D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics D-index 62 Citations 20,406 100 World Ranking 2134 National Ranking 960

Research.com Recognitions

Awards & Achievements

2012 - Fellow of the American Association for the Advancement of Science (AAAS)

1997 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

His main research concerns Molecular biology, Genetics, Biochemistry, Chromatin and Acetylation. He combines subjects such as Acetyltransferase, Topoisomerase and Mutant with his study of Molecular biology. His research links Computational biology with Genetics.

His work deals with themes such as Histone and Gene silencing, which intersect with Chromatin. His research investigates the connection between Acetylation and topics such as Saccharomyces cerevisiae that intersect with issues in Acetyltransferase complex, Ogden Syndrome, Chloramphenicol acetyltransferase and Derepression. His Gene study combines topics from a wide range of disciplines, such as DNA and Protein–protein interaction.

His most cited work include:

  • The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest. (1363 citations)
  • The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases. (821 citations)
  • The two-hybrid system: an assay for protein-protein interactions (648 citations)

What are the main themes of his work throughout his whole career to date?

Biochemistry, Genetics, Molecular biology, Saccharomyces cerevisiae and Mutant are his primary areas of study. His is involved in several facets of Biochemistry study, as is seen by his studies on Acetylation, Histone, Acetyltransferase, HAT1 and NAD+ kinase. His study in Genetics concentrates on Gene, Gene silencing, Chromatin, Origin recognition complex and DNA replication.

The Molecular biology study which covers Topoisomerase that intersects with DNA supercoil, Eukaryotic DNA replication, Camptothecin and Schizosaccharomyces pombe. The various areas that Rolf Sternglanz examines in his Saccharomyces cerevisiae study include Transcription factor, DNA-binding protein, Transcription and Protein biosynthesis. His study explores the link between Mutant and topics such as Glycoprotein that cross with problems in Glycosylation.

He most often published in these fields:

  • Biochemistry (43.56%)
  • Genetics (35.64%)
  • Molecular biology (32.67%)

What were the highlights of his more recent work (between 2005-2017)?

  • Saccharomyces cerevisiae (29.70%)
  • Biochemistry (43.56%)
  • Genetics (35.64%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Saccharomyces cerevisiae, Biochemistry, Genetics, Histone and Cell biology. To a larger extent, Rolf Sternglanz studies Gene with the aim of understanding Saccharomyces cerevisiae. His study in Chromatin, Sirtuin, Binding site and Deacetylase activity falls under the purview of Biochemistry.

All of his Genetics and Gene silencing and Mutation investigations are sub-components of the entire Genetics study. His work in Histone is not limited to one particular discipline; it also encompasses Acetylation. Mutant is closely connected to Molecular biology in his research, which is encompassed under the umbrella topic of Histone octamer.

Between 2005 and 2017, his most popular works were:

  • SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis (451 citations)
  • NAD + -dependent deacetylation of H4 lysine 16 by class III HDACs (217 citations)
  • Structural Basis of Inhibition of the Human NAD+-Dependent Deacetylase SIRT5 by Suramin (174 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

Rolf Sternglanz focuses on Biochemistry, Histone, Chromatin, SIRT3 and Acetylation. His research brings together the fields of Rational design and Biochemistry. His studies deal with areas such as Protein biosynthesis, Messenger RNA, Saccharomyces cerevisiae and Kinase activity as well as Chromatin.

Rolf Sternglanz is researching SIRT3 as part of the investigation of Sirtuin and Genetics. Rolf Sternglanz interconnects Lysine and Binding site in the investigation of issues within Acetylation. His research integrates issues of Histone methyltransferase, Histone code, Histone H2A, Histone H1 and Gene silencing in his study of Histone H4.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest.

Cheng-Ting Chien;Paul L. Bartel;Rolf Sternglanz;Stanley Fields.
Proceedings of the National Academy of Sciences of the United States of America (1991)

2316 Citations

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases.

Joseph Landry;Ann Sutton;Stefan T. Tafrov;Ryan C. Heller.
Proceedings of the National Academy of Sciences of the United States of America (2000)

1328 Citations

The two-hybrid system: an assay for protein-protein interactions

Stanley Fields;Rolf Sternglanz.
Trends in Genetics (1994)

1039 Citations

DNA topoisomerase II mutant of Saccharomyces cerevisiae: topoisomerase II is required for segregation of daughter molecules at the termination of DNA replication.

Stephen Dinardo;Karen Voelkel;Rolf Sternglanz.
Proceedings of the National Academy of Sciences of the United States of America (1984)

902 Citations

Elimination of false positives that arise in using the two-hybrid system.

P. Bartel;Cheng-Ting Chien;R. Sternglanz;S. Fields.
BioTechniques (1993)

765 Citations

Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose

Kirk G. Tanner;Joseph Landry;Rolf Sternglanz;John M. Denu.
Proceedings of the National Academy of Sciences of the United States of America (2000)

704 Citations

SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis

Alejandro Vaquero;Michael B. Scher;Dong Hoon Lee;Ann Sutton.
Genes & Development (2006)

644 Citations

Characterization of a “silencer” in yeast: A DNA sequence with properties opposite to those of a transcriptional enhancer

Andrea H. Brand;Linda Breeden;Judith Abraham;Rolf Sternglanz.
Cell (1985)

639 Citations

Perinuclear localization of chromatin facilitates transcriptional silencing

Erik D. Andrulis;Aaron M. Neiman;David C. Zappulla;Rolf Sternglanz.
Nature (1998)

593 Citations

Escherichia coli DNA topoisomerase I mutants have compensatory mutations in DNA gyrase genes

Stephen Dinardo;Karen A. Voelkel;Rolf Sternglanz;Ann E. Reynolds.
Cell (1982)

591 Citations

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