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Molecular Biology
USA
2026

D-Index & Metrics

Molecular Biology

D-Index
145
Citations
65022
World Ranking
100
National Ranking
64

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in United States Leader Award
  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 2023 - Research.com Molecular Biology in United States Leader Award
  • 2016 - Member of the National Academy of Medicine (NAM)
  • 2015 - Nobel Prize for mechanistic studies of DNA repair
  • 2005 - Member of the National Academy of Sciences
  • 2004 - Fellow of the American Academy of Arts and Sciences
  • 1994 - Fellow, The World Academy of Sciences

Overview

Aziz Sancar is affiliated with the University of North Carolina at Chapel Hill in the United States. The primary field of study is Biochemistry, Genetics, and Molecular Biology, with a total of 186 publications. Their work spans several subfields including Molecular Biology, Plant Science, Endocrine and Autonomic Systems, Cellular and Molecular Neuroscience, and Genetics.

The scientist's research focuses on several main topics, such as:

  • DNA Repair Mechanisms
  • Light effects on plants
  • CRISPR and Genetic Engineering
  • Circadian rhythm and melatonin
  • Photoreceptor and optogenetics research
  • DNA and Nucleic Acid Chemistry
  • Advanced biosensing and bioanalysis techniques

Among recent papers authored or co-authored by Aziz Sancar are:

  • Clocks, cancer, and chronochemotherapy, 2020, Science
  • Molecular mechanism of the repressive phase of the mammalian circadian clock, 2020, Proceedings of the National Academy of Sciences
  • The circadian clock shapes the Arabidopsis transcriptome by regulating alternative splicing and alternative polyadenylation, 2020, Journal of Biological Chemistry
  • Circadian clock, carcinogenesis, chronochemotherapy connections, 2021, Journal of Biological Chemistry
  • Molecular Mechanisms of Transcription-Coupled Repair, 2023, Annual Review of Biochemistry

Frequent collaborators in their research include:

  • Christopher P. Selby
  • Laura A. Lindsey-Boltz
  • Joyce T. Reardon
  • Michael G. Kemp
  • Jinchuan Hu

Aziz Sancar's publications have appeared in multiple venues, with the most common being:

  • UNC Libraries
  • Journal of Biological Chemistry
  • Proceedings of the National Academy of Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research

The scientist has also contributed to book publications, including a title published by the Royal Society of Chemistry:

  • DNA Damage, DNA Repair and Disease, 2020

Aziz Sancar has received multiple awards, including:

  • Member of the National Academy of Medicine (NAM), 2016
  • Nobel Prize, 2015, for mechanistic studies of DNA repair
  • Member of the National Academy of Sciences, 2005
  • Fellow of the American Academy of Arts and Sciences, 2004
  • Fellow, The World Academy of Sciences, 1994

Best Publications

  • Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints

    Aziz Sancar;Laura A Lindsey-Boltz;Keziban Unsal-Kaçmaz;Stuart Linn

  • Structure and function of DNA photolyase and cryptochrome blue-light photoreceptors.

    Aziz Sancar

  • DNA excision repair

    Aziz Sancar

  • DNA REPAIR ENZYMES

    Aziz Sancar;Gwendolyn B. Sancar

  • Simple method for identification of plasmid-coded proteins.

    A Sancar;A M Hack;W D Rupp

  • Structure and Function of DNA Photolyase

    Aziz Sancar

  • Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2.

    Martha Hotz Vitaterna;Christopher P. Selby;Takeshi Todo;Hitoshi Niwa

  • Molecular mechanism of transcription-repair coupling

    Christopher P. Selby;Aziz Sancar

  • Mechanisms of DNA excision repair.

    Aziz Sancar

  • A novel repair enzyme: UVRABC excision nuclease of Escherichia coli cuts a DNA strand on both sides of the damaged region

    Aziz Sancar;W.Dean Rupp

  • Crystal structure of DNA photolyase from Escherichia coli.

    Hee Won Park;Sang Tae Kim;Sang Tae Kim;Aziz Sancar;Johann Deisenhofer

  • Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II

    Ronny Drapkin;Joyce T. Reardon;Athar Ansari;Juch Chin Huang

  • HUMAN MUTSALPHA RECOGNIZES DAMAGED DNA BASE PAIRS CONTAINING O6-METHYLGUANINE, O4-METHYLTHYMINE, OR THE CISPLATIN-D(GPG) ADDUCT

    Derek R. Duckett;James T. Drummond;Alastair I. H. Murchie;Joyce T. Reardon

  • Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer.

    Juch-Chin Huang;Daniel L. Svoboda;Joyce T. Reardon;Aziz Sancar

  • Reconstitution of Human DNA Repair Excision Nuclease in a Highly Defined System

    David Mu;Chi-Hyun Park;Tsukasa Matsunaga;David S. Hsu

  • Vitamin B2-based blue-light photoreceptors in the retinohypothalamic tract as the photoactive pigments for setting the circadian clock in mammals

    Yasuhide Miyamoto;Aziz Sancar

  • Reaction Mechanism of Human DNA Repair Excision Nuclease

    David Mu;David S. Hsu;Aziz Sancar

  • Role of Mouse Cryptochrome Blue-Light Photoreceptor in Circadian Photoresponses

    Randy J. Thresher;Martha Hotz Vitaterna;Yasuhide Miyamoto;Aleksey Kazantsev

  • HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease.

    Juch Chin Huang;Deborah B. Zamble;Joyce T. Reardon;Stephen J. Lippard

  • In vitro Repair of Oxidative DNA Damage by Human Nucleotide Excision Repair System: Possible Explanation for Neurodegeneration in Xeroderma Pigmentosum Patients

    Joyce T. Reardon;Tadayoshi Bessho;Hsiang Chuan Kung;Philip H. Bolton

Frequent Co-Authors

Joyce T. Reardon
Joyce T. Reardon University of North Carolina at Chapel Hill
Dongping Zhong
Dongping Zhong The Ohio State University
John E. Hearst
John E. Hearst University of California, Berkeley
John B. Hogenesch
John B. Hogenesch Cincinnati Children's Hospital Medical Center
Jack D. Griffith
Jack D. Griffith University of North Carolina at Chapel Hill
Paul Modrich
Paul Modrich Duke University
William K. Kaufmann
William K. Kaufmann AsystBio (United States)
John-Stephen Taylor
John-Stephen Taylor Washington University in St. Louis
Jerard Hurwitz
Jerard Hurwitz Memorial Sloan Kettering Cancer Center
Yun Li
Yun Li University of North Carolina at Chapel Hill

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