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Chemistry

D-Index
71
Citations
18568
World Ranking
5526
National Ranking
340

Overview

Yoshiaki Kawashima is affiliated with Gifu Pharmaceutical University in Japan and conducts research primarily in the fields of Materials Science and Pharmacology, Toxicology, and Pharmaceutics. Their work explores topics related to nanoparticle-based drug delivery, dendrimers and hyperbranched polymers, and advanced drug delivery systems, among others.

Kawashima's recent publications reflect a strong focus on drug delivery technologies and polymer-based materials. Notable recent papers include:

  • Inclusion complex based on N-acetyl-L-cysteine and arginine modified hydroxypropyl-β-cyclodextrin for oral insulin delivery (2020), published in Carbohydrate Polymers
  • Multifunctional micelles self-assembled from hyaluronic acid conjugate for enhancing anti-tumor effect of paclitaxel (2020), published in Reactive and Functional Polymers
  • A Chitosan-Based Micellar System as Nanocarrier For the Delivery of Paclitaxel (2020), published in Polymers
  • Tumor-targeting and redox-sensitive micelles based on hyaluronic acid conjugate for delivery of paclitaxel (2020), published in Journal of Biomaterials Applications
  • Crystallographic evaluation of the conformation of quetiapine included in β-cyclodextrin (2020), published in International Journal of Pharmaceutics

Their research contributions have appeared in several publication venues, including:

  • Carbohydrate Polymers
  • Reactive and Functional Polymers
  • Polymers
  • Journal of Biomaterials Applications
  • International Journal of Pharmaceutics

Frequent collaborators in Kawashima's work include Na Liang, Shaoping Sun, Peng-Fei Yan, Shupeng Li, and Han Yang. These collaborations demonstrate engagement with other researchers specializing in related areas, particularly in polymer science and drug delivery applications.

The core research topics covered in Kawashima's work encompass:

  • Nanoparticle-Based Drug Delivery
  • Dendrimers and Hyperbranched Polymers
  • Drug Solubility and Delivery Systems
  • Nanoplatforms for Cancer Theranostics
  • Advanced Drug Delivery Systems
  • Polymer Surface Interaction Studies
  • Crystallization and Solubility Studies

Main and subfields of study for Kawashima include:

  • Materials Science
  • Pharmacology, Toxicology and Pharmaceutics
  • Biomaterials
  • Pharmaceutical Science
  • Polymers and Plastics
  • Biomedical Engineering
  • Surfaces, Coatings and Films

The research focus of Kawashima reflects an interdisciplinary approach combining materials science and pharmaceutical sciences to address challenges in drug delivery and therapeutic applications.

Best Publications

  • Mucoadhesive nanoparticulate systems for peptide drug delivery.

    Hirofumi Takeuchi;Hiromitsu Yamamoto;Yoshiaki Kawashima

  • Preparations of biodegradable nanospheres of water-soluble and insoluble drugs with D,L-lactide/glycolide copolymer by a novel spontaneous emulsification solvent diffusion method, and the drug release behavior

    Toshiyuki Niwa;Hirofumi Takeuchi;Tomoaki Hino;Noriyuki Kunou

  • Enteral absorption of insulin in rats from mucoadhesive chitosan-coated liposomes.

    Hirofumi Takeuchi;Hiromitsu Yamamoto;Toshiyuki Niwa;Tomoaki Hino

  • Preparation of poly(dl-lactide-co-glycolide) nanoparticles by modified spontaneous emulsification solvent diffusion method

    Hideki Murakami;Masao Kobayashi;Hirofumi Takeuchi;Yoshiaki Kawashima

  • Biodegradable Nanoparticles for Targeted Drug Delivery in Treatment of Inflammatory Bowel Disease

    Alf Lamprecht;Nathalie Ubrich;Hiromitsu Yamamoto;Ulrich Schäfer

  • Surface-modified PLGA nanosphere with chitosan improved pulmonary delivery of calcitonin by mucoadhesion and opening of the intercellular tight junctions

    Hiromitsu Yamamoto;Yoshio Kuno;Shohei Sugimoto;Hirofumi Takeuchi

  • Biodegradable nanoparticles loaded with insulin-phospholipid complex for oral delivery: preparation, in vitro characterization and in vivo evaluation.

    Unknown

  • Hollow Microspheres for Use as a Floating Controlled Drug Delivery System in the Stomach

    Y. Kawashima;T. Niwa;H. Takeuchi;T. Hino

  • Mucoadhesive DL-Lactide/Glycolide Copolymer Nanospheres Coated with Chitosan to Improve Oral Delivery of Elcatonin

    Yoshiaki Kawashima;Hiromitsu Yamamoto;Hirofumi Takeuchi;Yoshio Kuno

  • Spherical crystallization: direct spherical agglomeration of salicylic Acid crystals during crystallization.

    Yoshiaki Kawashima;Motonari Okumura;Hideo Takenaka

  • Pulmonary delivery of insulin with nebulized DL-lactide/glycolide copolymer (PLGA) nanospheres to prolong hypoglycemic effect.

    Yoshiaki Kawashima;Hiromitsu Yamamoto;Hirofumi Takeuchi;Satoshi Fujioka

  • Solid dispersion particles of amorphous indomethacin with fine porous silica particles by using spray-drying method.

    Hirofumi Takeuchi;Shinsuke Nagira;Hiromitsu Yamamoto;Yoshiaki Kawashima

  • Preparation of Controlled-Release Microspheres of Ibuprofen With Acrylic Polymers by a Novel Quasi-Emulsion Solvent Diffusion Method

    Y. Kawashima;T. Niwa;T. Handa;H. Takeuchi

  • Properties of a peptide containing dl-lactide/glycolide copolymer nanospheres prepared by novel emulsion solvent diffusion methods

    Yoshiaki Kawashima;Hiromitsu Yamamoto;Hirofumi Takeuchi;Tomoaki Hino

  • Evaluation of circulation profiles of liposomes coated with hydrophilic polymers having different molecular weights in rats

    Hirofumi Takeuchi;Hiroyuki Kojima;Hiromitsu Yamamoto;Yoshiaki Kawashima

  • Preparation of multiple unit hollow microspheres (microballoons) with acrylic resin containing tranilast and their drug release characteristics (in vitro) and floating behavior (in vivo)

    Yoshiaki Kawashima;Toshiyuki Niwa;Hirofumi Takeuchi;Tomoaki Hino

  • Effectiveness of submicron-sized, chitosan-coated liposomes in oral administration of peptide drugs.

    Hirofumi Takeuchi;Yuji Matsui;Hikaru Sugihara;Hiromitsu Yamamoto

  • Nanoparticles enhance therapeutic efficiency by selectively increased local drug dose in experimental colitis in rats

    Alf Lamprecht;Hiromitsu Yamamoto;Hirofumi Takeuchi;Yoshiaki Kawashima

  • Novel Method for the Preparation of Controlled-Release Theophylline Granules Coated with a Polyelectrolyte Complex of Sodium Polyphosphate-Chitosan

    Yoshiaki Kawashima;Tetsurou Handa;Akihiro Kasai;Hideo Takenaka

  • Improved cellular uptake of chitosan-modified PLGA nanospheres by A549 cells.

    Unknown

  • Nanoparticulate systems for improved drug delivery

    Yoshiaki Kawashima

  • Particle design of poorly water-soluble drug substances using supercritical fluid technologies.

    Takehiko Yasuji;Hirofumi Takeuchi;Yoshiaki Kawashima

Frequent Co-Authors

Hirofumi Takeuchi
Hirofumi Takeuchi Gifu Pharmaceutical University
Kenji Sunagawa
Kenji Sunagawa Kyushu University
Kensuke Egashira
Kensuke Egashira Kyushu University
Peter York
Peter York University of Bradford
Kohei M. Itoh
Kohei M. Itoh Keio University
Yoshinori Nozawa
Yoshinori Nozawa Gifu University
Toshiyuki Tanaka
Toshiyuki Tanaka Hyogo University of Health Sciences
Takashi Suzuki
Takashi Suzuki Tohoku University

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