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D-Index & Metrics

Chemistry

D-Index
58
Citations
15751
World Ranking
10470
National Ranking
2891

Overview

James P. Springer is affiliated with MSD in the United States and focuses primarily on research in the field of Materials Science, with specific emphasis on Materials Chemistry. Their work bridges key topics including Crystallization and Solubility Studies as well as X-ray Diffraction in Crystallography.

Springer's academic contributions are documented through publications that highlight their engagement with crystal structure analysis and related scientific methodologies. A notable recent publication includes:

  • CCDC 2276690: Experimental Crystal Structure Determination (2023) published in The Cambridge Structural Database

The publication venue reflects the specialized nature of Springer's research, with all works appearing in The Cambridge Structural Database, a source known for curated structural data in materials chemistry and crystallography.

Collaboration appears as a significant part of Springer's research approach. Frequent coauthors contributing alongside Springer include:

  • Jon Clardy
  • Richard H. Cox
  • Horace G. Cutler
  • Richard J. Cole

The collaboration with these researchers suggests interdisciplinary engagement within scientific circles focused on crystallography and materials analysis.

Springer's research expertise extends to applying X-ray diffraction techniques to characterize material structures, which is fundamental to understanding material properties and behavior in applied and theoretical contexts.

Best Publications

  • Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.

    A W Alberts;J Chen;G Kuron;V Hunt

  • Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists

    B. E. Evans;K. E. Rittle;M. G. Bock;R. M. DiPardo

  • Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1

    Manuel A. Navia;Paula M. D. Fitzgerald;Brian M. McKeever;Chih-Tai Leu

  • On the use of the O-methylmandelate ester for establishment of absolute configuration of secondary alcohols

    Barry M. Trost;John L. Belletire;Stephen Godleski;Patrick G. McDougal

  • Stromelysin‐1: Three‐dimensional structure of the inhibited catalytic domain and of the C‐truncated proenzyme

    Joseph W. Becker;Alice I. Marcy;Laura L. Rokosz;Melinda G. Axel

  • Crystallographic analysis of a complex between human immunodeficiency virus type 1 protease and acetyl-pepstatin at 2.0-A resolution.

    P. M. D. Fitzgerald;B. M. Mckeever;J. F. Vanmiddlesworth;J. P. Springer

  • Structure of saxitoxin

    E. J. Schantz;V. E. Ghazarossian;H. K. Schnoes;F. M. Strong

  • Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-A resolution

    Manuel A. Navia;Brian M. McKeever;James P. Springer;Tsau-Yen Lin

  • Thienothiopyran-2-sulfonamides: novel topically active carbonic anhydrase inhibitors for the treatment of glaucoma.

    Baldwin Jj;Ponticello Gs;Anderson Ps;Christy Me

  • The NMR structure of the inhibited catalytic domain of human stromelysin-1.

    Paul R. Gooley;John F. O'Connell;Alice I. Marcy;Gregory C. Cuca

  • A stereocontrolled synthesis of hydroxyethylene dipeptide isosteres using novel, chiral aminoalkyl epoxides and .gamma.-(aminoalkyl)-.gamma.-lactones

    Ben E. Evans;Kenneth E. Rittle;Carl F. Homnick;James P. Springer

  • Novel benzodiazepine receptor partial agonists: oxadiazolylimidazobenzodiazepines.

    Frank Watjen;Raymond Baker;Mogens Engelstoff;Richard Herbert

  • Structure of inositol monophosphatase, the putative target of lithium therapy.

    Roger Bone;James P. Springer;John R. Atack

  • Total synthesis of carpanone

    O. L. Chapman;M. R. Engel;J. P. Springer;J. C. Clardy

  • Chelation-controlled facially selective cyclocondensation reactions of chiral alkoxy aldehydes: syntheses of a mouse androgen and of a carbon-linked disaccharide

    Samuel J. Danishefsky;William H. Pearson;Daniel F. Harvey;Clarence J. Maring

  • Mycotoxins produced by Aspergillus fumigatus species isolated from molded silage.

    Cole Rj;Kirksey Jw;Dorner Jw;Wilson Dm

  • New isomeric classes of topically active ocular hypotensive carbonic anhydrase inhibitors: 5-substituted thieno[2,3-b]thiophene-2-sulfonamides and 5-substituted thieno[3,2-b]thiophene-2-sulfonamides.

    Prugh Jd;Hartman Gd;Mallorga Pj;McKeever Bm

  • Phosphinic acid inhibitors of D-alanyl-D-alanine ligase.

    W H Parsons;A A Patchett;H G Bull;W R Schoen

  • Crystallographie study of a β-lactam inhibitor complex with elastase at 1.84 Å resolution

    Manuel A. Navia;James P. Springer;Tsau-Yen Lin;Hollis R. Williams

  • Structural studies of metal binding by inositol monophosphatase: evidence for two-metal ion catalysis.

    Roger Bone;Lori Frank;James P. Springer;John R. Atack

Frequent Co-Authors

Leo A. Paquette
Leo A. Paquette The Ohio State University
Byron H. Arison
Byron H. Arison MSD (United States)
Alan P. Kozikowski
Alan P. Kozikowski StarWise Therapeutics LLC
Richard J. Cole
Richard J. Cole Agricultural Research Service
Arthur A. Patchett
Arthur A. Patchett MSD (United States)
Jon Clardy
Jon Clardy Harvard University
George D. Hartman
George D. Hartman Janssen (Belgium)
Deborah L. Zink
Deborah L. Zink Weizenbaum-Institut
Michael Williams
Michael Williams Uppsala University
Robert E. Schwartz
Robert E. Schwartz Cornell University

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