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Microbiology

D-Index
98
Citations
43219
World Ranking
450
National Ranking
49

Overview

Laura J. V. Piddock is affiliated with the University of Birmingham in the United Kingdom. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with significant contributions to subfields including Molecular Medicine, Pharmacology, Applied Microbiology and Biotechnology, Public Health, Environmental and Occupational Health, and Pollution.

The scientist's scholarly output addresses several core topics related to antibiotics and bacterial resistance. These topics include:

  • Antibiotic Resistance in Bacteria
  • Antibiotic Use and Resistance
  • Antibiotics Pharmacokinetics and Efficacy
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Neonatal and Maternal Infections
  • Bacterial Genetics and Biotechnology
  • Salmonella and Campylobacter epidemiology

Laura J. V. Piddock has authored or co-authored several recent papers covering aspects of antimicrobial research. Notable publications include:

  • Towards the sustainable discovery and development of new antibiotics, 2021, Nature Reviews Chemistry
  • Systematic review and meta-analysis of in vitro efficacy of antibiotic combination therapy against carbapenem-resistant Gram-negative bacilli, 2021, International Journal of Antimicrobial Agents
  • Chlorpromazine and Amitriptyline Are Substrates and Inhibitors of the AcrB Multidrug Efflux Pump, 2020, mBio
  • Unrealized targets in the discovery of antibiotics for Gram-negative bacterial infections, 2023, Nature Reviews Drug Discovery
  • Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB, 2020, Nature Communications

The frequent co-authors with whom Laura J. V. Piddock has collaborated include:

  • Vito Ricci
  • Sally Ellis
  • F. Franceschi
  • Mike Sharland
  • Jack Stone

Thevenues in which they have most frequently published reflect a concentration in the antimicrobial and microbiological sciences. These publication venues are:

  • Journal of Antimicrobial Chemotherapy
  • mBio
  • ACS Infectious Diseases
  • Antimicrobial Agents and Chemotherapy
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Molecular mechanisms of antibiotic resistance.

    Jessica M A Blair;Mark A Webber;Alison J Baylay;David O Ogbolu

  • Understanding the mechanisms and drivers of antimicrobial resistance

    Alison H Holmes;Luke S P Moore;Arnfinn Sundsfjord;Arnfinn Sundsfjord;Martin Steinbakk

  • The Comprehensive Antibiotic Resistance Database

    Andrew G. McArthur;Nicholas Waglechner;Fazmin Nizam;Austin Yan

  • Multidrug-resistance efflux pumps ? not just for resistance

    Laura J. V. Piddock

  • Diagnosis, treatment and prophylaxis of spontaneous bacterial peritonitis: a consensus document

    Antoni Rimola;Guadalupe García-Tsao;Miquel Navasa;Laura J.V. Piddock

  • Clinically Relevant Chromosomally Encoded Multidrug Resistance Efflux Pumps in Bacteria

    Laura J. V. Piddock

  • Tackling antibiotic resistance

    Karen Bush;Patrice Courvalin;Gautam Dantas;Julian Davies

  • The importance of efflux pumps in bacterial antibiotic resistance

    M. A. Webber;L. J. V. Piddock

  • Fluoroquinolone resistance: mechanisms, impact on bacteria, and role in evolutionary success

    Liam S. Redgrave;Sam B. Sutton;Mark A. Webber;Laura J.V. Piddock

  • Towards the sustainable discovery and development of new antibiotics

    Marcus Miethke;Marco Pieroni;Tilmann Weber;Mark Brönstrup

  • Multidrug efflux pumps: structure, function and regulation

    Dijun Du;Xuan Wang-Kan;Arthur Neuberger;Hendrik W. van Veen

  • Bacterial efflux pump inhibitors from natural sources

    Michael Stavri;Laura J. V. Piddock;Simon Gibbons

  • The crisis of no new antibiotics--what is the way forward?

    Laura J V Piddock

  • Antibiotic resistance genes, integrons and multiple antibiotic resistance in thirty-five serotypes of Salmonella enterica isolated from humans and animals in the UK

    L. P. Randall;S. W. Cooles;M. K. Osborn;L. J. V. Piddock

  • Contributions of individual mechanisms to fluoroquinolone resistance in 36 Escherichia coli strains isolated from humans and animals.

    M. J. Everett;Yu Fang Jin;V. Ricci;L. J. V. Piddock

  • Multidrug efflux pumps in Gram-negative bacteria and their role in antibiotic resistance

    Jessica M A Blair;Grace E Richmond;Laura J V Piddock

  • Mechanisms of fluoroquinolone resistance: an update 1994-1998.

    Laura J. V. Piddock

  • Quinolone-resistant Salmonella typhi in Viet Nam: molecular basis of resistance and clinical response to treatment

    John Wain;Nguyen T. T. Hoa;Nguyen T. Chinh;Ha Vinh

  • Discovery research: the scientific challenge of finding new antibiotics

    David M. Livermore;Martin Blaser;Otto Carrs;Gail Cassell

  • Structure, function and inhibition of RND efflux pumps in Gram-negative bacteria: an update.

    Jessica M A Blair;Laura J V Piddock

  • Antimicrobials: access and sustainable eff ectiveness 2 Understanding the mechanisms and drivers of antimicrobial resistance

    Alison H Holmes;Luke S P Moore;Martin Steinbakk;Sadie Regmi

Frequent Co-Authors

Mark A. Webber
Mark A. Webber University of East Anglia
Martin J. Woodward
Martin J. Woodward University of Reading
Alasdair Ivens
Alasdair Ivens University of Edinburgh
Tom J. Humphrey
Tom J. Humphrey Swansea University
John Wain
John Wain University of East Anglia
Steven J. Projan
Steven J. Projan Rutgers, The State University of New Jersey
Roberto M. La Ragione
Roberto M. La Ragione University of Surrey
Peter M. Hawkey
Peter M. Hawkey University of Birmingham
David M. Livermore
David M. Livermore University of East Anglia
Ian Chopra
Ian Chopra University of Leeds

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