World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
56
Citations
8539
World Ranking
11917
National Ranking
3199

Biology and Biochemistry

D-Index
60
Citations
18895
World Ranking
11738
National Ranking
5049

Overview

Alireza R. Rezaie is affiliated with the Oklahoma Medical Research Foundation in the United States and specializes in the field of medicine with a strong focus on hematology. Their body of research includes 55 publications mainly centered on the biological mechanisms involved in blood coagulation and thrombosis.

The main topics covered in their work include:

  • Blood Coagulation and Thrombosis Mechanisms
  • Protease and Inhibitor Mechanisms
  • Venous Thromboembolism Diagnosis and Management
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Platelet Disorders and Treatments
  • Phagocytosis and Immune Regulation
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms

The scientist has contributed notably to the hematology subfield, with additional research in cancer research, immunology, genetics, and internal medicine. Their publications are often found in journals that specialize in thrombosis and hemostasis.

Frequent publication venues include:

  • Journal of Thrombosis and Haemostasis
  • Research and Practice in Thrombosis and Haemostasis
  • Thrombosis and Haemostasis
  • Arteriosclerosis Thrombosis and Vascular Biology
  • Blood Advances

Selected recent papers authored or coauthored by Alireza R. Rezaie are:

  • Anticoagulant and signaling functions of antithrombin, 2020, Journal of Thrombosis and Haemostasis
  • Thrombomodulin is essential for maintaining quiescence in vascular endothelial cells, 2021, Proceedings of the National Academy of Sciences
  • Analysis of protein missense alterations by combining sequence- and structure-based methods, 2020, Molecular Genetics & Genomic Medicine
  • L-SIGN is a receptor on liver sinusoidal endothelial cells for SARS-CoV-2 virus, 2021, JCI Insight
  • Antithrombin: An anticoagulant, anti-inflammatory and antibacterial serpin, 2020, Journal of Thrombosis and Haemostasis

Collaborative work is a prominent aspect of their career, with frequent coauthors including Indranil Biswas, Hemant Giri, Sumith R. Panicker, Bruno O. Villoutreix, and Yeling Lu. These partnerships reflect interdisciplinary and multi-institutional cooperation within their research areas.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells

    Jong-Sup Bae;Likui Yang;Chandrashekhara Manithody;Alireza R. Rezaie

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Protein C Inhibitor Is a Potent Inhibitor of the Thrombin-Thrombomodulin Complex

    Alireza R. Rezaie;Scott T. Cooper;Frank C. Church;Charles T. Esmon;Charles T. Esmon;Charles T. Esmon

  • Receptors of the protein C activation and activated protein C signaling pathways are colocalized in lipid rafts of endothelial cells

    Jong-Sup Bae;Likui Yang;Alireza R. Rezaie

  • The Endothelial Cell Protein C Receptor CELL SURFACE EXPRESSION AND DIRECT LIGAND BINDING BY THE SOLUBLE RECEPTOR

    Kenji Fukudome;Shinichiro Kurosawa;Deborah J. Stearns-Kurosawa;Xuhua He

  • Regulation of the protein C anticoagulant and antiinflammatory pathways.

    Alireza R. Rezaie

  • Vitronectin functions as a cofactor for rapid inhibition of activated protein C by plasminogen activator inhibitor-1. Implications for the mechanism of profibrinolytic action of activated protein C.

    Alireza R. Rezaie

  • Protease activated receptor 1 (PAR-1) activation by thrombin is protective in human pulmonary artery endothelial cells if endothelial protein C receptor is occupied by its natural ligand.

    Jong-Sup Bae;Alireza R. Rezaie

  • The function of calcium in protein C activation by thrombin and the thrombin-thrombomodulin complex can be distinguished by mutational analysis of protein C derivatives.

    A R Rezaie;C T Esmon

  • Identification of Basic Residues in the Heparin-binding Exosite of Factor Xa Critical for Heparin and Factor Va Binding

    Alireza R. Rezaie

  • Phosphatidylethanolamine augments factor VIIa-tissue factor activity: enhancement of sensitivity to phosphatidylserine

    Pierre F. Neuenschwander;Emma Bianco-Fisher;Alireza R. Rezaie;James H. Morrissey

  • Protease-activated receptor signalling by coagulation proteases in endothelial cells

    Alireza R. Rezaie

  • Activated protein C inhibits high mobility group box 1 signaling in endothelial cells

    Jong-Sup Bae;Alireza R. Rezaie

  • Polyphosphate elicits pro‐inflammatory responses that are counteracted by activated protein C in both cellular and animal models

    Jong-Sup Bae;Wonhwa Lee;Alireza R. Rezaie

  • Calcium Enhances Heparin Catalysis of the Antithrombin-Factor Xa Reaction by a Template Mechanism EVIDENCE THAT CALCIUM ALLEVIATES Gla DOMAIN ANTAGONISM OF HEPARIN BINDING TO FACTOR Xa

    Alireza R. Rezaie

  • Polyphosphate amplifies proinflammatory responses of nuclear proteins through interaction with receptor for advanced glycation end products and P2Y1 purinergic receptor

    Peyman Dinarvand;Seyed Mahdi Hassanian;Shabir H. Qureshi;Chandrashekhara Manithody

  • Prothrombin protects factor Xa in the prothrombinase complex from inhibition by the heparin-antithrombin complex.

    Alireza R. Rezaie

  • Anticoagulant and signaling functions of antithrombin.

    Alireza R. Rezaie;Alireza R. Rezaie;Hemant Giri

  • Substrate recognition by tissue factor-factor VIIa. Evidence for interaction of residues Lys165 and Lys166 of tissue factor with the 4-carboxyglutamate-rich domain of factor X.

    Qiuling Huang;Pierre F. Neuenschwander;Alireza R. Rezaie;James H. Morrissey;James H. Morrissey

Frequent Co-Authors

Charles T. Esmon
Charles T. Esmon Oklahoma Medical Research Foundation
Jong-Sup Bae
Jong-Sup Bae Kyungpook National University
James H. Morrissey
James H. Morrissey University of Michigan–Ann Arbor
Bruno O. Villoutreix
Bruno O. Villoutreix Université Paris Cité
Evelina Gatti
Evelina Gatti Aix-Marseille University
Leonidas C. Platanias
Leonidas C. Platanias Northwestern University
Hsing Jien Kung
Hsing Jien Kung Taipei Medical University
Maurizio Molinari
Maurizio Molinari Universita della Svizzera Italiana
Naomi L. Esmon
Naomi L. Esmon Oklahoma Medical Research Foundation
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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