2026 Markus Huber-Lang: Immunology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Immunology	81	1559	1418	108	98	398	24912

Overview

Markus Huber-Lang is affiliated with the University of Ulm in Germany and has an extensive publication record in the fields of medicine and immunology. Their work primarily focuses on the complement system's role in disease processes, immune response mechanisms, and trauma-related pathophysiology.

Their published research spans various topics including:

Complement system in diseases
Immune response and inflammation
Sepsis diagnosis and treatment
Neutrophil, myeloperoxidase, and oxidative mechanisms
COVID-19 clinical research studies
Trauma and emergency care studies
Traumatic brain injury and neurovascular disturbances

Among recent notable papers involving or related to their research area are:

Complement as a target in COVID-19? (2020, Nature Reviews Immunology)
The first case of COVID-19 treated with the complement C3 inhibitor AMY-101 (2020, Clinical Immunology)
Complement C3 vs C5 inhibition in severe COVID-19: Early clinical findings reveal differential biological efficacy (2020, Clinical Immunology)
Immunopathophysiology of trauma-related acute kidney injury (2020, Nature Reviews Nephrology)
Interleukin 8 Elicits Rapid Physiological Changes in Neutrophils That Are Altered by Inflammatory Conditions (2021, Journal of Innate Immunity)

The frequent co-authors working alongside Markus Huber-Lang include:

Rebecca Halbgebauer
Marco Mannes
Bo Nilsson
David Alexander Christian Messerer
Annette Palmer

Their research outputs have been published in various scientific venues, notably:

Frontiers in Immunology
bioRxiv (Cold Spring Harbor Laboratory)
Immunobiology
Shock
International Journal of Molecular Sciences

Markus Huber-Lang has also contributed to book publications, with a title addressing clinical course and organ cross talk in critical illness released by Frontiers Media in 2023.

Within their academic disciplines, their work is concentrated in the subfields of immunology, molecular biology, epidemiology, neurology, and surgery, further demonstrating a multidisciplinary approach.

Best Publications

Immunodesign of experimental sepsis by cecal ligation and puncture.

Daniel Rittirsch;Markus S Huber-Lang;Michael A Flierl;Peter A Ward

2414
Citations
Generation of C5a in the absence of C3: a new complement activation pathway.

Markus Huber-Lang;J Vidya Sarma;Firas S Zetoune;Daniel Rittirsch

1197
Citations
Molecular Intercommunication between the Complement and Coagulation Systems

Umme Amara;Michael A. Flierl;Daniel Rittirsch;Andreas Klos

815
Citations
Innate immune responses to trauma

Markus Huber-Lang;John D. Lambris;Peter A. Ward

604
Citations
Phagocyte-derived catecholamines enhance acute inflammatory injury

Michael A. Flierl;Daniel Rittirsch;Brian A. Nadeau;Anthony J. Chen

535
Citations
Complement as a target in COVID-19?

Antonio M. Risitano;Dimitrios C. Mastellos;Markus Huber-Lang;Despina Yancopoulou

496
Citations
Protective effects of C5a blockade in sepsis

Boris J. Czermak;Vidya Sarma;Carl L. Pierson;Roscoe L. Warner

496
Citations
Functional roles for C5a receptors in sepsis

Daniel Rittirsch;Michael A Flierl;Brian A Nadeau;Danielle E Day

463
Citations
Role of C5a in Multiorgan Failure During Sepsis

Markus Huber-Lang;Vidya J. Sarma;Kristina T. Lu;Stephanie R. McGuire

351
Citations
Generation of C5a by phagocytic cells.

Markus Huber-Lang;Ellen M. Younkin;J. Vidya Sarma;Niels Riedemann

298
Citations
New Insights of an Old Defense System: Structure, Function, and Clinical Relevance of the Complement System

Christian Ehrnthaller;Anita Ignatius;Florian Gebhard;Markus Huber-Lang

293
Citations
The first case of COVID-19 treated with the complement C3 inhibitor AMY-101.

Sara Mastaglio;Annalisa Ruggeri;Antonio M. Risitano;Piera Angelillo

289
Citations
Complement-induced impairment of innate immunity during sepsis.

Markus S. Huber-Lang;Ellen M. Younkin;J. Vidya Sarma;Stephanie R. McGuire

289
Citations
Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS) : an international expert consensus initiative for improvement of animal modeling in sepsis

Marcin F. Osuchowski;Alfred Ayala;Soheyl Bahrami;Michael Bauer

248
Citations
Adverse functions of IL-17A in experimental sepsis

Michael A. Flierl;Daniel Rittirsch;Hongwei Gao;Laszlo M. Hoesel

242
Citations
Complement C3 vs C5 inhibition in severe COVID-19: Early clinical findings reveal differential biological efficacy.

Dimitrios C. Mastellos;Bruno G.P. Pires da Silva;Benedito A.L. Fonseca;Natasha P. Fonseca

242
Citations
Catecholamines-crafty weapons in the inflammatory arsenal of immune/inflammatory cells or opening pandora's box?

Michael A. Flierl;Daniel Rittirsch;Markus Huber-Lang;J. Vidya Sarma

241
Citations
Complement C3a and C5a modulate osteoclast formation and inflammatory response of osteoblasts in synergism with IL-1β.

Anita Ignatius;Philipp Schoengraf;Ludwika Kreja;Astrid Liedert

223
Citations
Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

Marcin F. Osuchowski;Alfred Ayala;Soheyl Bahrami;Michael Bauer

222
Citations
Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites

David Braig;David Braig;Tracy L. Nero;Hans Georg Koch;Benedict Kaiser

217
Citations
Anti-C5a Ameliorates Coagulation/Fibrinolytic Protein Changes in a Rat Model of Sepsis

Ines J. Laudes;Jeffrey C. Chu;Sujata Sikranth;Markus Huber-Lang

213
Citations
Protection of innate immunity by C5aR antagonist in septic mice

Markus S. Huber-Lang;Niels C. Riedeman;J. Vidya Sarma;Ellen M. Younkin

207
Citations
Expression and function of C5a receptor in mouse microvascular endothelial cells.

Ines J. Laudes;Jeffrey C. Chu;Markus Huber-Lang;Ren Feng Guo

204
Citations

Frequent Co-Authors

Peter A. Ward University of Michigan–Ann Arbor

John D. Lambris University of Pennsylvania

J. Vidya Sarma University of Michigan–Ann Arbor

Hubert Schrezenmeier University of Ulm

Bo Nilsson Uppsala University

Jörg Köhl University of Lübeck

Kristina Nilsson Ekdahl Uppsala University

Tom Eirik Mollnes Oslo University Hospital

Michael K. Georgieff University of Minnesota

Lutz Claes University of Ulm

External Links

Personal website of Markus Huber-Lang

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