World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
9971
World Ranking
14556
National Ranking
6108

Overview

Barry W. Festoff is affiliated with the University of Kansas in the United States. Their research spans multiple fields, primarily focusing on Medicine and Biochemistry, Genetics and Molecular Biology. Within these areas, their work addresses several subfields including Hematology, Molecular Biology, and Psychiatry and Mental Health.

Their published research covers topics related to blood coagulation and thrombosis mechanisms, signaling pathways in disease, and cerebral palsy and movement disorders. These topics reflect an interdisciplinary approach combining molecular and clinical perspectives.

Among their recent scholarly contributions is the paper titled The Evolving Concept of Neuro-Thromboinflammation for Neurodegenerative Disorders and Neurotrauma: A Rationale for PAR1-Targeting Therapies, published in 2021 in the journal Biomolecules. This publication has been cited by peers, indicating ongoing engagement with emerging concepts in neuroinflammation and therapeutic strategies.

  • The Evolving Concept of Neuro-Thromboinflammation for Neurodegenerative Disorders and Neurotrauma: A Rationale for PAR1-Targeting Therapies (2021, Biomolecules)

Collaboration is evident in their research activities, with Chris Dockendorff identified as a frequent coauthor. The concentration of publications in venues such as Biomolecules highlights their connection to molecular and biochemical research communities.

  • Chris Dockendorff

  • Biomolecules

Barry W. Festoff's work integrates clinical and molecular dimensions, particularly in understanding mechanisms related to blood coagulation and neuroinflammation. The research aims to explore signaling pathways pertinent to disease processes, contributing to broader knowledge in neurodegenerative disorders and movement-related conditions like cerebral palsy.

Best Publications

  • Xeroderma pigmentosum. An inherited diseases with sun sensitivity, multiple cutaneous neoplasms, and abnormal DNA repair.

    Jay H. Robbins;Kenneth H. Kraemer;Marvin A. Lutzner;Barry W. Festoff

  • Effect of recombinant human insulin-like growth factor-I on progression of ALS A placebo-controlled study

    Eugene C. Lai;K. J. Felice;B. W. Festoff;M. J. Gawel

  • Apoptosis in Cellular Compartments of Rat Spinal Cord After Severe Contusion Injury

    Chi Yong;Paul M. Arnold;Paul M. Arnold;Mikhail N. Zoubine;Mikhail N. Zoubine;Bruce A. Citron;Bruce A. Citron

  • Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease expression early after spinal cord injury.

    Barry W. Festoff;Syed Ameenuddin;Paul M. Arnold;Paul M. Arnold;Andrea Wong

  • Participation of protease‐activated receptor‐1 in thrombin‐induced microglial activation

    Zhiming Suo;Min Wu;Syed Ameenuddin;Heidi E. Anderson

  • Microglial activation, increased TNF and SERT expression in the prefrontal cortex define stress-altered behaviour in mice susceptible to anhedonia

    Yvonne Couch;Daniel C. Anthony;Oleg Dolgov;Alexander Revischin

  • HMGB1 and thrombin mediate the blood-brain barrier dysfunction acting as biomarkers of neuroinflammation and progression to neurodegeneration in Alzheimer’s disease

    Barry W. Festoff;Ravi K. Sajja;Patrick van Dreden;Luca Cucullo

  • PROTEOLYTIC ACTION OF THROMBIN IS REQUIRED FOR ELECTRICAL ACTIVITY-DEPENDENT SYNAPSE REDUCTION

    Yuan Liu;R. D. Fields;B. W. Festoff;P. G. Nelson

  • Protein crosslinking, tissue transglutaminase, alternative splicing and neurodegeneration.

    Bruce A Citron;Zhiming Suo;Zhiming Suo;Karen SantaCruz;Peter J.A Davies

  • Rapid upregulation of caspase-3 in rat spinal cord after injury: mRNA, protein, and cellular localization correlates with apoptotic cell death.

    Bruce A. Citron;Paul M. Arnold;Paul M. Arnold;Cyril Sebastian;Cyril Sebastian;Fan Qin

  • Thrombin perturbs neurite outgrowth and induces apoptotic cell death in enriched chick spinal motoneuron cultures through caspase activation.

    Victoria L. Turgeon;Elizabeth D. Lloyd;Siwei Wang;Barry W. Festoff

  • Treatment of Ventricular Arrhythmia by Permanent Atrial Pacemaker and Cardiac Sympathectomy

    Douglas P. Zipes;Barry Festoff;Stephen F. Schaal;Clyde Cox

  • Biochemical studies of synapses in vitro. 3. Ionic activation of protein synthesis.

    Stanley H. Appel;Lucila Autilio;Barry W. Festoff;Antonio V. Escueta

  • Thrombin is an extracellular signal that activates intracellular death protease pathways inducing apoptosis in model motor neurons

    Irina V. Smirnova;Sherri X. Zhang;Sherri X. Zhang;Bruce A. Citron;Bruce A. Citron;Paul M. Arnold;Paul M. Arnold

  • Effect of diphenylhydantoin on synaptosome sodium-potassium-ATPase

    Barry W. Festoff;Stanley H. Appel

  • Intron-exon swapping of transglutaminase mRNA and neuronal Tau aggregation in Alzheimer's disease.

    Bruce A. Citron;Karen S. SantaCruz;Peter J.A. Davies;Barry W. Festoff

  • Persistent Protease-activated Receptor 4 Signaling Mediates Thrombin-induced Microglial Activation *

    Zhiming Suo;Zhiming Suo;Min Wu;Bruce A. Citron;Bruce A. Citron;Chenhua Gao

  • Insulin resistance in amyotrophic lateral sclerosis

    Erlinda T. Reyes;Erlinda T. Reyes;Osvaldo H. Perurena;Osvaldo H. Perurena;Barry W. Festoff;Barry W. Festoff;Rachel Jorgensen

  • Rapid tau aggregation and delayed hippocampal neuronal death induced by persistent thrombin signaling

    Zhiming Suo;Zhiming Suo;Min Wu;Bruce A. Citron;Bruce A. Citron;Robert E. Palazzo

  • Neurotrophic control of 16S acetylcholinesterase at the vertebrate neuromuscular junction

    Hugo L. Fernandez;Hugo L. Fernandez;Myron J. Duell;Myron J. Duell;Barry W. Festoff;Barry W. Festoff

Frequent Co-Authors

Stanley H. Appel
Stanley H. Appel Houston Methodist
Daniel C. Anthony
Daniel C. Anthony University of Oxford
Phillip G. Nelson
Phillip G. Nelson National Institutes of Health
Peter J. A. Davies
Peter J. A. Davies Texas A&M University
Tatyana Strekalova
Tatyana Strekalova Maastricht University
Harry W.M. Steinbusch
Harry W.M. Steinbusch Maastricht University
Douglas E. Brenneman
Douglas E. Brenneman Kannalife Sciences
Russell H. Swerdlow
Russell H. Swerdlow University of Kansas
Claudine Soria
Claudine Soria University of Rouen
Nancy E.J. Berman
Nancy E.J. Berman University of Kansas

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