What is he best known for?
The fields of study he is best known for:
James A. Huntington spends much of his time researching Biochemistry, Serpin, Protease, Antithrombin and Conformational change.
His work carried out in the field of Biochemistry brings together such families of science as Antibody, Thrombin and Cell biology.
The various areas that James A. Huntington examines in his Serpin study include Peptide sequence and Stereochemistry.
Protease is often connected to Protein structure in his work.
As a member of one scientific family, James A. Huntington mostly works in the field of Antithrombin, focusing on Proteases and, on occasion, Allosteric regulation.
Conformational change is a subfield of Biophysics that James A. Huntington explores.
His most cited work include:
- Structure of a serpin–protease complex shows inhibition by deformation (920 citations)
- Structure of the antithrombin–thrombin–heparin ternary complex reveals the antithrombotic mechanism of heparin (289 citations)
- Serpins in thrombosis, hemostasis and fibrinolysis (243 citations)
What are the main themes of his work throughout his whole career to date?
Biochemistry, Serpin, Thrombin, Antithrombin and Protein structure are his primary areas of study.
His Biochemistry research is multidisciplinary, incorporating perspectives in alpha-2-Macroglobulin and Biophysics.
His biological study spans a wide range of topics, including Proteases, Peptide sequence, Protein C inhibitor and Cell biology.
His research in Thrombin intersects with topics in Coagulation, Zymogen and Allosteric regulation.
James A. Huntington interconnects Conformational change and Stereochemistry in the investigation of issues within Antithrombin.
His study looks at the intersection of Protein structure and topics like Binding site with Plasma protein binding and Cofactor binding.
He most often published in these fields:
- Biochemistry (49.15%)
- Serpin (40.68%)
- Thrombin (38.14%)
What were the highlights of his more recent work (between 2010-2021)?
- Biochemistry (49.15%)
- Thrombin (38.14%)
- Serpin (40.68%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Biochemistry, Thrombin, Serpin, Protease and Prothrombinase.
His Peptide sequence, Conformational change and Antithrombin deficiency study in the realm of Biochemistry interacts with subjects such as Frame.
His Thrombin research integrates issues from Biophysics and Fibrin.
His study in Serpin focuses on Reactive center in particular.
James A. Huntington has included themes like Antithrombin and Classical complement pathway in his Protease study.
The study incorporates disciplines such as Genetics, Gene and Molecular biology in addition to Antithrombin.
Between 2010 and 2021, his most popular works were:
- Serpin structure, function and dysfunction. (195 citations)
- Molecular basis of α1‐antitrypsin deficiency revealed by the structure of a domain‐swapped trimer (117 citations)
- Design and characterization of an APC-specific serpin for the treatment of hemophilia (74 citations)
In his most recent research, the most cited papers focused on:
His primary areas of study are Thrombin, Biochemistry, Protease, Serpin and Prothrombinase.
The Thrombin study combines topics in areas such as Protein C, Coagulation and Fibrin.
Many of his research projects under Biochemistry are closely connected to Porphyromonas gingivalis and Gingipain K with Porphyromonas gingivalis and Gingipain K, tying the diverse disciplines of science together.
His studies deal with areas such as Biophysics, Antithrombin and Cell biology as well as Protease.
His work deals with themes such as Protein superfamily, Conformational change and Function, which intersect with Antithrombin.
His work on Serpin is being expanded to include thematically relevant topics such as In vivo.
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