D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 55 Citations 6,946 206 World Ranking 2890 National Ranking 1362

Research.com Recognitions

Awards & Achievements

2015 - Fellow, National Academy of Inventors

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Immune system

Stephen Tomlinson mainly investigates Complement system, Immunology, Complement membrane attack complex, Biochemistry and Alternative complement pathway. Complement system and Inflammation are commonly linked in his work. Stephen Tomlinson has researched Immunology in several fields, including Reperfusion injury and Receptor.

His studies examine the connections between Complement membrane attack complex and genetics, as well as such issues in CD59, with regards to Binding site and Monoclonal antibody therapy. In general Biochemistry, his work in Sialic acid, Trypanosoma brucei and Glycoprotein is often linked to Trypanosoma cruzi linking many areas of study. The various areas that Stephen Tomlinson examines in his Alternative complement pathway study include Complement factor B and Classical complement pathway.

His most cited work include:

  • Complement function in mAb-mediated cancer immunotherapy (234 citations)
  • A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration. (158 citations)
  • Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection. (148 citations)

What are the main themes of his work throughout his whole career to date?

Complement system, Immunology, Alternative complement pathway, Complement inhibitor and Inflammation are his primary areas of study. Stephen Tomlinson combines subjects such as Cancer research, Pharmacology and Cell biology with his study of Complement system. His study explores the link between Immunology and topics such as Reperfusion injury that cross with problems in Liver regeneration.

His research investigates the connection between Alternative complement pathway and topics such as Factor H that intersect with issues in CD46. His Complement inhibitor research includes themes of Decay-accelerating factor and Spinal cord injury, Spinal cord. Stephen Tomlinson works mostly in the field of Inflammation, limiting it down to concerns involving Stroke and, occasionally, Neuroinflammation.

He most often published in these fields:

  • Complement system (61.94%)
  • Immunology (55.71%)
  • Alternative complement pathway (26.30%)

What were the highlights of his more recent work (between 2015-2021)?

  • Complement system (61.94%)
  • Immunology (55.71%)
  • Inflammation (23.88%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Complement system, Immunology, Inflammation, Neuroinflammation and Complement inhibitor. Alternative complement pathway is the focus of his Complement system research. His Alternative complement pathway study integrates concerns from other disciplines, such as Haematopoiesis, Complement receptor 2, Factor H and Pharmacology.

His Immunology study frequently draws parallels with other fields, such as Spinal cord injury. His Neuroinflammation research is multidisciplinary, relying on both Stroke and Cognitive decline. His work carried out in the field of Complement inhibitor brings together such families of science as Vascularized Composite Allografts, Perfusion, Reperfusion injury, Opsonin and Monoclonal antibody.

Between 2015 and 2021, his most popular works were:

  • Identifying the Role of Complement in Triggering Neuroinflammation after Traumatic Brain Injury. (57 citations)
  • Aberrant JMJD3 Expression Upregulates Slug to Promote Migration, Invasion, and Stem Cell–Like Behaviors in Hepatocellular Carcinoma (46 citations)
  • Targeted complement inhibition salvages stressed neurons and inhibits neuroinflammation after stroke in mice. (45 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

Complement system, Immunology, Inflammation, Stroke and Alternative complement pathway are his primary areas of study. His Complement system research includes elements of Cancer research, Pathogenesis, Retina, Cell biology and Innate immune system. His study in Immunology is interdisciplinary in nature, drawing from both Reperfusion injury and Cell.

His study looks at the relationship between Inflammation and fields such as Complement, as well as how they intersect with chemical problems. His Stroke research is multidisciplinary, incorporating elements of Neuroimaging, Lesion, Surgery and Cortex. Stephen Tomlinson works mostly in the field of Alternative complement pathway, limiting it down to topics relating to Macular degeneration and, in certain cases, Gene delivery, Retinal pigment epithelium, Factor H and Complement receptor 2, as a part of the same area of interest.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Complement function in mAb-mediated cancer immunotherapy

Kyra A. Gelderman;Stephen Tomlinson;Gordon D. Ross;Arko Gorter.
Trends in Immunology (2004)

338 Citations

Characterization of a Novel Trypanosome Lytic Factor from Human Serum

Jayne Raper;Ramie Fung;Jorge Ghiso;Victor Nussenzweig.
Infection and Immunity (1999)

196 Citations

Oxidative stress renders retinal pigment epithelial cells susceptible to complement-mediated injury.

Joshua M. Thurman;Brandon Renner;Kannan Kunchithapautham;Viviana P. Ferreira.
Journal of Biological Chemistry (2009)

195 Citations

A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration.

Ba¨rbel Rohrer;Qin Long;Beth Coughlin;R. Brooks Wilson.
Investigative Ophthalmology & Visual Science (2009)

189 Citations

Complement defense mechanisms

Stephen Tomlinson.
Current Opinion in Immunology (1993)

188 Citations

Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection.

Carl Atkinson;Hongbin Song;Bo Lu;Fei Qiao.
Journal of Clinical Investigation (2005)

182 Citations

Complement-Mediated Mechanisms in Anti-GD2 Monoclonal Antibody Therapy of Murine Metastatic Cancer

Masaki Imai;Charles Landen;Rieko Ohta;Nai-Kong V. Cheung.
Cancer Research (2005)

176 Citations

Substrate specificity of the Trypanosoma cruzi trans-sialidase

Filip Vandekerckhove;Sergio Schenkman;Lain Pontes de Carvalho;Stephen Tomlinson.
Glycobiology (1992)

169 Citations

Complement-independent, peroxide-induced antibody lysis of platelets in HIV-1-related immune thrombocytopenia.

Michael Nardi;Stephen Tomlinson;M.Alba Greco;Simon Karpatkin.
Cell (2001)

169 Citations

The induction of Trypanosoma cruzi trypomastigote to amastigote transformation by low pH.

S. Tomlinson;F. Vandekerckhove;U. Frevert;V. Nussenzweig.
Parasitology (1995)

140 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Stephen Tomlinson

V. Michael Holers

V. Michael Holers

University of Colorado Denver

Publications: 54

John D. Lambris

John D. Lambris

University of Pennsylvania

Publications: 45

Zihai Li

Zihai Li

The Ohio State University

Publications: 28

Stephen L. Hajduk

Stephen L. Hajduk

University of Georgia

Publications: 24

B. Paul Morgan

B. Paul Morgan

Cardiff University

Publications: 24

Claire L. Harris

Claire L. Harris

Newcastle University

Publications: 23

Etienne Pays

Etienne Pays

Université Libre de Bruxelles

Publications: 22

Mohamed R. Daha

Mohamed R. Daha

University Medical Center Groningen

Publications: 22

Alberto C.C. Frasch

Alberto C.C. Frasch

National University of General San Martín

Publications: 20

Sergio Schenkman

Sergio Schenkman

Federal University of Sao Paulo

Publications: 19

Michael Kirschfink

Michael Kirschfink

Heidelberg University

Publications: 18

Jane E. Salmon

Jane E. Salmon

Hospital for Special Surgery

Publications: 17

Sébastien Lacroix-Desmazes

Sébastien Lacroix-Desmazes

Sorbonne University

Publications: 17

Michael A. J. Ferguson

Michael A. J. Ferguson

University of Dundee

Publications: 17

Lubka T. Roumenina

Lubka T. Roumenina

Université Paris Cité

Publications: 16

Steven H. Sacks

Steven H. Sacks

King's College London

Publications: 16

Trending Scientists

Nicolò Cesa-Bianchi

Nicolò Cesa-Bianchi

University of Milan

Tamás Insperger

Tamás Insperger

Budapest University of Technology and Economics

Keitaro Yoshihara

Keitaro Yoshihara

Tokyo Metropolitan University

Denis Rodrigue

Denis Rodrigue

Université Laval

Stan Veprek

Stan Veprek

Technical University of Munich

Jeffrey D. Esko

Jeffrey D. Esko

University of California, San Diego

Douglas A. Gage

Douglas A. Gage

Michigan State University

Volker Brinkmann

Volker Brinkmann

Max Planck Society

Paula J. Fedorka-Cray

Paula J. Fedorka-Cray

North Carolina State University

Ray Johnson

Ray Johnson

Queens College, CUNY

István Czigler

István Czigler

Hungarian Academy of Sciences

Kate M. Bennett

Kate M. Bennett

University of Liverpool

David T.W. Wong

David T.W. Wong

University of California, Los Angeles

Barbara J. Burns

Barbara J. Burns

Duke University

Fabrizio Veglia

Fabrizio Veglia

University of Milan

Markus J. Aschwanden

Markus J. Aschwanden

Advanced Technology Center

Something went wrong. Please try again later.