David H. Cribbs

Overview

Best Publications

• A microfluidic culture platform for CNS axonal injury, regeneration and transport

  Anne M. Taylor;Mathew Blurton-Jones;Seog Woo Rhee;David H. Cribbs

  1328
  Citations

• Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

  Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  1090
  Citations

• Aβ Immunotherapy Leads to Clearance of Early, but Not Late, Hyperphosphorylated Tau Aggregates via the Proteasome

  Salvatore Oddo;Lauren Billings;J.Patrick Kesslak;David H. Cribbs

  1018
  Citations

• Structure‐Activity Analyses of β‐Amyloid Peptides: Contributions of the β25–35 Region to Aggregation and Neurotoxicity

  Christian J. Pike;Andrea J. Walencewicz-Wasserman;Joseph Kosmoski;David H. Cribbs

  961
  Citations

• Gene expression changes in the course of normal brain aging are sexually dimorphic.

  Nicole C. Berchtold;David H. Cribbs;Paul D. Coleman;Joseph Rogers

  692
  Citations

• Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study

  David H Cribbs;Nicole C Berchtold;Victoria Perreau;Paul D Coleman

  548
  Citations

• Blocking IL-1 Signaling Rescues Cognition, Attenuates Tau Pathology, and Restores Neuronal β-Catenin Pathway Function in an Alzheimer’s Disease Model

  Masashi Kitazawa;David Cheng;Michelle R. Tsukamoto;Maya A. Koike

  467
  Citations

• Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

  Eric M Reiman;Joseph F Arboleda-Velasquez;Yakeel T Quiroz;Matthew J Huentelman

  461
  Citations

• Microfluidic multi-compartment device for neuroscience research

  Noo Li Jeon;Carl W Cotman

  420
  Citations

• Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

  David C. Whitcomb;Jessica LaRusch;Alyssa M. Krasinskas;Lambertus Klei

  405
  Citations

• Reduction of Soluble Aβ and Tau, but Not Soluble Aβ Alone, Ameliorates Cognitive Decline in Transgenic Mice with Plaques and Tangles

  Salvatore Oddo;Vitaly Vasilevko;Antonella Caccamo;Masashi Kitazawa

  402
  Citations

• Adjuvant‐dependent modulation of Th1 and Th2 responses to immunization with β‐amyloid

  David H. Cribbs;Anahit Ghochikyan;Vitaly Vasilevko;Mike Tran

  394
  Citations

• Patterned cell culture inside microfluidic devices

  Seog Woo Rhee;Anne M. Taylor;Christina H. Tu;David H. Cribbs

  366
  Citations

• A novel Alzheimer disease locus located near the gene encoding tau protein

  G. Jun;C. A. Ibrahim-Verbaas;M. Vronskaya;J-C Lambert;J-C Lambert;J-C Lambert

  322
  Citations

• Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease.

  Nicole C. Berchtold;Paul D. Coleman;Paul D. Coleman;David H. Cribbs;Joseph Rogers

  318
  Citations

• Prototype Alzheimer’s Disease Vaccine Using the Immunodominant B Cell Epitope from β-Amyloid and Promiscuous T Cell Epitope Pan HLA DR-Binding Peptide

  Michael G. Agadjanyan;Anahit Ghochikyan;Irina Petrushina;Vitaly Vasilevko

  305
  Citations

• Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid

  Kathryn E Nichol;Wayne W Poon;Anna I Parachikova;David H Cribbs

  297
  Citations

• Brain-Derived Neurotrophic Factor-Dependent Synaptic Plasticity Is Suppressed by Interleukin-1β via p38 Mitogen-Activated Protein Kinase

  Liqi Tong;G. Aleph Prieto;Enikö A. Kramár;Erica D. Smith

  292
  Citations

• Localization and Cell Association of C1q in Alzheimer's Disease Brain

  Arman Afagh;Brian J. Cummings;David H. Cribbs;Carl W. Cotman

  283
  Citations

• Novel Aβ peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease

  Jun Zhou;María I Fonseca;Rakez Kayed;Irma Arias Hernández

  33
  Citations