The scientist’s investigation covers issues in Efflux, Escherichia coli, Microbiology, Multiple drug resistance and Drug resistance. His Efflux study deals with the bigger picture of Biochemistry. His Escherichia coli research focuses on Membrane transport protein and how it relates to Integral membrane protein and Bacterial outer membrane.
His Microbiology research includes themes of Enterobacteriaceae and Salmonella. His studies in Multiple drug resistance integrate themes in fields like Response regulator, Signal transduction, Binding site and Transcription factor. His study in Drug resistance is interdisciplinary in nature, drawing from both Plasmid and Novobiocin.
His primary areas of investigation include Efflux, Microbiology, Escherichia coli, Multiple drug resistance and Drug resistance. His Efflux study incorporates themes from Plasmid, Novobiocin, Mutant and Bacterial outer membrane. His Microbiology research is multidisciplinary, incorporating perspectives in Salmonella enterica, Salmonella, Bacteria and Virulence.
His work carried out in the field of Escherichia coli brings together such families of science as Molecular biology, Membrane transport protein and Response regulator. His work deals with themes such as Regulator, Operon and Pseudomonas aeruginosa, which intersect with Multiple drug resistance. His Drug resistance research includes elements of Xenobiotic, Drug and Bacterial genome size.
His primary scientific interests are in Efflux, Microbiology, Multiple drug resistance, Pseudomonas aeruginosa and Biophysics. His biological study spans a wide range of topics, including Bacterial outer membrane and Mutant, Transporter, Gene. The study incorporates disciplines such as Drug and Virulence in addition to Microbiology.
His work in Virulence addresses subjects such as Plasmid, which are connected to disciplines such as Salmonella. His Multiple drug resistance research is multidisciplinary, relying on both Regulator, Biotechnology and Pharmaceutical microbiology. Kunihiko Nishino works mostly in the field of Binding site, limiting it down to topics relating to Multidrug transporter and, in certain cases, Escherichia coli, as a part of the same area of interest.
Efflux, Mutant, Biophysics, Pseudomonas aeruginosa and Binding site are his primary areas of study. Kunihiko Nishino has researched Efflux in several fields, including Multidrug Resistance-Associated Proteins, Plasma protein binding and Membrane transport protein. His Mutant research is multidisciplinary, relying on both Multiple drug resistance, Steric effects, Stereochemistry and Transmembrane domain.
His Biophysics research is multidisciplinary, incorporating elements of Amino acid, Random coil, Transport protein and Allosteric regulation. Kunihiko Nishino combines subjects such as Amikacin, Antibiotic resistance and Microbiology with his study of Pseudomonas aeruginosa. His Binding site study combines topics in areas such as Transporter, Escherichia coli, Multidrug transporter, Pulmonary surfactant and Substrate.
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Analysis of a Complete Library of Putative Drug Transporter Genes in Escherichia coli
Kunihiko Nishino;Akihito Yamaguchi.
Journal of Bacteriology (2001)
Novel macrolide-specific ABC-type efflux transporter in Escherichia coli.
Nobuyoshi Kobayashi;Kunihiko Nishino;Akihito Yamaguchi.
Journal of Bacteriology (2001)
Virulence and drug resistance roles of multidrug efflux systems of Salmonella enterica serovar Typhimurium
Kunihiko Nishino;Tammy Latifi;Eduardo A. Groisman.
Molecular Microbiology (2006)
Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket
Ryosuke Nakashima;Keisuke Sakurai;Seiji Yamasaki;Kunihiko Nishino.
Nature (2011)
The Putative Response Regulator BaeR Stimulates Multidrug Resistance of Escherichia coli via a Novel Multidrug Exporter System, MdtABC
Satoshi Nagakubo;Kunihiko Nishino;Takahiro Hirata;Akihito Yamaguchi.
Journal of Bacteriology (2002)
Dissecting the PhoP regulatory network of Escherichia coli and Salmonella enterica
Igor Zwir;Dongwoo Shin;Akinori Kato;Kunihiko Nishino.
Proceedings of the National Academy of Sciences of the United States of America (2005)
AcrAB Multidrug Efflux Pump Regulation in Salmonella enterica serovar Typhimurium by RamA in Response to Environmental Signals
Eiji Nikaido;Akihito Yamaguchi;Kunihiko Nishino;Kunihiko Nishino.
Journal of Biological Chemistry (2008)
Structural basis for the inhibition of bacterial multidrug exporters
Ryosuke Nakashima;Keisuke Sakurai;Seiji Yamasaki;Katsuhiko Hayashi.
Nature (2013)
Mechanisms of antibiotic resistance
Jun Lin;Kunihiko Nishino;Marilyn C. Roberts;Marcelo Tolmasky.
Frontiers in Microbiology (2015)
EvgA of the Two-Component Signal Transduction System Modulates Production of the YhiUV Multidrug Transporter in Escherichia coli
Kunihiko Nishino;Akihito Yamaguchi.
Journal of Bacteriology (2002)
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