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Genetics

D-Index
129
Citations
90018
World Ranking
259
National Ranking
11

Medicine

D-Index
129
Citations
90229
World Ranking
2530
National Ranking
99

Overview

Lude Franke is affiliated with the University Medical Center Groningen in the Netherlands. Their research primarily focuses on biochemistry, genetics, and molecular biology, with substantial contributions in medicine. The scientist's work spans subfields including molecular biology, genetics, immunology, epidemiology, and cancer research.

Their research topics include genetic associations and epidemiology, single-cell and spatial transcriptomics, epigenetics and DNA methylation, bioinformatics and genomic networks, cancer genomics and diagnostics, genomics and rare diseases, and gut microbiota and health.

Among their recent publications are:

  • Large-scale association analyses identify host factors influencing human gut microbiome composition (2021, Nature Genetics)
  • Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals (2020, Nature Metabolism)
  • Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project (2022, Nature Genetics)
  • Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease (2022, Cell Genomics)
  • The single-cell eQTLGen consortium (2020, eLife)

Lude Franke frequently collaborates with several coauthors, including:

  • Cisca Wijmenga (60 coauthored works)
  • Harm-Jan Westra (57 coauthored works)
  • Patrick Deelen (48 coauthored works)
  • Serena Sanna (42 coauthored works)
  • Morris A. Swertz (41 coauthored works)

The scientist publishes extensively in various venues, with a notable number of publications in:

  • bioRxiv (Cold Spring Harbor Laboratory) - 47 publications
  • University of Groningen research database (University of Groningen / Centre for Information Technology) - 38 publications
  • Nature Communications - 10 publications
  • UNC Libraries - 10 publications
  • Nature Genetics - 7 publications

Best Publications

  • Biological insights from 108 schizophrenia-associated genetic loci

    Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Aiden Corvin;James T. R. Walters

  • Bayesian test for colocalisation between pairs of genetic association studies using summary statistics.

    Claudia Giambartolomei;Damjan Vukcevic;Eric E. Schadt;Lude Franke

  • Genetics of rheumatoid arthritis contributes to biology and drug discovery

    Yukinori Okada;Yukinori Okada;Di Wu;Di Wu;Di Wu;Gosia Trynka;Gosia Trynka;Towfique Raj;Towfique Raj

  • Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

    J Z Liu;S van Sommeren;H Huang;S C Ng

  • Defining the role of common variation in the genomic and biological architecture of adult human height

    Andrew R. Wood;Tonu Esko;Jian Yang;Sailaja Vedantam

  • Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity.

    Alexandra Zhernakova;Alexander Kurilshikov;Marc Jan Bonder;Ettje F. Tigchelaar

  • Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

    Urmo Võsa;Annique Claringbould;Annique Claringbould;Harm-Jan Westra;Marc Jan Bonder

  • Systematic identification of trans eQTLs as putative drivers of known disease associations

    Harm-Jan Westra;Marjolein J Peters;Tõnu Esko;Hanieh Yaghootkar

  • Large-scale association analyses identify host factors influencing human gut microbiome composition

    Alexander Kurilshikov;Carolina Medina-Gomez;Rodrigo Bacigalupe;Djawad Radjabzadeh

  • Genetic studies of body mass index yield new insights for obesity biology

    Adam E. Locke;Bratati Kahali;Sonja I. Berndt;Anne E. Justice

  • Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

    Carl A. Anderson;Gabrielle Boucher;Charlie W. Lees;Andre Franke

  • Genome-wide association study identifies 74 loci associated with educational attainment

    Aysu Okbay;Jonathan P. Beauchamp;Mark Alan Fontana;James J. Lee

  • Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

    Bjarni J. Vilhjálmsson;Jian Yang;Hilary K. Finucane;Alexander Gusev

  • Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases.

    Serena Sanna;Natalie R van Zuydam;Natalie R van Zuydam;Anubha Mahajan;Alexander Kurilshikov

  • Proton pump inhibitors affect the gut microbiome

    Floris Imhann;Marc Jan Bonder;Arnau Vich Vila;Jingyuan Fu

  • Multiple common variants for celiac disease influencing immune gene expression

    Patrick C. A. Dubois;Gosia Trynka;Lude Franke;Lude Franke;Karen A. Hunt

  • Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

    Aysu Okbay;Bart M L Baselmans;Jan-Emmanuel De Neve;Patrick Turley

  • GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment

    Cornelius A. Rietveld;Sarah E. Medland;Jaime Lane Derringer;Jian Yang

  • Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

    Gosia Trynka;Karen A Hunt;Nicholas A Bockett;Jihane Romanos

  • Genome-wide association study identifies 74 loci associated with educational attainment

    Aysu Okbay;Jonathan P. Beauchamp;Mark Alan Fontana;James J. Lee

Frequent Co-Authors

Cisca Wijmenga
Cisca Wijmenga University Medical Center Groningen
Tonu Esko
Tonu Esko University of Tartu
Harm-Jan Westra
Harm-Jan Westra University Medical Center Groningen
Andres Metspalu
Andres Metspalu University of Tartu
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam
Albert Hofman
Albert Hofman Harvard University
Olli T. Raitakari
Olli T. Raitakari Turku University Hospital
Johan G. Eriksson
Johan G. Eriksson National University of Singapore
Grant W. Montgomery
Grant W. Montgomery University of Queensland
Tune H. Pers
Tune H. Pers University of Copenhagen

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