Wolfram Ruf

Overview

Best Publications

• Activation of Endothelial Cell Protease Activated Receptor 1 by the Protein C Pathway

  Matthias Riewald;Ramona J. Petrovan;Aaron Donner;Barbara M. Mueller

  1217
  Citations

• The structural biology of expression and function of tissue factor.

  Thomas S Edgington;Nigel Mackman;Korbinian Brand;Wolfram Ruf

  810
  Citations

• Lethal E. coli septic shock is prevented by blocking tissue factor with monoclonal antibody.

  F. B. Taylor;A. Chang;W. Ruf;J. H. Morrissey

  694
  Citations

• Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis.

  Barbara M. Mueller;Ralph A. Reisfeld;Thomas S. Edgington;Wolfram Ruf

  558
  Citations

• A ROLE FOR TISSUE FACTOR IN CELL ADHESION AND MIGRATION MEDIATED BY INTERACTION WITH ACTIN-BINDING PROTEIN 280

  Ilka Ott;Edgar G. Fischer;Yohei Miyagi;Barbara M. Mueller

  447
  Citations

• Mechanistic coupling of protease signaling and initiation of coagulation by tissue factor

  Matthias Riewald;Wolfram Ruf

  446
  Citations

• Regulation of angiogenesis by tissue factor cytoplasmic domain signaling

  Mattias Belting;Michael I Dorrell;Staffan Sandgren;Edith Aguilar

  443
  Citations

• Inflammation, obesity, and thrombosis

  Fahumiya Samad;Wolfram Ruf

  413
  Citations

• Disulfide isomerization switches tissue factor from coagulation to cell signaling.

  Jasimuddin Ahamed;Henri H. Versteeg;Marjolein Kerver;Vivien M. Chen

  407
  Citations

• Inhibition of tissue factor signaling suppresses tumor growth

  Henri H. Versteeg;Florence Schaffner;Marjolein Kerver;Helle H. Petersen

  406
  Citations

• Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice

  Ana M. Gil-Bernabé;Špela Ferjančič;Monika Tlalka;Lei Zhao

  388
  Citations

• Protease-activated receptor 2 signaling in inflammation

  Andrea S. Rothmeier;Wolfram Ruf

  358
  Citations

• STRUCTURAL BIOLOGY OF TISSUE, FACTOR, THE INITIATOR OF THROMBOGENESIS IN VIVO

  Wolfram Ruf;Thomas S. Edgington

  354
  Citations

• Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2–mediated heparin-binding EGF signaling in endothelial cells

  Katrin J. Svensson;Paulina Kucharzewska;Helena C. Christianson;Stefan Sköld

  353
  Citations

• Phospholipid-independent and -dependent interactions required for tissue factor receptor and cofactor function.

  W Ruf;A Rehemtulla;J H Morrissey;T S Edgington

  351
  Citations

• Requirement for binding of catalytically active factor VIIa in tissue factor-dependent experimental metastasis

  B M Mueller;W Ruf

  348
  Citations

• Dendritic cell PAR1–S1P3 signalling couples coagulation and inflammation

  Frank Niessen;Florence Schaffner;Christian Furlan-Freguia;Rafal Pawlinski

  341
  Citations

• Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis.

  Xiaoli Shi;Beena Gangadharan;Lawrence F Brass;Wolfram Ruf

  326
  Citations

• Tissue factor and PAR1 promote microbiota-induced intestinal vascular remodelling

  Christoph Reinhardt;Mattias Bergentall;Thomas U. Greiner;Florence Schaffner

  322
  Citations

• Functional tissue factor is entirely cell surface expressed on lipopolysaccharide-stimulated human blood monocytes and a constitutively tissue factor-producing neoplastic cell line.

  Thomas A. Drake;Wolfram Ruf;James H. Morrissey;Thomas S. Edgington

  312
  Citations