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Immunology

D-Index
86
Citations
22542
World Ranking
1285
National Ranking
666

Overview

Andrea J. Tenner is affiliated with the University of California, Irvine in the United States. Their research spans the fields of Medicine and Neuroscience, with particular focus on Neurology, Physiology, Molecular Biology, Immunology, and Biological Psychiatry as subfields.

The primary topics of their work include:

  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Complement system in diseases
  • Tryptophan and brain disorders
  • Neurological Disease Mechanisms and Treatments
  • Neuroscience and Neuropharmacology Research
  • Bioinformatics and Genomic Networks

Andrea J. Tenner's recent significant publications include:

  • Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer's disease, 2021, Scientific Data
  • The good, the bad, and the opportunities of the complement system in neurodegenerative disease, 2020, Journal of Neuroinflammation
  • Neuroinflammation in Alzheimer disease, 2024, Nature reviews. Immunology
  • Therapeutic Targeting of the Complement System: From Rare Diseases to Pandemics, 2021, Pharmacological Reviews
  • Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease, 2022, Frontiers in Neuroscience

They have frequently published in venues such as:

  • Alzheimer s & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Neuroinflammation
  • Immunobiology
  • Alzheimer s & Dementia Translational Research & Clinical Interventions

Andrea J. Tenner collaborates regularly with several co-authors, notably:

  • Frank M. LaFerla (27 publications)
  • Grant R. MacGregor (26 publications)
  • Kim N. Green (26 publications)
  • Ángela Gómez-Arboledas (25 publications)
  • Shimako Kawauchi (22 publications)

Best Publications

  • Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages

    Takafumi Yokota;Kenji Oritani;Isao Takahashi;Jun Ishikawa

  • The role of the anaphylatoxins in health and disease.

    Andreas Klos;Andrea J. Tenner;Kay-Ole Johswich;Rahasson R. Ager

  • Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study

    David H Cribbs;Nicole C Berchtold;Victoria Perreau;Paul D Coleman

  • Complement in the Brain

    Robert Veerhuis;Henrietta M. Nielsen;Andrea J. Tenner

  • beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the C1q A chain

    Haixiang Jiang;D. Burdick;C. G. Glabe;C. W. Cotman

  • A dramatic increase of C1q protein in the CNS during normal aging.

    Alexander H. Stephan;Daniel V. Madison;José María Mateos;Deborah A. Fraser

  • Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer's disease.

    Stefania Forner;Shimako Kawauchi;Gabriela Balderrama-Gutierrez;Enikö A. Kramár

  • Absence of C1q Leads to Less Neuropathology in Transgenic Mouse Models of Alzheimer's Disease

    Maria Isabel Fonseca;Jun Zhou;Marina Botto;Andrea J. Tenner

  • Human pulmonary surfactant protein (SP-A), a protein structurally homologous to C1q, can enhance FcR- and CR1-mediated phagocytosis.

    A J Tenner;S L Robinson;J Borchelt;J R Wright

  • Neuronal protection in stroke by an sLex-glycosylated complement inhibitory protein.

    Judy Huang;Louis J. Kim;Richard Mealey;Henry C. Marsh

  • Molecular and Cellular Characterization of the Membrane Attack Complex, C5b-9, in Alzheimer’s Disease

    S Webster;L.-F Lue;L Brachova;A.J Tenner

  • Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease.

    Yasuji Matsuoka;Melanie Picciano;Brian Malester;John LaFrancois

  • Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain

    Maria I. Fonseca;Shu-Hui Chu;Michael X. Hernandez;Melody J. Fang

  • Purification and radiolabeling of human C1q.

    A J Tenner;P H Lesavre;N R Cooper

  • cDNA Cloning and Primary Structure Analysis of C1qRP, the Human C1q/MBL/SPA Receptor That Mediates Enhanced Phagocytosis In Vitro

    Ronald R. Nepomuceno;Agnes H. Henschen-Edman;Wilson H. Burgess;Andrea J. Tenner

  • Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer’s disease

    Unknown

  • Elimination of Microglia Improves Functional Outcomes Following Extensive Neuronal Loss in the Hippocampus.

    Rachel A. Rice;Elizabeth E. Spangenberg;Hana Yamate-Morgan;Rafael J. Lee

  • Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease.

    Maria I. Fonseca;Rahasson R. Ager;Shu Hui Chu;Ozkan Yazan

  • Complement Protein C1q Directs Macrophage Polarization and Limits Inflammasome Activity during the Uptake of Apoptotic Cells

    Marie E. Benoit;Elizabeth V. Clarke;Pedro Morgado;Deborah A. Fraser

  • Localization and Cell Association of C1q in Alzheimer's Disease Brain

    Arman Afagh;Brian J. Cummings;David H. Cribbs;Carl W. Cotman

  • C1qRp defines a new human stem cell population with hematopoietic and hepatic potential

    Guénahel H. Danet;Jennifer L. Luongo;Gary Butler;Min Min Lu

  • Novel Aβ peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease

    Jun Zhou;María I Fonseca;Rakez Kayed;Irma Arias Hernández

Frequent Co-Authors

David H. Cribbs
David H. Cribbs University of California, Irvine
Carl W. Cotman
Carl W. Cotman University of California, Irvine
Frank M. LaFerla
Frank M. LaFerla University of California, Irvine
Kim N. Green
Kim N. Green University of California, Irvine
Charles G. Glabe
Charles G. Glabe University of California, Irvine
Trent M. Woodruff
Trent M. Woodruff University of Queensland
Marcelo A. Wood
Marcelo A. Wood University of California, Irvine
Neil R. Cooper
Neil R. Cooper Scripps Research Institute
Michael M. Frank
Michael M. Frank Duke University
Elizabeth Head
Elizabeth Head University of California, Irvine

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