World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
86
Citations
22611
World Ranking
832
National Ranking
439

Research.com Recognitions

  • 2005 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1968 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

John E. Hearst is affiliated with the University of California, Berkeley in the United States. Their research is primarily situated within the fields of Biochemistry, Genetics, and Molecular Biology. Within these broad areas, the scientist has contributed specifically to Molecular Biology and Biochemistry.

Their work covers several main topics including:

  • Phytochemicals and Antioxidant Activities
  • Phytochemical compounds biological activities
  • Natural product bioactivities and synthesis
  • DNA and Nucleic Acid Chemistry

Hearst's recent publications are all from the year 2020 and published in the venue UNC Libraries. These papers include:

  • "RecA-dependent incision of psoralen-crosslinked DNA by (A)BC excinuclease"
  • "Removal of psoralen monoadducts and crosslinks by human cell free extracts"
  • "Evidence for structural deformation of the DNA helix by a psoralen diadduct but not by a monoadduct"

Frequent collaborators in their research include Aziz Sancar, Suzanne Cheng, Joyce T. Reardon, Peter Spielmann, and Juch chin Huang. Aziz Sancar appears as a coauthor on two publications, while the others have contributed to one paper each.

The scientist has been recognized with awards such as the Fellow of the American Association for the Advancement of Science (AAAS) in 2005 and the Fellowship of the John Simon Guggenheim Memorial Foundation in 1968.

Best Publications

  • Psoralens as photoactive probes of nucleic acid structure and function: organic chemistry, photochemistry, and biochemistry

    George D. Cimino;Howard B. Gamper;Stephen T. Isaacs;John E . Hearst

  • Genes acrA and acrB encode a stress‐induced efflux system of Escherichia coli

    Dzwokai Ma;David N. Cook;Marie Alberti;Ning G. Pon

  • Molecular cloning and characterization of acrA and acrE genes of Escherichia coli.

    D Ma;D N Cook;M Alberti;N G Pon

  • The local repressor AcrR plays a modulating role in the regulation of acrAB genes of Escherichia coli by global stress signals

    Dzwokai Ma;Marie Alberti;Christy Lynch;Hiroshi Nikaido

  • Nucleotide and deduced polypeptide sequences of the photosynthetic reaction-center, B870 antenna, and flanking polypeptides from R. capsulata.

    Douglas C. Youvan;Edward J. Bylina;Edward J. Bylina;Marie Alberti;Helmut Begusch

  • Sedimentation Constants of Broken Chains and Wormlike Coils

    John E. Hearst;Walter H. Stockmayer

  • Carotenoids 2: Genetics and molecular biology of carotenoid pigment biosynthesis.

    Gregory A. Armstrong;John E. Hearst

  • Nucleotide sequence, organization, and nature of the protein products of the carotenoid biosynthesis gene cluster of Rhodobacter capsulatus

    Gregory A. Armstrong;Marie Alberti;Francesca Leach;John E. Hearst;John E. Hearst

  • Synthesis and characterization of new psoralen derivatives with superior photoreactivity with DNA and RNA

    Stephen T. Isaacs;Che-Kun James Shen;John E. Hearst;Henry Rapoport

  • Photochemical inactivation of viruses and bacteria in platelet concentrates by use of a novel psoralen and long-wavelength ultraviolet light

    L Lin;D N Cook;G P Wiesehahn;R Alfonso

  • A random-walk/giant-loop model for interphase chromosomes.

    R K Sachs;G van den Engh;B Trask;H Yokota

  • Evidence for the organization of chromatin in megabase pair-sized loops arranged along a random walk path in the human G0/G1 interphase nucleus.

    H Yokota;G van den Engh;J E Hearst;R K Sachs

  • A topological model for transcription based on unwinding angle analysis of E. coli RNA polymerase binary, initiation and ternary complexes

    Howard B. Gamper;John E. Hearst

  • On Polymer Dynamics

    R. A. Harris;J. E. Hearst

  • Luminescence resonance energy transfer

    Paul R. Selvin;Tariq M. Rana;John E. Hearst

  • Psoralen-deoxyribonucleic acid photoreaction. Characterization of the monoaddition products from 8-methoxypsoralen and 4,5'8-trimethylpsoralen.

    David Kanne;Kenneth Straub;Henry Rapoport;John E. Hearst

  • Genetic-physical mapping of a photosynthetic gene cluster from R. capsulata

    Krisztina M. Zsebo;John E. Hearst;John E. Hearst

  • Inhibiting proliferation of arterial smooth muscle cells

    John E. Hearst;William M. Greenman;Susan Wollowitz;Ryan D. Alfonso

  • Isolation and characterization of pyrimidine-psoralen-pyrimidine photodiadducts from DNA

    David Kanne;Kenneth Straub;John E. Hearst;Henry Rapoport

  • Post-PCR sterilization: a method to control carryover contamination for the polymerase chain reaction.

    George D. Cimino;Kenneth C. Metchette;John W. Tessman;John E. Hearst

Frequent Co-Authors

Aziz Sancar
Aziz Sancar University of North Carolina at Chapel Hill
Carl W. Schmid
Carl W. Schmid University of California, Davis
Melvin P. Klein
Melvin P. Klein Lawrence Berkeley National Laboratory
John F. Thompson
John F. Thompson Helicos Biosciences (United States)
Jerome Vinograd
Jerome Vinograd California Institute of Technology
Thomas R. Cech
Thomas R. Cech University of Colorado Boulder
Henry Rapoport
Henry Rapoport University of California, Berkeley
Michael R. Botchan
Michael R. Botchan University of California, Berkeley
Kenneth Sauer
Kenneth Sauer Lawrence Berkeley National Laboratory
Hiroshi Nikaido
Hiroshi Nikaido University of California, Berkeley

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