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Medicine

D-Index
100
Citations
46652
World Ranking
8169
National Ranking
316

Overview

Harry J.M. Groen is affiliated with the University Medical Center Groningen in the Netherlands. Their research primarily focuses on medicine, with a significant volume of work in pulmonary and respiratory medicine, oncology, cancer research, radiology, nuclear medicine and imaging, and molecular biology.

The scientist's work encompasses a broad range of topics related to lung cancer and cancer biology, including:

  • Lung Cancer Treatments and Mutations
  • Lung Cancer Diagnosis and Treatment
  • Lung Cancer Research Studies
  • Cancer Genomics and Diagnostics
  • Radiomics and Machine Learning in Medical Imaging
  • Cancer Immunotherapy and Biomarkers
  • Colorectal Cancer Treatments and Studies

Several recent publications represent their contributions to the field. Notable papers include:

  • Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial, 2020, New England Journal of Medicine
  • Capmatinib in MET Exon 14-Mutated or MET-Amplified Non-Small-Cell Lung Cancer, 2020, New England Journal of Medicine
  • Phase 2 Study of Dabrafenib Plus Trametinib in Patients With BRAF V600E-Mutant Metastatic NSCLC: Updated 5-Year Survival Rates and Genomic Analysis, 2021, Journal of Thoracic Oncology
  • Efficacy and Safety of Rovalpituzumab Tesirine Compared With Topotecan as Second-Line Therapy in DLL3-High SCLC: Results From the Phase 3 TAHOE Study, 2021, Journal of Thoracic Oncology
  • Immune microenvironment composition in non-small cell lung cancer and its association with survival, 2020, Clinical & Translational Immunology

Frequent collaborators in research include:

  • Ed Schuuring
  • T. Jeroen N. Hiltermann
  • Rozemarijn Vliegenthart
  • Anthonie J. van der Wekken
  • Marjolein A. Heuvelmans

The main publication venues for their research are:

  • Lung Cancer
  • Journal of Thoracic Oncology
  • Cancers
  • Annals of Oncology
  • Journal of Clinical Oncology

This researcher has contributed extensively to literature relating to lung cancer and related oncological fields. Their work spans clinical trials, treatment developments, diagnostic improvements, and molecular insights into cancer biology. The combination of topics, coauthors, and publication venues indicates a consistent focus on advancing understanding and treatment options in pulmonary oncology through interdisciplinary methods.

Best Publications

  • Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial

    Harry J. de Koning;Carlijn M. van der Aalst;Pim A. de Jong;Ernst T. Scholten

  • Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

    Martin Peifer;Lynnette Fernández-Cuesta;Martin L. Sos;Julie George

  • Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two randomised trials

    Joe Y Chang;Suresh Senan;Marinus A. Paul;Reza John Mehran

  • Multiple common variants for celiac disease influencing immune gene expression

    Patrick C. A. Dubois;Gosia Trynka;Lude Franke;Lude Franke;Karen A. Hunt

  • Dabrafenib plus trametinib in patients with previously untreated BRAFV600E-mutant metastatic non-small-cell lung cancer: an open-label, phase 2 trial

    David Planchard;Egbert F Smit;Harry J M Groen;Julien Mazieres

  • Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer

    Jonathan Weiss;Martin L. Sos;Danila Seidel;Martin Peifer

  • Management of lung nodules detected by volume CT scanning

    Rob J van Klaveren;Matthijs Oudkerk;Mathias Prokop;Ernst T Scholten

  • An open-label phase 2 trial of dabrafenib plus trametinib in patients with previously treated BRAF V600E–mutant metastatic non-small cell lung cancer

    David Planchard;Benjamin Besse;Harry J M Groen;Pierre-Jean Souquet

  • A genomics-based classification of human lung tumors

    Danila Seidel;Thomas Zander;Lukas C. Heukamp;Martin Peifer

  • Complication rates of CT-guided transthoracic lung biopsy: meta-analysis

    W. J. Heerink;G. H. de Bock;G. J. de Jonge;H. J. M. Groen

  • Brigatinib in Patients With Crizotinib-Refractory Anaplastic Lymphoma Kinase–Positive Non–Small-Cell Lung Cancer: A Randomized, Multicenter Phase II Trial

    Dong-Wan Kim;Dong-Wan Kim;Marcello Tiseo;Myung-Ju Ahn;Karen L Reckamp

  • Mutations in the DDR2 Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer

    Peter S. Hammerman;Martin L. Sos;Alex H. Ramos;Chunxiao Xu

  • 89Zr-atezolizumab imaging as a non-invasive approach to assess clinical response to PD-L1 blockade in cancer

    Frederike Bensch;Elly L. van der Veen;Marjolijn N. Lub-de Hooge;Annelies Jorritsma-Smit

  • Lung cancer probability in patients with CT-detected pulmonary nodules: a prespecified analysis of data from the NELSON trial of low-dose CT screening

    Nanda Horeweg;Joost van Rosmalen;Marjolein A Heuvelmans;Carlijn M van der Aalst

  • Systematic review of the staging performance of 18F-fluorodeoxyglucose positron emission tomography in esophageal cancer

    H.L. van Westreenen;M. Westerterp;P.M.M. Bossuyt;J. Pruim

  • Dabrafenib in patients with BRAF(V600E)-positive advanced non-small-cell lung cancer: a single-arm, multicentre, open-label, phase 2 trial

    David Planchard;Tae Min Kim;Julien Mazieres;Elisabeth Quoix

  • Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA.

    Rudolf S. N. Fehrmann;Ritsert C. Jansen;Jan H. Veldink;Harm-Jan Westra

  • Nodule management protocol of the NELSON randomised lung cancer screening trial

    Dong Ming Xu;Hester Gietema;Harry de Koning;René Vernhout

  • Dual Inhibition of EGFR with Afatinib and Cetuximab in Kinase Inhibitor-Resistant EGFR-Mutant Lung Cancer with and without T790M Mutations

    Yelena Y. Janjigian;Yelena Y. Janjigian;Egbert F. Smit;Harry J. M. Groen;Leora Horn

  • Preoperative chemotherapy in patients with resectable non-small cell lung cancer: results of the MRC LU22/NVALT 2/EORTC 08012 multicentre randomised trial and update of systematic review.

    David Gilligan;Marianne Nicolson;Ian Smith;Harry Groen

Frequent Co-Authors

Egbert F. Smit
Egbert F. Smit VU University Medical Center
Wim Timens
Wim Timens University Medical Center Groningen
Matthijs Oudkerk
Matthijs Oudkerk University of Groningen
Ed Schuuring
Ed Schuuring University Medical Center Groningen
Anne-Marie C. Dingemans
Anne-Marie C. Dingemans Erasmus University Rotterdam
Harry J. de Koning
Harry J. de Koning Erasmus University Rotterdam
Leon W.M.M. Terstappen
Leon W.M.M. Terstappen University of Twente
Anke van den Berg
Anke van den Berg University Medical Center Groningen
Dirkje S. Postma
Dirkje S. Postma University Medical Center Groningen
Klaas Kok
Klaas Kok University of Groningen

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