Wolfram Bode

Research.com Recognitions

• 2023 - Research.com Biology and Biochemistry in Germany Leader Award

Overview

Best Publications

• The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment.

  W Bode;I Mayr;U Baumann;R Huber

  1306
  Citations

• The cystatins: protein inhibitors of cysteine proteinases.

  Vito Turk;Wolfram Bode

  1169
  Citations

• Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXXHXXGXXH and Met-turn) and topologies and should be grouped into a common family, the 'metzincins'

  Wolfram Bode;Franz-Xaver Gomis-Rüth;Walter Stöckler

  1034
  Citations

• The structure of a complex of recombinant hirudin and human alpha-thrombin

  Timothy J. Rydel;K. G. Ravichandran;A. Tulinsky;Wolfram Bode

  1009
  Citations

• Structural basis of the activation and action of trypsin

  Robert Huber;Wolfram Bode

  1001
  Citations

• Handbook of metalloproteins

  Albrecht Messerschmidt;R. Huber;Thomas Poulos;Karl Wieghardt

  983
  Citations

• The metzincins--topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a superfamily of zinc-peptidases.

  W. Stöcker;F. Grams;U. Baumann;P. Reinemer

  893
  Citations

• The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships.

  Wolfram Bode;Dusan Turk;Andrej Karshikov

  885
  Citations

• The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors

  M. Marquart;J. Walter;J. Deisenhofer;W. Bode

  846
  Citations

• The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases.

  W. Bode;R. Engh;D. Musil;U. Thiele

  836
  Citations

• Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1.

  Franz-Xaver Gomis-Rüth;Klaus Maskos;Michael Betz;Andreas Bergner

  825
  Citations

• The refined 2.4 A X-ray crystal structure of recombinant human stefin B in complex with the cysteine proteinase papain: a novel type of proteinase inhibitor interaction.

  M T Stubbs;B Laber;W Bode;R Huber

  694
  Citations

• The refined crystal structure of bovine beta-trypsin at 1.8 A resolution. II. Crystallographic refinement, calcium binding site, benzamidine binding site and active site at pH 7.0.

  Wolfram Bode;Peter Schwager

  662
  Citations

• A player of many parts : the spotlight falls on thrombin's structure

  Milton T. Stubbs;Milton T. Stubbs;Wolfram Bode;Wolfram Bode

  649
  Citations

• Structure of human des(1-45) factor Xa at 2.2 A resolution.

  Kaillathe Padmanabhan;K.P. Padmanabhan;A. Tulinsky;Chang H. Park

  575
  Citations

• Human leukocyte and porcine pancreatic elastase: X-ray crystal structures, mechanism, substrate specificity, and mechanism-based inhibitors.

  Wolfram Bode;Edgar Meyer;James C. Powers

  566
  Citations

• Refined structure of the hirudin-thrombin complex.

  Timothy J. Rydel;Alexander Tulinsky;Wolfram Bode;Robert Huber

  518
  Citations

• Crystal structure of the thrombin-hirudin complex: a novel mode of serine protease inhibition.

  M. G. Grütter;J. P. Priestle;J. Rahuel;H. Grossenbacher

  500
  Citations

• X-ray crystallographic structure of the light-harvesting biliprotein C-phycocyanin from the thermophilic cyanobacterium Mastigocladus laminosus and its resemblance to globin structures

  Tilman Schirmer;Wolfram Bode;Robert Huber;Walter Sidler

  495
  Citations

• Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme.

  Klaus Maskos;Carlos Fernandez-Catalan;Robert Huber;Gleb P. Bourenkov

  487
  Citations