenwood Goss;Chun-Ming Tsai;Frances A Shepherd;Lyudmila Bazhenova

Frequent Co-Authors

Ming-Sound Tsao
Ming-Sound Tsao Princess Margaret Cancer Centre
Natasha B. Leighl
Natasha B. Leighl Princess Margaret Cancer Centre
Geoffrey Liu
Geoffrey Liu Princess Margaret Cancer Centre
Lesley Seymour
Lesley Seymour Queen's University
Melania Pintilie
Melania Pintilie Princess Margaret Cancer Centre
Wei Xu
Wei Xu Shenzhen University
Andrea Bezjak
Andrea Bezjak Princess Margaret Cancer Centre
Suzanne Kamel-Reid
Suzanne Kamel-Reid University Health Network
Igor Jurisica
Igor Jurisica University Health Network
Shaf Keshavjee
Shaf Keshavjee University Health Network

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