Mathew Blurton-Jones

Overview

Best Publications

• Microglia states and nomenclature: A field at its crossroads

  Unknown

  2095
  Citations

• A microfluidic culture platform for CNS axonal injury, regeneration and transport

  Anne M. Taylor;Mathew Blurton-Jones;Seog Woo Rhee;David H. Cribbs

  1328
  Citations

• iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases

  Edsel M. Abud;Ricardo N. Ramirez;Eric S. Martinez;Luke M. Healy

  1150
  Citations

• Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease.

  Mathew Blurton-Jones;Masashi Kitazawa;Hilda Martinez-Coria;Nicholas A. Castello

  1034
  Citations

• Eliminating microglia in Alzheimer’s mice prevents neuronal loss without modulating amyloid-β pathology

  Elizabeth E. Spangenberg;Rafael J. Lee;Allison R. Najafi;Rachel A. Rice

  748
  Citations

• Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology

  Robert A. Rissman;Wayne W. Poon;Mathew Blurton-Jones;Salvatore Oddo

  656
  Citations

• Synergistic Interactions between Abeta, tau, and alpha-synuclein: acceleration of neuropathology and cognitive decline.

  Lani K. Clinton;Mathew Blurton-Jones;Kristoffer Myczek;John Q. Trojanowski

  639
  Citations

• Aβ inhibits the proteasome and enhances amyloid and tau accumulation

  Bertrand P. Tseng;Kim N. Green;Julie L. Chan;Mathew Blurton-Jones

  457
  Citations

• Development and validation of a simplified method to generate human microglia from pluripotent stem cells

  Amanda McQuade;Morgan Coburn;Christina H. Tu;Jonathan Hasselmann

  447
  Citations

• The adaptive immune system restrains Alzheimer’s disease pathogenesis by modulating microglial function

  Samuel E. Marsh;Edsel M. Abud;Anita Lakatos;Alborz Karimzadeh

  428
  Citations

• Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations

  Rocío Rojo;Rocío Rojo;Anna Raper;Derya D. Ozdemir;Lucas Lefevre

  366
  Citations

• Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo.

  Jonathan Hasselmann;Morgan A. Coburn;Whitney England;Dario X. Figueroa Velez

  365
  Citations

• Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease.

  Amanda McQuade;You Jung Kang;Jonathan Hasselmann;Amit Jairaman

  333
  Citations

• Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology

  Fiona E. McAlpine;Jae Kyung Lee;Ashley S. Harms;Kelly A. Ruhn

  327
  Citations

• Pathways by which Abeta facilitates tau pathology.

  Mathew Blurton-Jones;Frank M Laferla

  262
  Citations

• Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal loss

  Rahasson R. Ager;Joy L. Davis;Andy Agazaryan;Francisca Benavente

  253
  Citations

• Inflammatory changes parallel the early stages of Alzheimer disease

  A. Parachikova;M.G. Agadjanyan;D.H. Cribbs;M. Blurton-Jones

  252
  Citations

• The role of caspase cleavage of tau in Alzheimer disease neuropathology.

  Carl W. Cotman;Wayne W. Poon;Robert A. Rissman;Mathew Blurton-Jones

  250
  Citations

• β-Amyloid impairs axonal BDNF retrograde trafficking.

  Wayne W. Poon;Mathew Blurton-Jones;Christina H. Tu;Leila M. Feinberg

  243
  Citations

• Microglia in Alzheimer's Disease: Exploring How Genetics and Phenotype Influence Risk.

  Amanda McQuade;Mathew Blurton-Jones

  223
  Citations

• Neural Stem Cells Improve Memory in an Inducible Mouse Model of Neuronal Loss

  Tritia R. Yamasaki;Mathew Blurton-Jones;Debbi A. Morrissette;Masashi Kitazawa

  216
  Citations

• Neural stem cell therapy for neurodegenerative disorders: The role of neurotrophic support.

  Samuel E. Marsh;Mathew Blurton-Jones

  170
  Citations