What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Internal medicine
His primary scientific interests are in Tissue factor, Cell biology, Signal transduction, Thrombin and Biochemistry.
His Tissue factor study combines topics in areas such as Serine protease, Cancer research, Angiogenesis, Thromboplastin and Immunology.
Wolfram Ruf has included themes like Cancer cell and Metastasis in his Cancer research study.
Vascular remodelling in the embryo, Small intestine and Gut flora is closely connected to Cell surface receptor in his research, which is encompassed under the umbrella topic of Cell biology.
The various areas that he examines in his Signal transduction study include Endocrinology, Protease-Activated Receptor 1, Molecular biology, Internal medicine and Growth factor.
Many of his studies on Thrombin involve topics that are commonly interrelated, such as Cell signaling.
His most cited work include:
- Activation of Endothelial Cell Protease Activated Receptor 1 by the Protein C Pathway (736 citations)
- The structural biology of expression and function of tissue factor. (515 citations)
- Lethal E. coli septic shock is prevented by blocking tissue factor with monoclonal antibody. (377 citations)
What are the main themes of his work throughout his whole career to date?
Wolfram Ruf focuses on Tissue factor, Cell biology, Cancer research, Signal transduction and Biochemistry.
Wolfram Ruf has researched Tissue factor in several fields, including Immunology, Molecular biology, Thrombin and Thromboplastin.
His Cell biology study combines topics from a wide range of disciplines, such as Receptor, Integrin and Endothelial protein C receptor.
His Cancer research research is multidisciplinary, incorporating elements of Cancer cell, Cancer and Metastasis.
His work deals with themes such as Endocrinology, Internal medicine, Cytokine, Phosphorylation and Protease-activated receptor, which intersect with Signal transduction.
His study in Biochemistry is interdisciplinary in nature, drawing from both Factor VII and Factor X.
He most often published in these fields:
- Tissue factor (66.19%)
- Cell biology (38.92%)
- Cancer research (24.72%)
What were the highlights of his more recent work (between 2017-2021)?
- Tissue factor (66.19%)
- Cell biology (38.92%)
- Cancer research (24.72%)
In recent papers he was focusing on the following fields of study:
Wolfram Ruf mainly investigates Tissue factor, Cell biology, Cancer research, Signal transduction and Internal medicine.
His Tissue factor research integrates issues from Inflammation, Cell signaling, Protease-activated receptor and Thromboplastin.
Wolfram Ruf combines subjects such as Endothelial protein C receptor, Integrin and Transcription factor with his study of Cell biology.
His Cancer research research incorporates themes from Cell and Metastasis.
His studies deal with areas such as Endocrinology and Cardiology as well as Internal medicine.
The concepts of his Coagulation study are interwoven with issues in Hemostasis, Thrombosis and Thrombin.
Between 2017 and 2021, his most popular works were:
- Tissue factor at the crossroad of coagulation and cell signaling. (50 citations)
- Tissue factor at the crossroad of coagulation and cell signaling. (50 citations)
- Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2. (43 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Internal medicine
His primary areas of investigation include Tissue factor, Cancer research, Cell biology, Thromboplastin and Coagulation.
The Tissue factor study combines topics in areas such as Inflammation, PTEN and Proteases.
His research investigates the connection with Proteases and areas like Protease-activated receptor which intersect with concerns in Innate immune system.
The Cancer research study which covers Signal transduction that intersects with Immunotherapy, Cytotoxic T cell and Tissue factor pathway inhibitor.
His studies in Cell biology integrate themes in fields like Endothelial protein C receptor and Integrin.
His research on Coagulation also deals with topics like
- Thrombosis which connect with Mediator, Cancer, Bioinformatics and Position paper,
- Platelet that intertwine with fields like Antibody, Monocyte, Complement component 5 and Immunoglobulin G.
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