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Douglas E. Brash

Douglas E. Brash

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
19778
World Ranking
14764
National Ranking
6172

Overview

Douglas E. Brash is affiliated with Yale University in the United States. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a focused contribution in Molecular Biology, Genetics, Health, Toxicology and Mutagenesis, Cell Biology, and Cellular and Molecular Neuroscience.

The scientist's work encompasses a range of topics, including:

  • bioluminescence and chemiluminescence research
  • Retinal Development and Disorders
  • melanin and skin pigmentation
  • Photoreceptor and optogenetics research
  • Olfactory and Sensory Function Studies
  • Philosophy and History of Science
  • Origins and Evolution of Life

Their frequent publication venues reflect this interdisciplinary scope and include:

  • Mutation Research/Reviews in Mutation Research
  • Proceedings of the National Academy of Sciences
  • Photochemistry and Photobiology
  • Cancers
  • Antioxidants

Recent research contributions by Douglas E. Brash include the following papers:

  • "Slip versus Slop: A Head-to-Head Comparison of UV-Protective Clothing to Sunscreen," 2022, published in Cancers
  • "Next-generation sequencing methodologies to detect low-frequency mutations: "Catch me if you can"," 2023, published in Mutation Research/Reviews in Mutation Research
  • "Triplet-Energy Quenching Functions of Antioxidant Molecules," 2022, published in Antioxidants
  • "Chemiexcitation and melanin in photoreceptor disc turnover and prevention of macular degeneration," 2023, published in Proceedings of the National Academy of Sciences
  • "Chemiexcitation: Mammalian Photochemistry in the Dark†," 2023, published in Photochemistry and Photobiology

The scientist has collaborated on multiple projects with several frequent coauthors, including:

  • Letícia Christina Pires Gonçalves
  • Sanjay Premi
  • Meg A. Palmatier
  • Carlos Angelé-Martínez
  • Yanan Lyu

Best Publications

  • A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma.

    Douglas E. Brash;Jeffrey A. Rudolph;Jeffrey A. Simon;Anthony Lin

  • Sunburn and p53 in the onset of skin cancer

    Annemarie Ziegler;Alan S. Jonason;David J. Leffellt;Jeffrey A. Simon;Jeffrey A. Simon

  • Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.

    Michael Krauthammer;Yong Lin Kong;Byung Hak Ha;Perry Evans

  • Transformation of Human Bronchial Epithelial Cells by Infection with SV40 or Adenovirus-12 SV40 Hybrid Virus, or Transfection via Strontium Phosphate Coprecipitation with a Plasmid Containing SV40 Early Region Genes

    Roger R. Reddel;Yang Ke;Brenda I. Gerwin;Mary G. McMenamin

  • The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas.

    M R Gailani;M Ståhle-Bäckdahl;D J Leffell;M Glynn

  • Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers.

    Annemarie Ziegler;David J. Leffell;Subrahmanyam Kunala;Harsh W. Sharma

  • Frequent clones of p53-mutated keratinocytes in normal human skin

    Alan S. Jonason;Subrahmanyam Kunala;Gary J. Price;Richard J. Restifo

  • Sunlight and sunburn in human skin cancer: p53, apoptosis, and tumor promotion.

    Douglas E. Brash;Annemarie Ziegler;Alan S. Jonason;Jeffrey A. Simon

  • Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure

    Sanjay Premi;Silvia Wallisch;Camila M. Mano;Adam B. Weiner

  • UV-induced mutation hotspots occur at DNA damage hotspots

    Douglas E. Brash;William A. Haseltine

  • UV signature mutations.

    Douglas E. Brash

  • Sunlight and the onset of skin cancer

    Douglas E. Brash

  • Distribution of UV light-induced damage in a defined sequence of human DNA: detection of alkaline-sensitive lesions at pyrimidine nucleoside-cytidine sequences

    Judith A. Lippke;Lynn K. Gordon;Douglas E. Brash;William A. Haseltine

  • Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53.

    Douglas Grossman;Paul J. Kim;Olivier P. Blanc-Brude;Douglas E. Brash

  • Common contaminants in next-generation sequencing that hinder discovery of low-abundance microbes.

    Martin Laurence;Christos Hatzis;Douglas E. Brash

  • UV MUTAGENIC PHOTOPRODUCTS IN Escherichia coli AND HUMAN CELLS: A MOLECULAR GENETICS PERSPECTIVE ON HUMAN SKIN CANCER*

    Douglas E. Brash

  • Keratinocyte Apoptosis in Epidermal Development and Disease

    Deepak Raj;Douglas E. Brash;Douglas Grossman;Douglas Grossman

  • Photoproduct frequency is not the major determinant of UV base substitution hot spots or cold spots in human cells

    Douglas E. Brash;Saraswathy Seetharam;Kenneth H. Kraemer;Michael M. Seidman

  • Relationship Between Sunlight Exposure and a Key Genetic Alteration in Basal Cell Carcinoma

    Mae R. Gailani;David J. Leffell;AnneMarie Ziegler;Earl G. Gross

  • Ultraviolet Radiation Induced Signature Mutations in Photocarcinogenesis

    Norbert M. Wikonkal;Douglas E. Brash

Frequent Co-Authors

Kenneth H. Kraemer
Kenneth H. Kraemer National Institutes of Health
Michael M. Seidman
Michael M. Seidman National Institutes of Health
William A. Haseltine
William A. Haseltine Human Genome Sciences (United States)
Curtis C. Harris
Curtis C. Harris National Institutes of Health
Jeffrey A. Simon
Jeffrey A. Simon University of Minnesota
Kazumasa Wakamatsu
Kazumasa Wakamatsu Fujita Health University
Etelvino J. H. Bechara
Etelvino J. H. Bechara Universidade de São Paulo
Roger R. Reddel
Roger R. Reddel Children's Medical Research Institute
Ruth Halaban
Ruth Halaban Yale University
Marcus Bosenberg
Marcus Bosenberg Yale University

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