World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
17770
World Ranking
18544
National Ranking
189

Overview

Orit Kollet is a researcher affiliated with the Weizmann Institute of Science in Israel, specializing primarily in Medicine. Their work encompasses several subfields including Immunology, Hematology, Pulmonary and Respiratory Medicine, Oncology, and Cell Biology. The scope of their research includes topics such as Hematopoietic Stem Cell Transplantation, Neonatal Respiratory Health Research, Immune Response and Inflammation, Childhood Cancer Survivors' Quality of Life, Neutrophil, Myeloperoxidase and Oxidative Mechanisms, Sepsis Diagnosis and Treatment, and Mesenchymal stem cell research.

Their recent publications demonstrate a diverse research interest with implications across cellular and molecular medicine. Notable papers include:

  • Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling (2020, Nature Communications)
  • Bone marrow regeneration requires mitochondrial transfer from donor Cx43-expressing hematopoietic progenitors to stroma (2020, Blood)
  • Redefining metalloproteases specificity through network proteolysis (2023, Trends in Molecular Medicine)
  • Enhancing uterine receptivity for embryo implantation through controlled collagenase intervention (2024, Life Science Alliance)
  • Altered extracellular matrix structure and elevated stiffness in a brain organoid model for disease (2025, Nature Communications)

Among frequent coauthors collaborating with Kollet are Tsvee Lapidot, Eman Khatib-Massalha, Ekaterina Petrovich-Kopitman, Irit Sagi, and Priyasmita Chakrabarti. These collaborations further support work in related biomedical areas and indicate ongoing contributions to multi-author research projects.

The researcher's publications have appeared often in journals including Nature Communications, Blood, Leukemia, Trends in Molecular Medicine, and Life Science Alliance. These venues reflect a strong focus on translational and clinical biomedical science.

Best Publications

  • Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4

    Amnon Peled;Isabelle Petit;Orit Kollet;Michal Magid

  • Targeted Disruption of the Mouse Caspase 8 Gene Ablates Cell Death Induction by the TNF Receptors, Fas/Apo1, and DR3 and Is Lethal Prenatally

    Eugene E Varfolomeev;Marcus Schuchmann;Victor Luria;Nuchanard Chiannilkulchai

  • How do stem cells find their way home

    Tsvee Lapidot;Ayelet Dar;Orit Kollet

  • The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice.

    Amnon Peled;Orit Kollet;Tanya Ponomaryov;Isabelle Petit

  • Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells

    Orit Kollet;Ayelet Dar;Shoham Shivtiel;Alexander Kalinkovich

  • HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver.

    Orit Kollet;Shoham Shivtiel;Yuan Qing Chen;Jenny Suriawinata

  • The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repopulation of transplanted immune-deficient NOD/SCID and NOD/SCID/B2m(null) mice.

    T Lapidot;O Kollet

  • Distinct bone marrow blood vessels differentially regulate haematopoiesis

    Tomer Itkin;Shiri Gur-Cohen;Joel A. Spencer;Amir Schajnovitz

  • CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrow.

    Abraham Avigdor;Polina Goichberg;Shoham Shivtiel;Ayelet Dar

  • Mutual, reciprocal SDF-1/CXCR4 interactions between hematopoietic and bone marrow stromal cells regulate human stem cell migration and development in NOD/SCID chimeric mice.

    Ayelet Dar;Orit Kollet;Tsvee Lapidot

  • Engraftment in nonobese diabetic severe combined immunodeficient mice of human CD34(+) cord blood cells after ex vivo expansion: evidence for the amplification and self-renewal of repopulating stem cells.

    Wanda Piacibello;Fiorella Sanavio;Antonella Severino;Alessandra Danè

  • Rapid and efficient homing of human CD34(+)CD38(-/low)CXCR4(+) stem and progenitor cells to the bone marrow and spleen of NOD/SCID and NOD/SCID/B2m(null) mice.

    Orit Kollet;Asaf Spiegel;Amnon Peled;Isabelle Petit

  • Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells.

    Ayelet Dar;Polina Goichberg;Vera Shinder;Alexander Kalinkovich

  • Stem Cell Mobilization

    Michele H. Cottler-Fox;Tsvee Lapidot;Isabelle Petit;Orit Kollet

  • Reactive oxygen species regulate hematopoietic stem cell self-renewal, migration and development, as well as their bone marrow microenvironment.

    Aya Ludin;Shiri Gur-Cohen;Karin Golan;Kerstin B. Kaufmann

  • Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells

    Ayelet Dar;Amir Schajnovitz;Kfir Lapid;Alexander Kalinkovich

  • β2 Microglobulin-deficient (B2mnull) NOD/SCID mice are excellent recipients for studying human stem cell function

    Orit Kollet;Orit Kollet;Amnon Peled;Amnon Peled;Tamara Byk;Tamara Byk;Herzl Ben-Hur;Herzl Ben-Hur

  • Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow.

    Aya Ludin;Tomer Itkin;Shiri Gur-Cohen;Alexander Mildner

  • NOD/LtSz-Rag1null Mice: An Immunodeficient and Radioresistant Model for Engraftment of Human Hematolymphoid Cells, HIV Infection, and Adoptive Transfer of NOD Mouse Diabetogenic T Cells

    Leonard D. Shultz;Pamela A. Lang;Sherri W. Christianson;Bruce Gott

  • S1P promotes murine progenitor cell egress and mobilization via S1P1-mediated ROS signaling and SDF-1 release.

    Karin Golan;Yaron Vagima;Aya Ludin;Tomer Itkin

Frequent Co-Authors

Tsvee Lapidot
Tsvee Lapidot Weizmann Institute of Science
Michel Revel
Michel Revel Weizmann Institute of Science
Arnon Nagler
Arnon Nagler Sheba Medical Center
Wolfram Ruf
Wolfram Ruf Johannes Gutenberg University of Mainz
Amnon Peled
Amnon Peled Hebrew University of Jerusalem
Ronen Alon
Ronen Alon Weizmann Institute of Science
Charles T. Esmon
Charles T. Esmon Oklahoma Medical Research Foundation
Irit Sagi
Irit Sagi Weizmann Institute of Science
Ralf H. Adams
Ralf H. Adams Max Planck Society
Ayelet Erez
Ayelet Erez Weizmann Institute of Science

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