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Molecular Biology

D-Index
76
Citations
22750
World Ranking
1147
National Ranking
595

Overview

Kenneth H. Kraemer is affiliated with the National Institutes of Health in the United States. The primary focus of their research is on molecular biology and genetics with an emphasis on mechanisms related to DNA repair and genetic diseases.

Their publication record reflects contributions in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Subfields of particular focus include Molecular Biology, Genetics, Epidemiology, Cell Biology, and Pathology and Forensic Medicine.

The main research topics covered by Kenneth H. Kraemer include:

  • DNA Repair Mechanisms
  • RNA regulation and disease
  • Genetic factors in colorectal cancer
  • Mitochondrial Function and Pathology
  • Genetic Neurodegenerative Diseases
  • Hair Growth and Disorders
  • Porphyrin Metabolism and Disorders

Frequent co-authors in their work include:

  • John J. DiGiovanna
  • Deborah Tamura
  • Sikandar G. Khan
  • S.G. Khan
  • Jack Jeskey

Kraemer has published extensively in the following venues:

  • Journal of Investigative Dermatology
  • British Journal of Dermatology
  • Journal of Endocrinological Investigation
  • American Journal of Medical Genetics Part A
  • Frontiers in Oncology

Selected recent papers include:

  • "Xeroderma Pigmentosum: A Model for Human Premature Aging," 2021, Journal of Investigative Dermatology
  • "Xeroderma Pigmentosum Group C Splice Mutation Associated with Autism and Hypoglycinemia," 2021, UNC Libraries
  • "Thyroid nodules in xeroderma pigmentosum patients: a feature of premature aging," 2020, Journal of Endocrinological Investigation
  • "Debilitating hip degeneration in trichothiodystrophy: Association with ERCC2/XPD mutations, osteosclerosis, osteopenia, coxa valga, contractures, and osteonecrosis," 2022, American Journal of Medical Genetics Part A
  • "Retrospective study of efficacy and adverse events of immune checkpoint inhibitors in 22 xeroderma pigmentosum patients with metastatic or unresectable cancers," 2023, Frontiers in Oncology

Best Publications

  • Xeroderma Pigmentosum: Cutaneous, Ocular, and Neurologic Abnormalities in 830 Published Cases

    Kenneth H. Kraemer;Myung M. Lee;Joseph Scotto

  • Xeroderma pigmentosum. An inherited diseases with sun sensitivity, multiple cutaneous neoplasms, and abnormal DNA repair.

    Jay H. Robbins;Kenneth H. Kraemer;Marvin A. Lutzner;Barry W. Festoff

  • Prevention of skin cancer in xeroderma pigmentosum with the use of oral isotretinoin

    Kenneth H. Kraemer;John J. DiGiovanna;Alan N. Moshell;Robert E. Tarone

  • The role of sunlight and DNA repair in melanoma and nonmelanoma skin cancer. The xeroderma pigmentosum paradigm.

    Kenneth H. Kraemer;Myung Moo Lee;Alan D. Andrews;W. Clark Lambert

  • Diagnosis and Treatment of Early Melanoma: NIH Consensus Development Panel on Early Melanoma

    Lowell A. Goldsmith;Frederic B. Askin;Alfred E. Chang;Cynthia Cohen

  • Shining a light on xeroderma pigmentosum.

    John J. DiGiovanna;Kenneth H. Kraemer

  • DNA polymerase η is an A-T mutator in somatic hypermutation of immunoglobulin variable genes

    Xianmin Zeng;David B. Winter;Cynthia Kasmer;Kenneth H. Kraemer

  • High Risk of Malignant Melanoma in Melanoma-Prone Families with Dysplastic Nevi

    Mark H. Greene;Wallace H. Clark;Margaret A. Tucker;Kenneth H. Kraemer

  • Sunlight and skin cancer: Another link revealed

    Kenneth H. Kraemer

  • Cancer and neurologic degeneration in xeroderma pigmentosum: long term follow-up characterises the role of DNA repair

    Porcia T Bradford;Alisa M Goldstein;Deborah Tamura;Sikandar G Khan

  • DNA repair protects against cutaneous and internal neoplasia: evidence from xeroderma pigmentosum

    Kenneth H. Kraemer;Myung M. Lee;Joseph Scotto

  • Xeroderma pigmentosum, trichothiodystrophy and Cockayne syndrome: a complex genotype-phenotype relationship.

    Kenneth H. Kraemer;Nicholas J. Patronas;Raphael Schiffmann;Brian P. Brooks

  • Transcription-coupled Nucleotide Excision Repair as a Determinant of Cisplatin Sensitivity of Human Cells

    Takahisa Furuta;Takahiro Ueda;Gregory Aune;Alain Sarasin

  • Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair.

    Yuji Takebayashi;Philippe Pourquier;Drazen B. Zimonjic;Kentaro Nakayama

  • Acquired precursors of cutaneous malignant melanoma. The familial dysplastic nevus syndrome.

    Mark H. Greene;Wallace H. Clark;Margaret A. Tucker;David E. Elder

  • Cockayne syndrome and xeroderma pigmentosum DNA repair disorders with overlaps and paradoxes

    Isabelle Rapin;Y. Lindenbaum;Y. Lindenbaum;D. W. Dickson;K. H. Kraemer

  • Trichothiodystrophy: a systematic review of 112 published cases characterises a wide spectrum of clinical manifestations

    Salma Faghri;Deborah Tamura;Kenneth H. Kraemer;John J. DiGiovanna

  • Photoproduct frequency is not the major determinant of UV base substitution hot spots or cold spots in human cells

    Douglas E. Brash;Saraswathy Seetharam;Kenneth H. Kraemer;Michael M. Seidman

  • Restricted ultraviolet mutational spectrum in a shuttle vector propagated in xeroderma pigmentosum cells

    Anders Bredberg;Kenneth H. Kraemer;Michael M. Seidman

  • Xeroderma pigmentosum and the role of UV-induced DNA damage in skin cancer.

    Harry van Steeg;Kenneth H Kraemer

Frequent Co-Authors

Michael M. Seidman
Michael M. Seidman National Institutes of Health
Robert E. Tarone
Robert E. Tarone Vanderbilt University Medical Center
Margaret A. Tucker
Margaret A. Tucker National Institutes of Health
Alisa M. Goldstein
Alisa M. Goldstein National Institutes of Health
Mark H. Greene
Mark H. Greene National Institutes of Health
Vilhelm A. Bohr
Vilhelm A. Bohr University of Copenhagen
Douglas E. Brash
Douglas E. Brash Yale University
David E. Elder
David E. Elder Hospital of the University of Pennsylvania
Thomas Schneider
Thomas Schneider National Institutes of Health
Alan R. Lehmann
Alan R. Lehmann University of Sussex

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